Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Crystal C. Lipsey"'
Autor:
Crystal C. Lipsey, Adriana Harbuzariu, Robert W. Robey, Lyn M. Huff, Michael M. Gottesman, Ruben R. Gonzalez-Perez
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3794 (2020)
Estrogen-receptor-negative breast cancer (BCER−) is mainly treated with chemotherapeutics. Leptin signaling can influence BCER− progression, but its effects on patient survival and chemoresistance are not well understood. We hypothesize that lept
Externí odkaz:
https://doaj.org/article/807e54c44ed241e89a95c83e42814e60
Autor:
George Alyateem, Heidi M. Wade, Aaron A. Bickert, Crystal C. Lipsey, Priya Mondal, MacKinzie D. Smith, Rania M. Labib, Beverly A. Mock, Robert W. Robey, Michael M. Gottesman
Publikováno v:
Cancer Gene Therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6369cc351ab125811a9c7b3d2b8a71c3
https://doi.org/10.1038/s41417-023-00608-z
https://doi.org/10.1038/s41417-023-00608-z
Autor:
Robert W. Robey, Christina M. Fitzsimmons, Wilfried M. Guiblet, William J.E. Frye, José M. González Dalmasy, Li Wang, Drake A. Russell, Lyn M. Huff, Andrew J. Perciaccante, Fatima Ali-Rahmani, Crystal C. Lipsey, Heidi M. Wade, Allison V. Mitchell, Siddhardha S. Maligireddy, David Terrero, Donna Butcher, Elijah F. Edmondson, Lisa M. Jenkins, Tatiana Nikitina, Victor B. Zhurkin, Amit K. Tiwari, Anthony D. Piscopio, Rheem A. Totah, Susan E. Bates, H. Efsun Arda, Michael M. Gottesman, Pedro J. Batista
Histone deacetylase inhibitors (HDACis) are part of a growing class of epigenetic therapies used for the treatment of cancer. While elevated levels of the efflux pump P-gp are associated within vitroresistance to romidepsin, this mechanism does not t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eab6c73a6fa5f6f5baa893e9093b0da
https://doi.org/10.1101/2022.10.07.511310
https://doi.org/10.1101/2022.10.07.511310
Autor:
Robert W. Robey, Crystal C Lipsey, Lyn M. Huff, Michael M. Gottesman, Adriana Harbuzariu, Ruben R. Gonzalez-Perez
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3794, p 3794 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 11
International Journal of Molecular Sciences
Volume 21
Issue 11
Estrogen-receptor-negative breast cancer (BCER&minus
) is mainly treated with chemotherapeutics. Leptin signaling can influence BCER&minus
progression, but its effects on patient survival and chemoresistance are not well understood. We hypo
) is mainly treated with chemotherapeutics. Leptin signaling can influence BCER&minus
progression, but its effects on patient survival and chemoresistance are not well understood. We hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ea2fe4ae8d65e548532598dbaf5dfd
https://www.mdpi.com/1422-0067/21/11/3794
https://www.mdpi.com/1422-0067/21/11/3794
Autor:
Lily Yang, Adriana Harbuzariu, Ruben R. Gonzalez-Perez, Ward Kirlin, Viola Lanier, Tia L. Harmon, Crystal C. Lipsey
Publikováno v:
World Journal of Clinical Oncology
Aim To develop a leptin peptide receptor antagonist linked to nanoparticles and determine its effect on viability of breast cancer cells. Methods The leptin antagonist, LPrA2, was coupled via EDAC [1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide] to ir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710a76f3995f32dc6c30b1fa14324a73
https://pubmed.ncbi.nlm.nih.gov/28246585
https://pubmed.ncbi.nlm.nih.gov/28246585
Autor:
Sha'Kayla Nunez, Viola Lanier, Ann Anu Kurian, Danielle Daley-Brown, Adriana Harbuzariu, Ruben R. Gonzalez, Tia L. Harmon, Crystal C. Lipsey
Publikováno v:
Molecular Cancer Therapeutics. 17:B046-B046
Obesity is pandemic and linked to higher incidence and poorer prognosis of several cancers, including pancreatic cancer (PC), triple-negative breast cancer (TNBC), and endometrial cancer type II (EmCa), which do not have targeted therapy. Commonly, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27c5a46fd3cfeede6be15da241360303
https://doi.org/10.1158/1535-7163.targ-17-b046
https://doi.org/10.1158/1535-7163.targ-17-b046
Autor:
Gale W. Newman, Crystal C. Lipsey, Joy Milner, Johannes Waltenberger, Danielle Daley-Brown, Ruben R. Gonzalez-Perez, Viola Lanier, Leonard M. Anderson, Merle Leffers, Corey Gillespie, Nia Webb
Publikováno v:
The international journal of biochemistrycell biology. 79
Leptin increases vascular endothelial growth factor (VEGF), VEGF receptor-2 (VEGFR-2), and Notch expression in cancer cells, and transphosphorylates VEGFR-2 in endothelial cells. However, the mechanisms involved in leptin's actions in endothelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc469ca9db6847339995d106a7f9dc37
https://pubmed.ncbi.nlm.nih.gov/27590851
https://pubmed.ncbi.nlm.nih.gov/27590851
Publikováno v:
Cancer Research. 77:3544-3544
Background: Pancreatic cancer (PC) has consistently been the fourth cancer-related cause of death in United States for more than 10 years. Its dismal prognosis is due to the aggressive behavior, late detection, lack of reliable biomarkers and low res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77d4b4d673247a40aa8b46023bfb7647
https://doi.org/10.1158/1538-7445.am2017-3544
https://doi.org/10.1158/1538-7445.am2017-3544
Publikováno v:
Cancer Research. 77:3540-3540
Obesity is a global health issue that has been identified as a risk factor for several types of cancer. High levels of body fat and circulating leptin are typical identifiers of obesity in humans and animals. Leptin is a 16kD protein hormone which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2fad102c7f20e19df9c1513b00e1142
https://doi.org/10.1158/1538-7445.am2017-3540
https://doi.org/10.1158/1538-7445.am2017-3540
Autor:
Shakeyla Nunez, Viola Lanier, Pierre V. Candelaria, Cynthia Tchio, Adriana Harbuzariu, Ruben R. Gonzalez-Perez, Antonio Rampoldi, Danielle Daley-Brown, McKay Mullen, Tia L. Harmon, Courtney D. Dill, Crystal C. Lipsey, Ann Anu Kurian
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 26:B66-B66
Obesity incidence has reached alarming levels, particularly in minority populations: African American (AA) and Latinos. The risk of develop several cancers (i.e., breast, pancreatic and endometrial cancers) is strongly correlated to obesity. One of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99ac4b7b53fa3bfc28b6aa7bb1d46c84
https://doi.org/10.1158/1538-7755.disp16-b66
https://doi.org/10.1158/1538-7755.disp16-b66