Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Csaba, Miskey"'
Autor:
Chiara F. Magnani, Renier Myburgh, Silvan Brunn, Morgane Chambovey, Marianna Ponzo, Laura Volta, Francesco Manfredi, Christian Pellegrino, Steve Pascolo, Csaba Miskey, Zoltán Ivics, Judith A. Shizuru, Dario Neri, Markus G. Manz
Publikováno v:
Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 56-71 (2023)
Discrimination between hematopoietic stem cells and leukemic stem cells remains a major challenge for acute myeloid leukemia immunotherapy. CAR T cells specific for the CD117 antigen can deplete malignant and healthy hematopoietic stem cells before c
Externí odkaz:
https://doaj.org/article/fb577a1a841d43ec95f8517deb5c459e
Autor:
Ola Bagato, Anne Balkema-Buschmann, Daniel Todt, Saskia Weber, André Gömer, Bingqian Qu, Csaba Miskey, Zoltan Ivics, Thomas C. Mettenleiter, Stefan Finke, Richard J. P. Brown, Angele Breithaupt, Dmitry S. Ushakov
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Lung immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for the ability to deal with infection. Using light sheet fluorescence microscopy of hamster lung slices in combination with virological, immuno
Externí odkaz:
https://doaj.org/article/752b1d6443b247df8da3809cbeaac0e7
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14978 (2023)
Transposons are nature’s gene delivery vehicles that can be harnessed for experimental and therapeutic purposes. The Sleeping Beauty (SB) transposon shows efficient transposition and long-term transgene expression in human cells, and is currently u
Externí odkaz:
https://doaj.org/article/d5060f4c22fa4e278a271ed381025ae4
Autor:
Marcel G.E. Rommel, Lisa Walz, Foteini Fotopoulou, Saskia Kohlscheen, Franziska Schenk, Csaba Miskey, Lacramioara Botezatu, Yvonne Krebs, Iris M. Voelker, Kevin Wittwer, Tim Holland-Letz, Zoltán Ivics, Veronika von Messling, Marieke A.G. Essers, Michael D. Milsom, Christian K. Pfaller, Ute Modlich
Publikováno v:
Cell Reports, Vol 41, Iss 1, Pp 111447- (2022)
Summary: Respiratory tract infections are among the deadliest communicable diseases worldwide. Severe cases of viral lung infections are often associated with a cytokine storm and alternating platelet numbers. We report that hematopoietic stem and pr
Externí odkaz:
https://doaj.org/article/4f2b90b0b8ec49f9816a17097e7b27e9
Autor:
Márton Miskei, Adrienn Horváth, Lívia Viola, Laura Varga, Éva Nagy, Orsolya Feró, Zsolt Karányi, Jason Roszik, Csaba Miskey, Zoltán Ivics, Lóránt Székvölgyi
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4032-4041 (2021)
Throughout evolution, DNA transposons provide a recurrent supply of genetic information to give rise to novel gene functions by fusion of their transposase domain to various domains of host-encoded proteins. One of these “domesticated”, transposa
Externí odkaz:
https://doaj.org/article/4945dda44d4842a8996a212d7a8d6a0e
Autor:
Bo Gao, Wencheng Zong, Csaba Miskey, Numan Ullah, Mohamed Diaby, Cai Chen, Xiaoyan Wang, Zoltán Ivics, Chengyi Song
Publikováno v:
Mobile DNA, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background A family of Tc1/mariner transposons with a characteristic DD38E triad of catalytic amino acid residues, named Intruder (IT), was previously discovered in sturgeon genomes, but their evolutionary landscapes remain largely unknown.
Externí odkaz:
https://doaj.org/article/9ead1fbe935b4efc8d2eb344161e30c6
Autor:
Maria Hernandez, Sergio Recalde, Laura Garcia-Garcia, Jaione Bezunartea, Csaba Miskey, Sandra Johnen, Sabine Diarra, Attila Sebe, Juan Roberto Rodriguez-Madoz, Severine Pouillot, Corinne Marie, Zsuzsanna Izsvák, Daniel Scherman, Martina Kropp, Felipe Prosper, Gabriele Thumann, Zoltán Ivics, Alfredo Garcia-Layana, Patricia Fernandez-Robredo
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss , Pp 403-417 (2019)
Age-related macular degeneration (AMD) is a progressive retinal disorder characterized by imbalanced pro- and antiangiogenic signals. The aim of this study was to evaluate the effect of ex vivo cell-based gene therapy with stable expression of human
Externí odkaz:
https://doaj.org/article/5d42b7be628d4feab08c70665676e92a
Autor:
Larissa Mattern, Katrin Otten, Csaba Miskey, Matthias Fuest, Zsuzsanna Izsvák, Zoltán Ivics, Peter Walter, Gabriele Thumann, Sandra Johnen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12982 (2022)
More and more patients suffer from multifactorial neurodegenerative diseases, such as age-related macular degeneration (AMD). However, their pathological mechanisms are still poorly understood, which complicates the development of effective therapies
Externí odkaz:
https://doaj.org/article/7419709dbb994c579323e03439684f01
Autor:
Antonio Palazzo, Patrizio Lorusso, Csaba Miskey, Oliver Walisko, Andrea Gerbino, Carlo Marya Thomas Marobbio, Zoltán Ivics, René Massimiliano Marsano
Publikováno v:
Mobile DNA, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background We have recently described a peculiar feature of the promoters in two Drosophila Tc1-like elements, Bari1 and Bari3. The AT-richness and the presence of weak core-promoter motifs make these promoters, that we have defined “blurr
Externí odkaz:
https://doaj.org/article/3a61a2c33e9a4ecf8f5c6db46602d615
Autor:
Saisai Wang, Bo Gao, Csaba Miskey, Zhongxia Guan, Yatong Sang, Cai Chen, Xiaoyan Wang, Zoltán Ivics, Chengyi Song
Publikováno v:
Nucleic Acids Research. 51:1843-1858
The discovery of new, active DNA transposons can expand the range of genetic tools and provide more options for genomic manipulation. In this study, a bioinformatics analysis suggested that Passer (PS) transposons, which are members of the pogo super
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2afd27a56d5de2a7f49c2b3e94a34449
https://doi.org/10.1093/nar/gkad005
https://doi.org/10.1093/nar/gkad005