Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Crystal M. Wilkie"'
Autor:
Crystal M. Wilkie, Jessica C. Barron, Kyle J. Brymer, Jocelyn R. Barnes, Firoozeh Nafar, Matthew P. Parsons
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Pharmacological upregulation of glutamate transporter-1 (GLT-1), commonly achieved using the beta-lactam antibiotic ceftriaxone, represents a promising therapeutic strategy to accelerate glutamate uptake and prevent excitotoxic damage in neurological
Externí odkaz:
https://doaj.org/article/304020b4c0d9474aa0a9f6418a7d4637
Autor:
Kyle J Brymer, Jessica C Barron, Firoozeh Nafar, Matthew P. Parsons, Crystal M Wilkie, Jocelyn R. Barnes
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Pharmacological upregulation of glutamate transporter-1 (GLT-1), commonly achieved using the beta-lactam antibiotic ceftriaxone, represents a promising therapeutic strategy to accelerate glutamate uptake and prevent excitotoxic damage in neurological
Publikováno v:
The Journal of Neuroscience. 38:5351-5366
Transporter-mediated glutamate uptake plays an essential role in shaping synaptic neurotransmission. The rapid removal of synaptically released glutamate ensures the high temporal dynamics characteristic of fast excitatory chemical neurotransmission
Autor:
Firoozeh Nafar, Cherry-Lynn M. Benson, Jocelyn R. Barnes, Kyle J. Brymer, Crystal M. Wilkie, Matthew P. Parsons
Publikováno v:
eNeuro
Glutamate transporters, particularly glutamate transporter 1 (GLT-1), help to prevent the adverse effects associated with glutamate toxicity by rapidly clearing glutamate from the extracellular space. Since GLT-1 expression and/or function are reduce