Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Crystal Meyerett"'
Autor:
Crystal Meyerett-Reid, A. Christy Wyckoff, Terry Spraker, Bruce Pulford, Heather Bender, Mark D. Zabel
Publikováno v:
mSphere, Vol 2, Iss 1 (2017)
ABSTRACT Substantial evidence supports the hypothesis that prions are misfolded, infectious, insoluble, and protease-resistant proteins (PrPRES) devoid of instructional nucleic acid that cause transmissible spongiform encephalopathies (TSEs). Protein
Externí odkaz:
https://doaj.org/article/223966d16ccb44c693a8127d11af7d11
Autor:
Tracy A Nichols, Terry R Spraker, Tara D Rigg, Crystal Meyerett-Reid, Clare Hoover, Brady Michel, Jifeng Bian, Edward Hoover, Thomas Gidlewski, Aru Balachandran, Katherine O'Rourke, Glenn C Telling, Richard Bowen, Mark D Zabel, Kurt C VerCauteren
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62455 (2013)
Chronic wasting disease (CWD), the only known prion disease endemic in wildlife, is a persistent problem in both wild and captive North American cervid populations. This disease continues to spread and cases are found in new areas each year. Indirect
Externí odkaz:
https://doaj.org/article/519cd09084264ef8ab5eac16275fdefe
Autor:
A Christy Wyckoff, Krista L Lockwood, Crystal Meyerett-Reid, Brady A Michel, Heather Bender, Kurt C VerCauteren, Mark D Zabel
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58630 (2013)
Prions, the infectious agent of scrapie, chronic wasting disease and other transmissible spongiform encephalopathies, are misfolded proteins that are highly stable and resistant to degradation. Prions are known to associate with clay and other soil c
Externí odkaz:
https://doaj.org/article/bc80ae06a9ab4efe8d8d1eaa208e04e4
Autor:
Bruce Pulford, Natalia Reim, Aimee Bell, Jessica Veatch, Genevieve Forster, Heather Bender, Crystal Meyerett, Scott Hafeman, Brady Michel, Theodore Johnson, A Christy Wyckoff, Gino Miele, Christian Julius, Jan Kranich, Alan Schenkel, Steven Dow, Mark D Zabel
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11085 (2010)
BACKGROUND: Recent advances toward an effective therapy for prion diseases employ RNA interference to suppress PrP(C) expression and subsequent prion neuropathology, exploiting the phenomenon that disease severity and progression correlate with host
Externí odkaz:
https://doaj.org/article/99c0316e98244a38b8b1bf802eac1cb8
Autor:
Joaquín Castilla, Vadim Khaychuk, Jifeng Bian, Glenn C. Telling, Enric Vidal, Jason C. Bartz, Umberto Agrimi, Rachel Angers, Natalia Fernández-Borges, Crystal Meyerett-Reid, Edward A. Hoover, Jürgen A. Richt, Carla Calvi, Sehun Kim
Publikováno v:
Proceedings of the National Academy of Sciences. 114:1141-1146
Adaptation of prions to new species is thought to reflect the capacity of the host-encoded cellular form of the prion protein (PrPC) to selectively propagate optimized prion conformations from larger ensembles generated in the species of origin. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1550dcfd7b58588e67618d11322a37
https://doi.org/10.1073/pnas.1611891114
https://doi.org/10.1073/pnas.1611891114
Autor:
Crystal Meyerett-Reid, Glenn C. Telling, A. Christy Wyckoff, Bruce Pulford, Heather Bender, Mark D. Zabel, Brady Michel, Theodore Johnson, Adam Ferguson
Publikováno v:
International Immunology. 25:697-702
Accumulating evidence shows a critical role of the complement system in facilitating attachment of prions to both B cells and follicular dendritic cells and assisting in prion replication. Complement activation intensifies disease in prion-infected a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835d7f0f57b6c0fe6647863a01b1fe56
https://doi.org/10.1093/intimm/dxt034
https://doi.org/10.1093/intimm/dxt034
Autor:
Krista Lockwood, Glenn C. Telling, Heather Bender, Crystal Meyerett, Bruce Pulford, Margaret A. Wild, Jenny G. Powers, Brittney Wyatt, Adam Ferguson, Mark D. Zabel, Terry R. Spraker, A. Christy Wyckoff
Publikováno v:
Journal of Wildlife Diseases. 48:425-434
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy affecting captive and free-ranging cervids. Currently, tests for CWD in live animals involve relatively invasive procedures to collect lymphoid tissue biopsies and examine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a5eb78097085f47a4cb379457239a5
https://doi.org/10.7589/0090-3558-48.2.425
https://doi.org/10.7589/0090-3558-48.2.425
Autor:
Kurt C. VerCauteren, A. Christy Wyckoff, Terry R. Spraker, Michael F. Antolin, Margaret A. Wild, Ryan J. Monello, Mark D. Zabel, Jenny G. Powers, Crystal Meyerett-Reid, Bruce Pulford, Nathan L. Galloway
Publikováno v:
Scientific Reports
Prions are unique infectious agents that replicate without a genome and cause neurodegenerative diseases that include chronic wasting disease (CWD) of cervids. Immunohistochemistry (IHC) is currently considered the gold standard for diagnosis of a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1ea1b642af1416c03d17d9ae7b847c
Autor:
Brady Michel, Adam Ferguson, Glenn C. Telling, Theodore Johnson, Davis M. Seelig, Mark D. Zabel, Crystal Meyerett-Reid, Heather Bender, Adriano Aguzzi, John H. Weis, Bruce Pulford, Adriana von Teichman
Publikováno v:
The Journal of Immunology
The complement system has been shown to facilitate peripheral prion pathogenesis. Mice lacking complement receptors CD21/35 partially resist terminal prion disease when infected i.p. with mouse-adapted scrapie prions. Chronic wasting disease (CWD) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab19e4760afd8fc5d3ebb0c53a59d0b9
https://europepmc.org/articles/PMC3478448/
https://europepmc.org/articles/PMC3478448/
Autor:
Glenn C. Telling, Crystal Meyerett-Reid, Brady Michel, Heather Bender, Theodore Johnson, Steven W. Dow, Bruce Pulford, A. Christy Wyckoff, Mark D. Zabel, Adam Ferguson, Anne C. Avery
Publikováno v:
Scientific Reports
While prions probably interact with the innate immune system immediately following infection, little is known about this initial confrontation. Here we investigated incunabular events in lymphotropic and intranodal prion trafficking by following high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468417880b96a39ca93cfcfd8342ef51
https://doi.org/10.1038/srep00440
https://doi.org/10.1038/srep00440