Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Crystal S.F. Cheung"'
Autor:
Michal Ad, Dimiter S. Dimitrov, Crystal S.F. Cheung, Max Colbert, Kevin M. Barnes, Jeffrey Baron, Audrey Lee, Julian C. Lui, Zhongyu Zhu
Publikováno v:
Molecular Therapy. 27:673-680
Recombinant human growth hormone (GH) is commonly used to treat short stature in children. However, GH treatment has limited efficacy, particularly in severe, non-GH-deficient conditions such as chondrodysplasias, and potential off-target effects. Be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e91c3b504b6b5ca315368d25171d39
https://doi.org/10.1016/j.ymthe.2019.01.017
https://doi.org/10.1016/j.ymthe.2019.01.017
Autor:
Crystal S.F. Cheung, Alon Herschhorn, Gwo-Yu Chuang, Arne Schön, Krisha McKee, Nicole A. Doria-Rose, Aliaksandr Druz, Yongping Yang, David R. Langley, Mark K. Louder, Tao Wang, Baoshan Zhang, Yen-Ting Lai, Dongjun Peng, Peter D. Kwong, Robert T. Bailer, Joseph Sodroski, Sijy O'Dell, John R. Mascola, Bob C. Lin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Diverse entry inhibitors targeting the gp120 subunit of the HIV-1 envelope (Env) trimer have been developed including BMS-626529, also called temsavir, a prodrug version of which is currently in phase III clinical trials. Here we report the character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1394cddbcc51ffdb4a9dba654998335e
https://doaj.org/article/8c1780f80cef41df909afde553e1a2ab
https://doaj.org/article/8c1780f80cef41df909afde553e1a2ab
Autor:
Yi Zhang, Masaru Kanekiyo, Yongping Yang, John R. Mascola, Baoshan Zhang, Crystal S.F. Cheung, Chen-Hsiang Shen, Tongqing Zhou, Barney S. Graham, M. Gordon Joyce, Eun Sung Yang, Reda Rawi, Adrian Creanga, Gwo-Yu Chuang, Lingshu Wang, Kwanyee Leung, Jason Gorman, Peter D. Kwong, Brandon J. DeKosky
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Sequence signatures of multidonor broadly neutralizing influenza antibodies can be used to quantify the prevalence of B cells with virus-neutralizing potential to accelerate development of broadly protective vaccine strategies. Antibodies of the same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7f83a9da81cb337e604b57e514cf1a
https://pubmed.ncbi.nlm.nih.gov/34135892
https://pubmed.ncbi.nlm.nih.gov/34135892
Autor:
Florian Krammer, Sarah F. Andrews, Kenta Matsuda, Peter D. Kwong, Stephen A. Migueles, Adam K. Wheatley, Sarah Stuccio, Sam Darko, Marc Gurwith, Mark Connors, Jinghe Huang, Baoshan Zhang, Robert T. Bailer, Trevor Griesman, M. Gordon Joyce, Zizhang Sheng, Jeff Alexander, Alyssa A. Pullano, Elise Ishida, Jason Plyler, Yaroslav Tsybovsky, Byong H. Kang, Teddy John Wohlbold, Hana Golding, Tongqing Zhou, Kwanyee Leung, Richard A. Koup, Jon Smith, Adrian B. McDermott, Surender Khurana, Lyuba Bolkhovitinov, Crystal S.F. Cheung, Cinque Soto, Yongping Yang, Yicheng Guo, Lawrence Shapiro, Veronika Chromikova, C. Jason Liang, Sandeep Narpala, April Poole, Alberto Cagigi
Publikováno v:
Science Immunology. 4
Induction of an antibody response capable of recognizing highly diverse strains is a major obstacle to the development of vaccines for viruses such as HIV and influenza. Here, we report the dynamics of B cell expansion and evolution at the single-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbb70ea554f5cb4b95d0cf15d6facdd
https://doi.org/10.1126/sciimmunol.aau2710
https://doi.org/10.1126/sciimmunol.aau2710
Autor:
Michal Ad, Julian C. Lui, Zhongyu Zhu, Max Colbert, Kevin M. Barnes, Audrey Lee, Dimiter S. Dimitrov, Crystal S.F. Cheung, Jeffrey Baron
