Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Crystal C Walline"'
Autor:
Gail J Gardiner, Sarah N Deffit, Shawna eMcLetchie, Liliana ePérez, Crystal C Walline, Janice S Blum
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase expressed in phagocytes is a multi-subunit enzyme complex that generates superoxide (O2.-). This radical is an important precursor of hydrogen peroxide (H2O2) and other reactive oxygen s
Externí odkaz:
https://doaj.org/article/00925d87b48b4dbbad61dd66c53af474
Autor:
Crystal C Walline, Sarita Sehra, Amanda J Fisher, Lynette M Guindon, Ian M Kratzke, Jessica B Montgomery, Kelsey P Lipking, Nicole L Glosson, Heather L Benson, George E Sandusky, David S Wilkes, Randy R Brutkiewicz, Mark H Kaplan, Janice S Blum
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62222 (2013)
Pulmonary viral infections can exacerbate or trigger the development of allergic airway diseases via multiple mechanisms depending upon the infectious agent. Respiratory vaccinia virus transmission is well established, yet the effects of allergic air
Externí odkaz:
https://doaj.org/article/aeae8b837aed456188f404888bdb4089
Publikováno v:
Journal of Investigative Medicine. 66:1-4
Excessive drinking can lead to the development of immune dysfunction. Our aim is to investigate the effect of alcohol on immune activation from circulating peripheral blood monocytes in excessive drinkers (EDs). Twenty-two EDs and healthy controls we
Autor:
Mark H. Kaplan, Kristin Hollister, Duy Pham, Janice S. Blum, Anthony B. Firulli, Crystal C. Walline, Alexander L. Dent
Publikováno v:
Journal of Biological Chemistry. 288:27423-27433
Cytokine responsiveness is a critical component of the ability of cells to respond to the extracellular milieu. Transcription factor-mediated regulation of cytokine receptor expression is a common mode of altering responses to the external environmen
Autor:
Rajarajeswari Muthukrishnan, Janice S. Blum, Qing Yu, Mark H. Kaplan, Duy Pham, Crystal C. Walline
Publikováno v:
The Journal of Immunology. 191:902-911
The STAT transcription factor STAT4 is a critical regulator of Th1 differentiation and inflammatory disease. Yet, how STAT4 regulates gene expression is still unclear. In this report, we define a STAT4-dependent sequence of events including histone H
Autor:
Caiqing Mo, Eli Casalini, Saravanan Kanakasabai, Crystal C. Walline, John J. Bright, Wanida Chearwae
Publikováno v:
The Open Autoimmunity Journal. 3:17-28
Publikováno v:
Brain Research. 1376:101-112
Multiple sclerosis (MS) is a neurological disorder that affects more than a million people worldwide. The etiology of MS is not known and there is no medical treatment that can cure MS. Earlier studies have shown that peroxisome proliferator-activate
Autor:
Suzanne M. Adams, Crystal C. Walline, Saravanan Kanakasabai, Wade T. Iams, Wanida Chearwae, John J. Bright
Publikováno v:
Immunology. 130:572-588
Multiple sclerosis (MS) is a neurological disorder that affects more than a million people world-wide. The aetiology of MS is not known and there is no medical treatment available that can cure MS. Experimental autoimmune encephalomyelitis (EAE) is a
Autor:
Seth R. Good, John T. O'Malley, Suzanne M. Adams, Mark H. Kaplan, Saravanan Kanakasabai, Wanida Chearwae, Caiqing Mo, John J. Bright, Crystal C. Walline, Gretta L. Stritesky, Narayanan B. Perumal
Publikováno v:
The Journal of Immunology. 181:5681-5690
Experimental allergic encephalomyelitis (EAE) is a T cell-mediated autoimmune disease model of multiple sclerosis. Signal transducer and activator of transcription 4 (Stat4) is a transcription factor activated by IL-12 and IL-23, two cytokines known
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 325:791-800
The human serotonin transporter (hSERT) regulates the spatial and temporal actions of serotonin (5-HT) neurotransmission by removing 5-HT from the synapse. Previous studies have identified residues in the third transmembrane helix (TMH) that may be i