Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Crystal Pacut"'
Autor:
Sarah E. Elzinga, Rosemary Henn, Benjamin J. Murdock, Bhumsoo Kim, John M. Hayes, Faye Mendelson, Ian Webber-Davis, Sam Teener, Crystal Pacut, Stephen I. Lentz, Eva L. Feldman
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Obesity, prediabetes, and diabetes are growing in prevalence worldwide. These metabolic disorders are associated with neurodegenerative diseases, particularly Alzheimer’s disease and Alzheimer’s disease related dementias. Innate inflammatory sign
Externí odkaz:
https://doaj.org/article/9488b3682a0c4c8ea380c898b36a645c
Autor:
Claudia Figueroa-Romero, Alina Monteagudo, Benjamin J. Murdock, Joshua P. Famie, Ian F. Webber-Davis, Caroline E. Piecuch, Samuel J. Teener, Crystal Pacut, Stephen A. Goutman, Eva L. Feldman
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disease with few therapeutic options. However, the immune system, including natural killer (NK) cells, is linked to ALS progression and may constitute a viable therapeutic
Externí odkaz:
https://doaj.org/article/cdef3182937949c9b103a09cb74c1f06
Autor:
Ting-wen Lo, Claudia Figueroa-Romero, Junguk Hur, Crystal Pacut, Evan Stoll, Calvin Spring, Rose Lewis, Athul Nair, Stephen A. Goutman, Stacey A. Sakowski, Sunitha Nagrath, Eva L. Feldman
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Amyotrophic lateral sclerosis (ALS) is a terminalneurodegenerative disease. Clinical and molecular observations suggest that ALS pathology originates at a single site and spreads in an organized and prion-like manner, possibly driven by extracellular
Externí odkaz:
https://doaj.org/article/096cc19ce0b6428abc876d39c85f314d
Autor:
Kai Guo, Sarah Elzinga, Stephanie Eid, Claudia Figueroa-Romero, Lucy M. Hinder, Crystal Pacut, Eva L. Feldman, Junguk Hur
Publikováno v:
Epigenetics, Vol 14, Iss 8, Pp 766-779 (2019)
DNA methylation is an epigenetic mechanism important for the regulation of gene expression, which plays a vital role in the interaction between genetic and environmental factors. Aberrant epigenetic changes are implicated in the pathogenesis of diabe
Externí odkaz:
https://doaj.org/article/ff7f57880800477aba718930fa659f0e
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009445 (2021)
Expansion of the hexanucleotide repeat (HR) in the first intron of the C9orf72 gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in Caucasians. All C9orf72-ALS/FTD patients share a common r
Externí odkaz:
https://doaj.org/article/be2976136eec4a4eb294ed7d3cbeb49a
Autor:
J. Simon Lunn, Crystal Pacut, Emily Stern, Stacey A. Sakowski, J. Matthew Velkey, Sue O'Shea, Eva L. Feldman
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 1, Pp 59-68 (2012)
Embryonic stem (ES) cells and their derivatives are an important resource for developing novel cellular therapies for disease. Controlling proliferation and lineage selection, however, are essential to circumvent the possibility of tumor formation an
Externí odkaz:
https://doaj.org/article/deb611ceabb740ed83374316faebe479
Autor:
Claudia, Figueroa-Romero, Alina, Monteagudo, Benjamin J, Murdock, Joshua P, Famie, Ian F, Webber-Davis, Caroline E, Piecuch, Samuel J, Teener, Crystal, Pacut, Stephen A, Goutman, Eva L, Feldman
Publikováno v:
Frontiers in immunology. 13
Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disease with few therapeutic options. However, the immune system, including natural killer (NK) cells, is linked to ALS progression and may constitute a viable therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3328371dee4d42491cf37b7f82d7e3d7
https://pubmed.ncbi.nlm.nih.gov/35197969
https://pubmed.ncbi.nlm.nih.gov/35197969
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009445 (2021)
PLoS Genetics
PLoS Genetics
Expansion of the hexanucleotide repeat (HR) in the first intron of the C9orf72 gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in Caucasians. All C9orf72-ALS/FTD patients share a common r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb3ab0116a8b10e46772972c38720b3
https://doaj.org/article/be2976136eec4a4eb294ed7d3cbeb49a
https://doaj.org/article/be2976136eec4a4eb294ed7d3cbeb49a
Publikováno v:
Clinical Epigenetics
Diabetic peripheral neuropathy (DPN) is the most common complication of type 2 diabetes (T2D). Although the cellular and molecular mechanisms of DPN are poorly understood, we and others have shown that altered gene expression and DNA methylation are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23484276b0b6e5a38cc78d86b69221d5
https://doi.org/10.1186/s13148-020-00922-5
https://doi.org/10.1186/s13148-020-00922-5
Publikováno v:
Clinical Epigenetics
Background Diabetic peripheral neuropathy (DPN) is the most common complication of type 2 diabetes (T2D). Although the cellular and molecular mechanisms of DPN are poorly understood, we and others have shown that altered gene expression and DNA methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0bcd64bb1b1e28754de378914458fdb
https://doi.org/10.1186/s13148-020-00913-6
https://doi.org/10.1186/s13148-020-00913-6