Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Crystal J. J. Lee"'
Autor:
Crystal J. J. Lee, Rashid Abu-Ghazalah, Julia Perstin, Thomas R. Einarson, Adrienne Einarson, Jennifer Manley, Payam Zahedi, Ryan W. Smith, Margaret M. Loniewska
Publikováno v:
Birth Defects Research Part A: Clinical and Molecular Teratology. 76:621-628
BACKGROUND: Most clinicians read only the abstract of papers in scientific journals. Therefore, it is very important that abstracts contain as much information as possible, to summarize the data succinctly. Our objectives were to evaluate the quality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca85b6995e86668fafb2ed4332dc06c3
https://doi.org/10.1002/bdra.20289
https://doi.org/10.1002/bdra.20289
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 122(1)
Thalidomide (TD) displays remarkable species specificity, causing birth defects (teratogenesis) in humans and rabbits, but not rats or mice; yet, few determinants of species susceptibility have been identified. Also, certain mouse strains are suscept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5e21036256e6f4448bd531174f498c
https://pubmed.ncbi.nlm.nih.gov/21505090
https://pubmed.ncbi.nlm.nih.gov/21505090
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 122(1)
The expanding therapeutic uses of thalidomide (TD) are limited by its teratogenic side effects. Although the therapeutic and teratogenic effects may be stereoselectively separable, rapid in vivo racemization of the TD isomers confounds the corroborat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb470e9b61a74f122b721b158f20ad2
https://pubmed.ncbi.nlm.nih.gov/21505091
https://pubmed.ncbi.nlm.nih.gov/21505091
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25(7)
Thalidomide (TD) causes birth defects in humans and rabbits via several potential mecha- nisms, including bioactivation by embryonic prostaglan- din H synthase (PHS) enzymes to a reactive intermedi- ate that enhances reactive oxygen species (ROS) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02e56f8e12164fe4d2a3bf79220c390
https://pubmed.ncbi.nlm.nih.gov/21502285
https://pubmed.ncbi.nlm.nih.gov/21502285
Publikováno v:
Handbook of experimental pharmacology. (196)
Drugs and environmental chemicals can adversely alter the development of the fetus at critical periods during pregnancy, resulting in death, or in structural and functional birth defects in the surviving offspring. This process of teratogenesis may n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04a6b55aaa0b5e65f5b110516231ee44
https://pubmed.ncbi.nlm.nih.gov/20020262
https://pubmed.ncbi.nlm.nih.gov/20020262
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642006623
Drugs and environmental chemicals can adversely alter the development of the fetus at critical periods during pregnancy, resulting in death, or in structural and functional birth defects in the surviving offspring. This process of teratogenesis may n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25fc5085ed9136a83b948a5a53c12475
https://doi.org/10.1007/978-3-642-00663-0_6
https://doi.org/10.1007/978-3-642-00663-0_6
Autor:
Jeffrey T. Henderson, Andrea W. Wong, Julia Perstin, Connie S. Chen, Michael J. Wiley, Thomas J. Preston, Crystal J. J. Lee, Peter G. Wells, Gordon P. McCallum
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 108(1)
In the developing embryo and fetus, endogenous or xenobiotic-enhanced formation of reactive oxygen species (ROS) like hydroxyl radicals may adversely alter development by oxidatively damaging cellular lipids, proteins and DNA, and/or by altering sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6d2e1829c538a4041524e1dd6412cb
https://pubmed.ncbi.nlm.nih.gov/19126598
https://pubmed.ncbi.nlm.nih.gov/19126598
Autor:
Peter G. Wells, Gordon P. McCallum, Connie S. Chen, Jeffrey T. Henderson, Crystal J. J. Lee, Julia Perstin, Thomas J. Preston, Michael J. Wiley, Andrea W. Wong
Publikováno v:
Toxicological Sciences; Mar2009, Vol. 108 Issue 1, p4-4, 1p