Effect of synthetic betulinic acid derivatives on mitochondrial membrane potential (ΔΨm) in Plasmodium falciparum strains

Autor: DC Schuck, Nrg Maria, Grace Gosmann, AM Innocente, Gns Silva, M Nakabashi, Scb Gnoatto, Crs Garcia

Publikováno v: Planta Medica. 78

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b6b319a877b7a2314468a5b2aba7d1a
https://doi.org/10.1055/s-0032-1320370

A Plasmodium falciparum MORC protein complex modulates epigenetic control of gene expression through interaction with heterochromatin.

Autor: Singh MK; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Bonnell VA; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Harrisburg, United States.; Huck Institutes Center for Eukaryotic Gene Regulation, Pennsylvania State University, University Park, Harrisburg, United States.; Huck Institutes Center for Malaria Research, Pennsylvania State University, University Park, Harrisburg, United States., Tojal Da Silva I; Hospital AC Camargo, Centro Internacional de Pesquisa, São Paulo, Brazil., Santiago VF; Department of Parasitology, Institute of Biomedical Science, University of São Paulo, São Paulo, Brazil., Moraes MS; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Adderley J; School of Health and Biomedical Sciences, RMIT University, Bundoora, Australia., Doerig C; School of Health and Biomedical Sciences, RMIT University, Bundoora, Australia., Palmisano G; Department of Parasitology, Institute of Biomedical Science, University of São Paulo, São Paulo, Brazil., Llinas M; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Harrisburg, United States.; Huck Institutes Center for Eukaryotic Gene Regulation, Pennsylvania State University, University Park, Harrisburg, United States.; Huck Institutes Center for Malaria Research, Pennsylvania State University, University Park, Harrisburg, United States.; Department of Chemistry, Pennsylvania State University, University Park, Harrisburg, United States., Garcia CRS; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.

Publikováno v: ELife [Elife] 2024 Oct 16; Vol. 12. Date of Electronic Publication: 2024 Oct 16.

Editorial overview: Modern approaches to dissect host-pathogen interactions.

Autor: Silva-Filho MC; Department of Genetics-ESALQ-University of São Paulo, Brazil., Garcia CRS; Department of Clinical and Toxicological Analyses-FCF-University of São Paulo, Brazil.

Publikováno v: Current research in microbial sciences [Curr Res Microb Sci] 2023 Jul 12; Vol. 5, pp. 100197. Date of Electronic Publication: 2023 Jul 12 (Print Publication: 2023).

Combining IP 3 affinity chromatography and bioinformatics reveals a novel protein-IP 3 binding site on Plasmodium falciparum MDR1 transporter.

Autor: Alves E; Life Science Department, Imperial College London, London, United Kingdom., Nakaya H; Department of Clinical and Toxicological Analyses of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.; Computational Systems Biology Laboratory, INOVA, University of Sao Paulo, Sao Paulo, Brazil., Guimarães E; Federal University of Rio Grande do Norte, Pharmacy Department, Health Science Center, Natal, Brazil., Garcia CRS; Department of Clinical and Toxicological Analyses of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.

Publikováno v: Current research in microbial sciences [Curr Res Microb Sci] 2022 Dec 18; Vol. 4, pp. 100179. Date of Electronic Publication: 2022 Dec 18 (Print Publication: 2023).

Contribution of Transcriptome to Elucidate the Biology of Plasmodium spp.

Autor: Parreira KS; Departamento de Medicina, Instituto de Biotecnologia-Universidade Federal de Catalão, Catalão, Goiás, Brazil., Scarpelli P; Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo - USP, São Paulo, Brazil., Rezende Lima W; Departamento de Medicina, Instituto de Biotecnologia-Universidade Federal de Catalão, Catalão, Goiás, Brazil., Garcia CRS; Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo - USP, São Paulo, Brazil.

Publikováno v: Current topics in medicinal chemistry [Curr Top Med Chem] 2022; Vol. 22 (3), pp. 169-187.