Publikováno v:
Journal of the Endocrine Society
Recombinant human growth hormone (GH) is commonly used to treat short stature in children. However, GH treatment has limited efficacy particularly in severe, non-GH deficient conditions such as chondrodysplasias, and has potential off-target effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d918a9d44ea21156b022e53d1494d0
http://europepmc.org/articles/PMC6554759
http://europepmc.org/articles/PMC6554759
Publikováno v:
Analytical Chemistry. 87:1097-1102
Quantification by targeted proteomics has largely depended on mass spectrometry and isotope-labeled internal standards. In addition to traditionally used recombinant proteins or synthetic peptides, concatenated peptides (QconCATs) were introduced as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f027d28dc38f0b7ccb1cdab27b32d9
https://doi.org/10.1021/ac503697j
https://doi.org/10.1021/ac503697j
Autor:
Angela Delaney, Patricia Forcinito, Jeffrey Baron, Julian C. Lui, Crystal S.F. Cheung, Weiping Chen, Geoffrey Rezvani, Vasantha Padmanabhan
Publikováno v:
Journal of Molecular Endocrinology. 52:269-277
Body size varies enormously among mammalian species. In small mammals, body growth is typically suppressed rapidly, within weeks, whereas in large mammals, growth is suppressed slowly, over years, allowing for a greater adult size. We recently report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56be74bc13b9880a881f8eb608b65fa9
https://doi.org/10.1530/jme-13-0263
https://doi.org/10.1530/jme-13-0263
Publikováno v:
Journal of Orthopaedic Research. 31:1053-1058
As an initial step toward targeting cartilage tissue for potential therapeutic applications, we sought cartilage-binding peptides using phage display, a powerful technology for selection of peptides that bind to molecules of interest. A library of ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::037ce50d8560aa7e55e1f0bb82753dc3
https://doi.org/10.1002/jor.22325
https://doi.org/10.1002/jor.22325
Activity of the MEK inhibitor selumetinib (AZD6244; ARRY-142886) in nasopharyngeal cancer cell lines
Autor:
S. H. Cheng, Brigette B.Y. Ma, Patrick Kwok Shing Ng, Stephen Kwok-Wing Tsui, Cecilia P.Y. Lau, Sai Wai Tsao, Vivian Wai Yan Lui, Crystal S.F. Cheung, Edwin P. Hui, Kakiu Ho, Anthony T.C. Chan, Margaret H.L. Ng
Publikováno v:
Investigational New Drugs. 31:30-38
This study evaluated the preclinical activity of selumetinib (AZD6244, ARRY-142866), an inhibitor of the mitogen-activated protein kinase kinase (MAPKK or MEK1/2) in 6 nasopharyngeal cancer (NPC) cell lines. Selumetinib could achieve up to 90 % inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba65e0e3448888f273f34680b3418d1
https://doi.org/10.1007/s10637-012-9828-4
https://doi.org/10.1007/s10637-012-9828-4
Autor:
Akira Mita, Bo Hong, Yasundo Yamasaki, Sai Wah Tsao, Crystal S.F. Cheung, Vivian Wai Yan Lui, Suk Hang Cheng, Chi Man Tsang, Anthony T.C. Chan, Kakiu Ho, Cecilia Pik Yuk Lau, Margaret H.L. Ng, Kenny I.K. Lei
Publikováno v:
Biochemical Pharmacology. 79:1772-1780
1-(3-C-ethynyl-beta-d-ribo-pentofuranosyl)cytosine (ECyd) is a ribose-modified nucleoside analog of cytidine with potent anticancer activity in several cancers. The main antitumor mechanism of this promising RNA-directed nucleoside anti-metabolite is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92520942b71b978a7abc68671bfa2e7
https://doi.org/10.1016/j.bcp.2010.02.012
https://doi.org/10.1016/j.bcp.2010.02.012