Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Crystal Yuri Oh"'
Autor:
Haiqing Bai, Longlong Si, Amanda Jiang, Chaitra Belgur, Yunhao Zhai, Roberto Plebani, Crystal Yuri Oh, Melissa Rodas, Aditya Patil, Atiq Nurani, Sarah E. Gilpin, Rani K. Powers, Girija Goyal, Rachelle Prantil-Baun, Donald E. Ingber
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Mechanical forces in lungs facilitate breathing motions. Here the authors use a microfluidic human lung alveolus chip to study influenza infection and find that mechanical forces from active chips also induce innate inflammatory responses via, at lea
Externí odkaz:
https://doaj.org/article/a8197b35fe0e4313b281435e947641eb
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Human-to-human transmission of viruses, such as influenza viruses and coronaviruses, can promote virus evolution and the emergence of new strains with increased potential for creating pandemics. Clinical studies analyzing how a particular ty
Externí odkaz:
https://doaj.org/article/265603015c6f47feb745c6711a606107
Autor:
Longlong Si, Quan Shen, Jing Li, Li Chen, Jinying Shen, Xue Xiao, Haiqing Bai, Tang Feng, Adam Yongxin Ye, Le Li, Chunhe Zhang, Zhen Li, Ping Wang, Crystal Yuri Oh, Atiq Nurani, Siwen Niu, Chengxin Zhang, Xiaoqiong Wei, Wanqiong Yuan, Hao Liao, Xiaojie Huang, Ning Wang, Wen-xia Tian, Hongwei Tian, Li Li, Xiaoheng Liu, Roberto Plebani
Publikováno v:
Nature Biotechnology. 40:1370-1377
The usefulness of live attenuated virus vaccines has been limited by suboptimal immunogenicity, safety concerns or cumbersome manufacturing processes and techniques. Here we describe the generation of a live attenuated influenza A virus vaccine using
Autor:
Elee Shimshoni, Gwenn E. Merry, Zachary D. Milot, Crystal Yuri Oh, Viktor Horvath, Russell A. Gould, Joseph A. Caruso, Chira Chen-Tanyolac, Philippe Gascard, Veena Sangwan, Julie Bérubé, Swneke D. Bailey, Sean Hall, Matthew D. Stachler, Lorenzo Ferri, Thea D. Tlsty, Donald E. Ingber
Publikováno v:
Gastro Hep Advances.
Autor:
Xiao Tan, F Ann Ran, Nathaniel D. Tippens, James J. Collins, Emma J. Chory, Evan M. Zhao, Crystal Yuri Oh, Angelo S. Mao, Eric S Zigon, Tiffany Y Hua, Kehan Zhang, Pradeep Ramesh, David B. Thompson, Peter Q. Nguyen, Isaac Han, Max A English, Helena de Puig
Publikováno v:
Nature Biotechnology. 40:539-545
The ability to control translation of endogenous or exogenous RNAs in eukaryotic cells would facilitate a variety of biotechnological applications. Current strategies are limited by low fold changes in transgene output and the size of trigger RNAs (t
Autor:
Crystal Yuri Oh, Ilona Golynker, Sarah E. Gilpin, Haiqing Bai, Rachelle Prantil-Baun, Amanda Jiang, Danni Y. Zhu, Steven P. Gygi, Mercy Soong, Melissa Rodas, Marisa McGrath, Longlong Si, Robert Haupt, Seongmin Kim, James Logue, Daniel Blanco-Melo, Tristan X. Jordan, Randy A. Albrecht, Rasmus Møller, Tian Zhang, Donald E. Ingber, Kohei Oishi, Justin J. Frere, Kambez H. Benam, Daisy A. Hoagland, Girija Goyal, Kenneth E. Carlson, Wen-Chun Liu, Rani K. Powers, Shu Horiuchi, Benjamin E. Nilsson-Payant, Skyler Uhl, Roberto Plebani, Matthew B. Frieman, Benjamin R. tenOever, Stuart Weston, Atiq Nurani, Wuji Cao
Publikováno v:
Nature biomedical engineering
The rapid repurposing of antivirals is particularly pressing during pandemics. However, rapid assays for assessing candidate drugs typically involve in vitro screens and cell lines that do not recapitulate human physiology at the tissue and organ lev
Autor:
Longlong Si, Haiqing Bai, Crystal Yuri Oh, Amanda Jiang, Fan Hong, Tian Zhang, Yongxin Ye, Tristan X. Jordan, James Logue, Marisa McGrath, Chaitra Belgur, Karina Calderon, Atiq Nurani, Wuji Cao, Kenneth E. Carlson, Rachelle Prantil-Baun, Steven P. Gygi, Dong Yang, Colleen B. Jonsson, Benjamin R. tenOever, Matthew Frieman, Donald E. Ingber
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
The current coronavirus disease 2019 (COVID-19) pandemic highlights the need for broad-spectrum antiviral therapeutics. Here we describe a new class of self-assembling immunostimulatory short duplex RNAs that potently induce production of type I and
Autor:
Longlong Si, Haiqing Bai, Crystal Yuri Oh, Tian Zhang, Fan Hong, Amanda Jiang, Yongxin Ye, Tristan X. Jordan, James Logue, Marisa McGrath, Chaitra Belgur, Atiq Nurani, Wuji Cao, Rachelle Prantil-Baun, Steven P Gygi, Rani K. Powers, Matthew Frieman, Benjamin R. tenOever, Donald E. Ingber
Publikováno v:
bioRxiv : the preprint server for biology.
The current COVID-19 pandemic highlights the need for broad-spectrum antiviral therapeutics. Here we describe a new class of self-assembling immunostimulatory short duplex RNAs that potently induce production of type I and type III interferon (IFN-I
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
Microbiology Spectrum
Microbiology Spectrum
Human-to-human transmission of viruses, such as influenza viruses and coronaviruses, can promote virus evolution and the emergence of new strains with increased potential for creating pandemics. Clinical studies analyzing how a particular type of vir
Autor:
Longlong Si, Amanda Jiang, Atiq Nurani, Sarah E. Gilpin, Crystal Yuri Oh, Rani K. Powers, Chaitra Belgur, Rachelle Prantil-Baun, Girija Goyal, Donald E. Ingber, Haiqing Bai, Melissa Rodas
Publikováno v:
Nature communications. 13(1)
Mechanical forces associated with breathing play a fundamental role in lung development and disease but the molecular pathways remain largely unknown. Here, we used a mechanically actuatable Human Lung Alveolus Chip that recapitulates human lung alve