Výsledky vyhledávání - "Crystal M Vincent"

Akademický článek

Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster.

Autor: Crystal M Vincent, Esteban J Beckwith, Carolina J Simoes da Silva, William H Pearson, Katrin Kierdorf, Giorgio F Gilestro, Marc S Dionne

Publikováno v: PLoS Pathogens, Vol 18, Iss 9, p e1010826 (2022)

Host behavioural changes are among the most apparent effects of infection. 'Sickness behaviour' can involve a variety of symptoms, including anorexia, depression, and changed activity levels. Here, using a real-time tracking and behavioural profiling

Externí odkaz: https://doaj.org/article/4d39238a1b314f91bfe654c56671cdb7

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Akademický článek

Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila

Autor: Katrin Kierdorf, Fabian Hersperger, Jessica Sharrock, Crystal M Vincent, Pinar Ustaoglu, Jiawen Dou, Attila Gyoergy, Olaf Groß, Daria E Siekhaus, Marc S Dionne

Publikováno v: eLife, Vol 9 (2020)

Unpaired ligands are secreted signals that act via a GP130-like receptor, domeless, to activate JAK/STAT signalling in Drosophila. Like many mammalian cytokines, unpaireds can be activated by infection and other stresses and can promote insulin resis

Externí odkaz: https://doaj.org/article/cfd49166d2854e07bbaa0911e97a29c0

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Akademický článek

Origins of Metabolic Pathology in Francisella-Infected Drosophila

Autor: Crystal M. Vincent, Carolina J. Simoes da Silva, Ashima Wadhawan, Marc S. Dionne

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

The origins and causes of infection pathologies are often not understood. Despite this, the study of infection and immunity relies heavily on the ability to discern between potential sources of pathology. Work in the fruit fly has supported the assum

Externí odkaz: https://doaj.org/article/deb93de7edf04f8d8edc4576d37c1f28

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Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster

Autor: Marc Dionne, Crystal M. Vincent, Esteban J. Beckwith, Giorgio F. Gilestro, Katrin Kierdorf, William H. Pearson

Host behavioural changes are among the most apparent effects of infection. ‘Sickness behaviour’ can involve a variety of symptoms, including anorexia, depression, and changed activity levels. Here we use a real-time tracking and behavioural profi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98a1ce24b413b19051acabf1dacab8bc
https://doi.org/10.1101/2021.08.24.457493

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Disparate regulation of IMD signaling drives sex differences in infection pathology in Drosophila melanogaster

Autor: Crystal M. Vincent, Marc Dionne

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance Sex differences in infection outcome are a widely observed phenomenon. While it is known that biological sex can influence an animal’s response to infection, the mechanisms through which these differences emerge are less clear. Here, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bf1999c65f2f5133603569a8c316da
https://doi.org/10.1073/pnas.2026554118

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Disparate regulation of imd drives sex differences in infection pathology in Drosophila melanogaster

Autor: Marc Dionne, Crystal M. Vincent

Male and female animals exhibit differences in infection outcomes. One possible source of sexually dimorphic immunity is sex-specific costs of immune activity or pathology, but little is known about the independent effects of immune-induced versus mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e142b402da7b21c7b53189533696336
https://doi.org/10.1101/2020.08.12.247965

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