Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Csaba Mahotka"'
Single-cell transcriptome profiling of human HSCs during development: new insights into HSC ontogeny
Autor:
Edgar Grinstein, Csaba Mahotka
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/c7a856a58ce64f8988a98614df3c49d5
Autor:
Csaba Toth, Sarah Funke, Vanessa Nitsche, Anna Liverts, Viktoriya Zlachevska, Marcia Gasis, Constanze Wiek, Helmut Hanenberg, Csaba Mahotka, Peter Schirmacher, Sebastian Heikaus
Publikováno v:
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-14 (2017)
Abstract Background Renal cell carcinomas (RCCs) display broad resistance against conventional radio- and chemotherapies, which is due at least in part to impairments in both extrinsic and intrinsic apoptotic pathways. One important anti-apoptotic fa
Externí odkaz:
https://doaj.org/article/719614e47c2b4761a2747fcd0330dbeb
PIDDosome Expression and the Role of Caspase-2 Activation for Chemotherapy-Induced Apoptosis in RCCs
Publikováno v:
Cellular Oncology, Vol 32, Iss 1-2, Pp 29-42 (2010)
Background: The importance of caspase-2 activation for mediating apoptosis in cancer is not clear and seems to differ between different tumour types. Furthermore, only few data have been obtained concerning the expression of caspase-2, which can be a
Externí odkaz:
https://doaj.org/article/0e5c1332b20f4a9ea865973ab3126219
Autor:
Sebastian Heikaus, Linda van den Berg, Tobias Kempf, Csaba Mahotka, Helmut Erich Gabbert, Uwe Ramp
Publikováno v:
Cellular Oncology, Vol 30, Iss 5, Pp 419-433 (2008)
Renal cell carcinomas (RCCs) exhibit a marked resistance towards apoptosis. Although most apoptotic stimuli converge at the level of the mitochondria, little is known about the mitochondrial apoptosis pathway in renal cell carcinomas. The aim of the
Externí odkaz:
https://doaj.org/article/4a8d5d0e03bc458fa719a3165b21c867
Autor:
Anja Troeger, Meinolf Siepermann, Gabriele Escherich, Roland Meisel, Reinhardt Willers, Sonja Gudowius, Thomas Moritz, Hans-Juergen Laws, Helmut Hanenberg, Ulrich Goebel, Gritta E. Janka-Schaub, Csaba Mahotka, Dagmar Dilloo
Publikováno v:
Haematologica, Vol 92, Iss 8 (2007)
Background and Objectives Impaired apoptosis, mediated by members of the inhibitor of apoptosis proteins (IAP) family such as survivin, is thought to contribute to leukemic cell survival. In contrast to low expression of survivin in normal differenti
Externí odkaz:
https://doaj.org/article/3d0ee74ddebe4dd49a5623fcf7352b5f
Publikováno v:
Leukemia
Leukemia, 35(12):36163618
Leukemia, 35(12):36163618
Publikováno v:
Leukemia. 32:1865-1868
Publikováno v:
Leukemia. 33(4)
Publikováno v:
Cellular Signalling. 23:1358-1365
Retinoblastoma protein (Rb) controls cell proliferation, differentiation, survival and gene expression and it has a central role in the signaling network that provides a cell cycle checkpoint in the G1 phase of the cell cycle. Studies in mice have sh
Autor:
Sarah Funke, Helmut Hanenberg, Rainer Engers, Edgar Grinstein, Csaba Mahotka, Helmut E. Gabbert, Sebastian Heikaus, Christoph V. Suschek, Uwe Ramp, Wiebke Wetzel, Nils Wethkamp
Publikováno v:
Journal of Biological Chemistry. 286:19576-19588
Daxx is involved in transcriptional control and apoptosis. It comprises several domains, including a regulatory C terminus that is responsible for the interaction with numerous proteins such as p53, promyelocytic leukemia protein (PML), and Hsp27. He