Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Csaba Harasztosi"'
Autor:
Daria Savitska, Morgan Hess, Dila Calis, Philine Marchetta, Csaba Harasztosi, Stefan Fink, Philipp Eckert, Peter Ruth, Lukas Rüttiger, Marlies Knipper, Wibke Singer
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
In light of the increasing evidence supporting a link between hearing loss and dementia, it is critical to gain a better understanding of the nature of this relationship. We have previously observed that following cochlear synaptopathy, the temporal
Externí odkaz:
https://doaj.org/article/f65ea4893a514acd80a52bfb962e41dd
Autor:
Sandra Beer-Hammer, Sze Chim Lee, Stephanie A. Mauriac, Veronika Leiss, Isabel A. M. Groh, Ana Novakovic, Roland P. Piekorz, Kirsten Bucher, Chengfang Chen, Kun Ni, Wibke Singer, Csaba Harasztosi, Thomas Schimmang, Ulrike Zimmermann, Klaus Pfeffer, Lutz Birnbaumer, Andrew Forge, Mireille Montcouquiol, Marlies Knipper, Bernd Nürnberg, Lukas Rüttiger
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 4, Pp 1509-1532 (2018)
Background/Aims: From invertebrates to mammals, Gαi proteins act together with their common binding partner Gpsm2 to govern cell polarization and planar organization in virtually any polarized cell. Recently, we demonstrated that Gαi3-deficiency in
Externí odkaz:
https://doaj.org/article/203fa545a978464bb8f4c71da5a88657
Autor:
Lucas Matt, Philipp Eckert, Rama Panford-Walsh, Hyun-Soon Geisler, Anne E. Bausch, Marie Manthey, Nicolas I. C. Müller, Csaba Harasztosi, Karin Rohbock, Peter Ruth, Eckhard Friauf, Thomas Ott, Ulrike Zimmermann, Lukas Rüttiger, Thomas Schimmang, Marlies Knipper, Wibke Singer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Activity-dependent BDNF (brain-derived neurotrophic factor) expression is hypothesized to be a cue for the context-specificity of memory formation. So far, activity-dependent BDNF cannot be explicitly monitored independently of basal BDNF levels. We
Externí odkaz:
https://doaj.org/article/2faea4599765498aaa60723cb0df0f72
Publikováno v:
European Journal of Neuroscience. 54:4755-4767
The plasma-membrane marker FM1-43 was employed to reveal the relative significance of different types of endocytic and transcytic mechanisms in outer hair cells (OHCs) of the guinea-pig cochlea. A double-barrel local perfusion system was used to labe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9be2ec1af64c7d17c968db2954db31
https://doi.org/10.1111/ejn.15331
https://doi.org/10.1111/ejn.15331
Autor:
Lukas Rüttiger, Stuart L. Johnson, Adam J Carlton, Kevin P. Legan, Jing-Yi Jeng, Philine Marchetta, Guy P. Richardson, Richard J. Goodyear, Laura F. Corns, Csaba Harasztosi, Walter Marcotti
Publikováno v:
The Journal of Physiology. 599:2015-2036
Key points The aim was to determine whether detachment of the tectorial membrane (TM) from the organ of Corti in Tecta/Tectb-/- mice affects the biophysical properties of cochlear outer hair cells (OHCs). Tecta/Tectb-/- mice have highly elevated hear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d15f54f9c4900b80472ef820361d2d9
https://doi.org/10.1113/jp280905
https://doi.org/10.1113/jp280905
Autor:
Lukas Rüttiger, Thomas Schimmang, Steffen Wolter, María Beatriz Durán‐Alonso, Katja Gutsche, José López-Barneo, Csaba Harasztosi, Iris López-Hernández, Marlies Knipper, Alberto Pascual
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Glial‐derived neurotrophic factor (GDNF) has been proposed as a potent neurotrophic factor with the potential to cure neurodegenerative diseases. In the cochlea, GDNF has been detected in auditory neurons and sensory receptor cells and its expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f997a06e8273b693477b7af2db47cb4
https://doi.org/10.1002/jnr.24544
https://doi.org/10.1002/jnr.24544
Autor:
Jing-Yi, Jeng, Csaba, Harasztosi, Adam J, Carlton, Laura F, Corns, Philine, Marchetta, Stuart L, Johnson, Richard J, Goodyear, Kevin P, Legan, Lukas, Rüttiger, Guy P, Richardson, Walter, Marcotti
Publikováno v:
J Physiol
The tectorial membrane (TM) is an acellular structure of the cochlea that is attached to the stereociliary bundles of the outer hair cells (OHCs), electro-motile cells that amplify motion of the cochlear partition and sharpen its frequency selectivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b93afcadf27482a13b0bbb9a84bf7d7
https://pubmed.ncbi.nlm.nih.gov/33559882
https://pubmed.ncbi.nlm.nih.gov/33559882
Autor:
Philipp Eckert, Kohei Yamahara, Lukas Rüttiger, Miriam A. Vogt, Ulrike Zimmermann, Mirko Jaumann, Marie Manthey, Marlies Knipper, Wibke Singer, Philipp Armbruster, Michela Dotta, Csaba Harasztosi, Kamyar Kasini
Publikováno v:
The FASEB Journal. 32:3005-3019
Systemic corticosteroids have been the mainstay of treatment for various hearing disorders for more than 30 yr. Accordingly, numerous studies have described glucocorticoids (GCs) and stressors to be protective in the auditory organ against damage ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15df449c6e5a181e8765a34b0164e7f2
https://doi.org/10.1096/fj.201701041rrr
https://doi.org/10.1096/fj.201701041rrr
Publikováno v:
Journal of Neuroscience Methods. 293:310-320
Background Fluorescence membrane markers are efficient tools for visualizing the dynamics of membrane recycling processes in living cells. The outer hair cell (OHC) − a bipolar epithelial cell in the cochlea − possesses endocytic activity at both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24f6c9b8723d1e3ef6d7176c67fee32
https://doi.org/10.1016/j.jneumeth.2017.10.014
https://doi.org/10.1016/j.jneumeth.2017.10.014