Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Crystal Potter"'
Autor:
Emily M. Eshleman, Taylor Rice, Crystal Potter, Amanda Waddell, Seika Hashimoto-Hill, Vivienne Woo, Sydney Field, Laura Engleman, Michael A. Schumacher, Mark R. Frey, Lee A. Denson, Fred D. Finkelman, Theresa Alenghat
SUMMARYAllergy and anti-helminth immunity are driven by type 2 responses in mucosal tissues. Tuft cells are key regulators of type 2 immunity, however the factors that control these cells remain poorly understood. Here we find that butyrate-producing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e35628345137fe25b669b89bc7aa48f
https://doi.org/10.1101/2023.03.02.530792
https://doi.org/10.1101/2023.03.02.530792
Publikováno v:
Mucosal immunology
Airway hyperresponsiveness (AHR) often defines asthma. Murine allergic airway disease (AAD), like human eosinophilic asthma, is characterized by AHR, eosinophilia, goblet cell metaplasia (GCM), smooth muscle hypercontractility and increased productio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8191e62a5714473457d586c67aa40e34
https://doi.org/10.1038/s41385-019-0232-7
https://doi.org/10.1038/s41385-019-0232-7
Autor:
Marat Khodoun, Crystal Potter, Charles Perkins, Richard T. Strait, Richard Schuman, Fred D. Finkelman, Unni Samavedam, David Parsons, Suzanne C. Morris
Publikováno v:
J Allergy Clin Immunol
Background Administering allergens in increasing doses can temporarily suppress IgE-mediated allergy and anaphylaxis by desensitizing mast cells and basophils; however, allergen administration during desensitization therapy can itself induce allergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726da9f0117401d5fe3e058a82d31c68
https://europepmc.org/articles/PMC9187951/
https://europepmc.org/articles/PMC9187951/
Autor:
Elizabeth Angerman, Crystal Potter, Marat Khodoun, Artem Kiselev, Anna Otte, Alexander E. Yarawsky, Wen-Hai Shao, Katja Klausz, Matthias Peipp, Fred D. Finkelman, Suzanne C. Morris, Andrew B. Herr
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:1838-1854.e4
Background Mast cell and basophil activation by antigen cross-linking of FceRI-bound IgE is central to allergy pathogenesis. We previously demonstrated global suppression of this process by rapid desensitization with anti-FceRIα mAbs. Objectives We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7e5a77d6d49600390e9695f56bc9a8e
https://doi.org/10.1016/j.jaci.2020.10.045
https://doi.org/10.1016/j.jaci.2020.10.045
Autor:
Unni Krishna SRL Samavedam, Crystal Potter, Elizabeth Angerman, Anika Kasprick, Katja Bieber, Ralf Ludwig, Fred D Finkelman
Publikováno v:
The Journal of Immunology. 204:218.28-218.28
EBA is a chronic inflammatory, mucocutaneous blistering skin diseases caused by autoantibodies against the structural skin protein, COL7. EBA induction requires autoantibody binding as well as complement- and Fcγ receptor (FcγR)-dependent inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb2f84e7efdba6d890f1333a4386b9ae
https://doi.org/10.4049/jimmunol.204.supp.218.28
https://doi.org/10.4049/jimmunol.204.supp.218.28
Autor:
Marat Khodoun, Matthias Peipp, Suzanne C Morris, Elizabeth Angerman, Crystal Potter, Andrew Herr, James Mulloy, Mark Wunderlich, Fred D Finkelman
Publikováno v:
The Journal of Immunology. 204:66.22-66.22
Background Mast cells and FceRI, the high affinity IgE receptor (R), are central to allergy pathogenesis. Strong FceRI crosslinking induces severe allergy while low-level crosslinking removes IgE from mast cells and desensitizes them. Hypothesis IgE-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50cbc7725d086064fd4f5588d63d5834
https://doi.org/10.4049/jimmunol.204.supp.66.22
https://doi.org/10.4049/jimmunol.204.supp.66.22
Autor:
Charles Perkins, Lucy A. Gildea, Crystal Potter, Frank Brombacher, Marsha Wills-Karp, George Smulian, Bruce J. Aronow, Tatyana Orekov, Fred D. Finkelman, Noriko Yanase
Publikováno v:
The Journal of Experimental Medicine
IL-4Rα expression on airway smooth muscle cells is sufficient for the development of airway hyperresponsiveness.
Production of the cytokines IL-4 and IL-13 is increased in both human asthma and mouse asthma models, and Stat6 activation by the c
Production of the cytokines IL-4 and IL-13 is increased in both human asthma and mouse asthma models, and Stat6 activation by the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01da9331f7c6ec315c675a5819c3d2a9
http://europepmc.org/articles/PMC3135339
http://europepmc.org/articles/PMC3135339
Autor:
Unni Krishna SRL. Samavedam, Suzanne C. Morris, Marat Khodoun, David Wu, Crystal Potter, Simon P. Hogan, Fred D. Finkelman
Publikováno v:
The Journal of Immunology. 200:104.14-104.14
Murine food allergy induction and maintenance is promoted by increased epithelial permeability and requires the pro-Th2 cytokines: IL-25, IL-33, and TSLP, but how allergens increase permeability and induce pro-Th2 cytokines is unknown. Saturated fats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7b37e8a9cff51df91847753b6e22211
https://doi.org/10.4049/jimmunol.200.supp.104.14
https://doi.org/10.4049/jimmunol.200.supp.104.14
Publikováno v:
Journal of Allergy and Clinical Immunology. 139:AB263
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f09193779173674e4d0392b258f36e9f
https://doi.org/10.1016/j.jaci.2016.12.847
https://doi.org/10.1016/j.jaci.2016.12.847
Autor:
Marat Khodoun, Durga Krishnamurthy, Richard T Strait, Joel Tocker, Crystal Potter, Fred D Finkelman
Publikováno v:
The Journal of Immunology. 196:123.5-123.5
Food ingestion generally induces antigen (Ag)-specific tolerance rather than immunity. In contrast, we recently reported (JACI, 131:442–50, 2013) that Ag-specific, IgE-mediated food allergy (FA) can be induced when a protein Ag is repeatedly ingest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f254d0fb7bb9b54d3f4e2868b754ab2d
https://doi.org/10.4049/jimmunol.196.supp.123.5
https://doi.org/10.4049/jimmunol.196.supp.123.5