Preclinical evaluation of 'whole' cell vaccines for prophylaxis and therapy using a disabled infectious single cycle-herpes simplex virus vector to transduce cytokine genes

Autor: Sa, Ali, Cs, Mclean, Mike Boursnell, Martin G, Cl, Holmes, Reeder S, Entwisle C, Dm, Blakeley, Jg, Shields, Todryk S, Vile R, Ra, Robins, Rc, Rees

Publikováno v: Europe PubMed Central

The development of genetically modified "whole" tumor cell vaccines for cancer therapy relies on the efficient transduction and expression of genes by vectors. In the present study, we have used a disabled infectious single cycle-herpes simplex virus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6176b09d279e08ced01b6468bcce6212
https://pubmed.ncbi.nlm.nih.gov/10749137

Enhancing resiliency and optimizing readiness in military personnel through psychological flexibility training: design and methodology of a randomized controlled trial.

Autor: Peterson AL; Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.; Research and Development Service, South Texas Veterans Health Care System, San Antonio, TX, United States.; Department of Psychology, University of Texas at San Antonio, San Antonio, TX, United States., Moore BA; Department of Psychological Science, Kennesaw State University, Kennesaw, GA, United States., Evans WR; VA North Texas Health Care System, Dallas, TX, United States.; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, United States., Young-McCaughan S; Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.; Research and Development Service, South Texas Veterans Health Care System, San Antonio, TX, United States., Blankenship AE; Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States., Straud CL; Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.; Department of Psychology, University of Texas at San Antonio, San Antonio, TX, United States., McLean CS; 3rd Security Force Assistance Brigade, Fort Cavazos, TX, United States., Miller TL; 3rd Security Force Assistance Brigade, Fort Cavazos, TX, United States., Meyer EC; Department of Counseling and Behavioral Health, University of Pittsburgh, Pittsburgh, PA, United States.

Publikováno v: Frontiers in psychiatry [Front Psychiatry] 2024 Jan 05; Vol. 14, pp. 1299532. Date of Electronic Publication: 2024 Jan 05 (Print Publication: 2023).

Perceptual Decisions in the Presence of Relevant and Irrelevant Sensory Evidence.

Autor: Anders UM; Center for Neuroscience and Department of Neurobiology, Physiology and Behavior, University of California, Davis, Davis, CA, United States., McLean CS; Center for Neuroscience and Department of Neurobiology, Physiology and Behavior, University of California, Davis, Davis, CA, United States., Ouyang B; Center for Neuroscience and Department of Neurobiology, Physiology and Behavior, University of California, Davis, Davis, CA, United States., Ditterich J; Center for Neuroscience and Department of Neurobiology, Physiology and Behavior, University of California, Davis, Davis, CA, United States.

Publikováno v: Frontiers in neuroscience [Front Neurosci] 2017 Nov 10; Vol. 11, pp. 618. Date of Electronic Publication: 2017 Nov 10 (Print Publication: 2017).

Anti-tumour therapeutic efficacy of OX40L in murine tumour model.

Autor: Ali SA; School of Science, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK., Ahmad M, Lynam J, McLean CS, Entwisle C, Loudon P, Choolun E, McArdle SE, Li G, Mian S, Rees RC

Publikováno v: Vaccine [Vaccine] 2004 Sep 09; Vol. 22 (27-28), pp. 3585-94.

Tumor regression induced by intratumor therapy with a disabled infectious single cycle (DISC) herpes simplex virus (HSV) vector, DISC/HSV/murine granulocyte-macrophage colony-stimulating factor, correlates with antigen-specific adaptive immunity.

Autor: Ali SA; Department of Life Sciences, Nottingham Trent University, Nottingham, United Kingdom., Lynam J, McLean CS, Entwisle C, Loudon P, Rojas JM, McArdle SE, Li G, Mian S, Rees RC

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2002 Apr 01; Vol. 168 (7), pp. 3512-9.