Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Csaba Leranth"'
Autor:
Mari S. Golub, Edward P. Hackett, Casey E. Hogrefe, Csaba Leranth, John D. Elsworth, Robert H. Roth
Publikováno v:
Developmental Cognitive Neuroscience, Vol 26, Iss , Pp 52-61 (2017)
Potential long term effects on brain development are a concern when drugs are used to treat depression and anxiety in childhood. In this study, male juvenile rhesus monkeys (three-four years of age) were dosed with fluoxetine or vehicle (N = 16/group
Externí odkaz:
https://doaj.org/article/df482301885546ee80a743bcbaffa943
Autor:
Dustin R. Wakeman, Stephanie Weiss, John R. Sladek, John D. Elsworth, Brian Bauereis, Csaba Leranth, Patrick J. Hurley, Robert H. Roth, D. Eugene Redmond
Publikováno v:
Cell Transplantation, Vol 23 (2014)
A human embryonic stem cell (HESC) line, H1, was studied after differentiation to a dopaminergic phenotype in vitro in order to carry out in vivo studies in Parkinsonian monkeys. To identify morphological characteristics of transplanted donor cells,
Externí odkaz:
https://doaj.org/article/10d97af286b349a0bb06663cdac536d0
Autor:
Tibor Hajszan, Orsolya Huzian, Csaba Leranth, Tamás Farkas, Eszter Csakvari, Nikoletta Dobos, Judith Baka, Ronald S. Duman, László Siklós
Publikováno v:
Neuroscience. 459:85-103
The synaptogenic hypothesis of major depressive disorder implies that preventing the onset of depressive-like behavior also prevents the loss of hippocampal spine synapses. By applying the psychoactive drugs, diazepam and fluoxetine, we investigated
Publikováno v:
Vitamins and hormones. 114
The concept that estradiol may act as a local neuromodulator in the brain, rapidly affecting connectivity and synaptic function, has been firmly established by research over the last 30 years. De novo synthesis of estradiol within the brain as well a
The concept that estradiol may act as a local neuromodulator in the brain, rapidly affecting connectivity and synaptic function, has been firmly established by research over the last 30 years. De novo synthesis of estradiol within the brain as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaac0da0e482a8f7adc41a4360adce53
https://doi.org/10.1016/bs.vh.2020.06.002
https://doi.org/10.1016/bs.vh.2020.06.002
Autor:
Robert H. Roth, James David Jentsch, Stephanie M. Groman, John D. Elsworth, Eugene Redmond, Csaba Leranth
Publikováno v:
Journal of Comparative Neurology. 523:1248-1257
Bisphenol-A (BPA) is widely used in the manufacture of plastics, epoxy resins, and certain paper products. A majority of the population in the developed world is routinely exposed to BPA from multiple sources and has significant circulating levels of
Autor:
Casey E. Hogrefe, Robert H. Roth, John D. Elsworth, Csaba Leranth, Edward Hackett, Mari S. Golub
Publikováno v:
Developmental Cognitive Neuroscience, Vol 26, Iss, Pp 52-61 (2017)
Potential long term effects on brain development are a concern when drugs are used to treat depression and anxiety in childhood. In this study, male juvenile rhesus monkeys (three-four years of age) were dosed with fluoxetine or vehicle (N = 16/group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f487448a070e5bca9a3c1978a86fb6
https://escholarship.org/uc/item/70m7k99j
https://escholarship.org/uc/item/70m7k99j
Autor:
Dustin R. Wakeman, R. Jude Samulski, Csaba Leranth, Hemraj B. Dodiya, John R. Sladek, D. Eugene Redmond, Yang D. Teng, Evan Y. Snyder
Publikováno v:
Stem Cells Translational Medicine. 3:692-701
Transplanted multipotent human fetal neural stem cells (hfNSCs) significantly improved the function of parkinsonian monkeys in a prior study primarily by neuroprotection, with only 3%–5% of cells expressing a dopamine (DA) phenotype. In this paper,
Autor:
Caleb R.S. McEntire, Kimberly B. Bjugstad, John D. Elsworth, Robert H. Roth, D. Eugene Redmond, Csaba Leranth, Richard Jude Samulski, John R. Sladek, Joseph P Kingsbery
Publikováno v:
Molecular Therapy. 21(12):2160-2168
We combined viral vector delivery of human glial-derived neurotrophic factor (GDNF) with the grafting of dopamine (DA) precursor cells from fetal ventral mesencephalon (VM) to determine whether these strategies would improve the anti-Parkinson's effe
Publikováno v:
International Journal of Neuropsychopharmacology. 16:905-912
Parkinson's disease is usually characterized as a movement disorder; however cognitive abilities that are dependent on the prefrontal cortex decline at an early stage of the disease in most patients. The changes that underlie cognitive deficits in Pa