Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Croucher PI"'
Autor:
Grootveld, AK, Kyaw, W, Panova, V, Lau, AWY, Ashwin, E, Seuzaret, G, Dhenni, R, Bhattacharyya, ND, Khoo, WH, Biro, M, Mitra, T, Meyer-Hermann, M, Bertolino, P, Tanaka, M, Hume, DA, Croucher, PI, Brink, R, Nguyen, A, Bannard, O, Phan, TG
Publikováno v:
Cell. 186:1144-1161.e18
Germinal centers (GCs) that form within lymphoid follicles during antibody responses are sites of massive cell death. Tingible body macrophages (TBMs) are tasked with apoptotic cell clearance to prevent secondary necrosis and autoimmune activation by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e8ece1063f6f8b6d2b7585ea489387
https://doi.org/10.1016/j.cell.2023.02.004
https://doi.org/10.1016/j.cell.2023.02.004
Autor:
Morris, JA, Kemp, JP, Youlten, SE, Laurent, L, Logan, JG, Chai, RC, Vulpescu, NA, Forgetta, V, Kleinman, A, Mohanty, ST, Sergio, CM, Quinn, J, Nguyen-Yamamoto, L, Luco, A-L, Vijay, J, Simon, M-M, Pramatarova, A, Medina-Gomez, C, Trajanoska, K, Ghirardello, EJ, Butterfield, NC, Curry, KF, Leitch, VD, Sparkes, PC, Adoum, A-T, Mannan, NS, Komla-Ebri, DSK, Pollard, AS, Dewhurst, HF, Hassall, TAD, Beltejar, M-JG, Agee, M, Alipanahi, B, Auton, A, Bell, RK, Bryc, K, Elson, SL, Fontanillas, P, Furlotte, NA, McCreight, JC, Huber, KE, Litterman, NK, McIntyre, MH, Mountain, JL, Noblin, ES, Northover, CAM, Pitts, SJ, Sathirapongsasuti, JF, Sazonova, OV, Shelton, JF, Shringarpure, S, Tian, C, Tung, JY, Vacic, V, Wilson, CH, Adams, DJ, Vaillancourt, SM, Kaptoge, S, Baldock, P, Cooper, C, Reeve, J, Ntzani, EE, Evangelou, E, Ohlsson, C, Karasik, D, Rivadeneira, F, Kiel, DP, Tobias, JH, Gregson, CL, Harvey, NC, Grundberg, E, Goltzman, D, Lelliott, CJ, Hinds, DA, Ackert-Bicknell, CL, Hsu, Y-H, Maurano, MT, Croucher, PI, Williams, GR, Bassett, JHD, Evans, DM, Richards, JB
Publikováno v:
Nature Genetics, 51(2), 258-266. Nature Publishing Group
the 23 and Me Research Team, Morris, J A, Kemp, J P, Youlten, S E, Laurent, L, Logan, J G, Chai, R C, Vulpescu, N A, Forgetta, V, Kleinman, A, Mohanty, S T, Sergio, C M, Quinn, J, Nguyen-Yamamoto, L, Luco, A L, Vijay, J, Simon, M M, Pramatarova, A, Medina-Gomez, C, Trajanoska, K, Ghirardello, E J, Butterfield, N C, Curry, K F, Leitch, V D, Sparkes, P C, Adoum, A T, Mannan, N S, Komla-Ebri, D S K, Pollard, A S, Dewhurst, H F, Hassall, T A D, Beltejar, M J G, Agee, M, Alipanahi, B, Auton, A, Bell, R K, Bryc, K, Elson, S L, Fontanillas, P, Furlotte, N A, McCreight, J C, Huber, K E, Litterman, N K, McIntyre, M H, Mountain, J L, Wilson, C H, Cooper, C, Tobias, J H, Gregson, C L, Adams, D J & Evans, D M 2019, ' An atlas of genetic influences on osteoporosis in humans and mice ', Nature Genetics, vol. 51, pp. 258–266 . https://doi.org/10.1038/s41588-018-0302-x
Nature genetics
the 23 and Me Research Team, Morris, J A, Kemp, J P, Youlten, S E, Laurent, L, Logan, J G, Chai, R C, Vulpescu, N A, Forgetta, V, Kleinman, A, Mohanty, S T, Sergio, C M, Quinn, J, Nguyen-Yamamoto, L, Luco, A L, Vijay, J, Simon, M M, Pramatarova, A, Medina-Gomez, C, Trajanoska, K, Ghirardello, E J, Butterfield, N C, Curry, K F, Leitch, V D, Sparkes, P C, Adoum, A T, Mannan, N S, Komla-Ebri, D S K, Pollard, A S, Dewhurst, H F, Hassall, T A D, Beltejar, M J G, Agee, M, Alipanahi, B, Auton, A, Bell, R K, Bryc, K, Elson, S L, Fontanillas, P, Furlotte, N A, McCreight, J C, Huber, K E, Litterman, N K, McIntyre, M H, Mountain, J L, Wilson, C H, Cooper, C, Tobias, J H, Gregson, C L, Adams, D J & Evans, D M 2019, ' An atlas of genetic influences on osteoporosis in humans and mice ', Nature Genetics, vol. 51, pp. 258–266 . https://doi.org/10.1038/s41588-018-0302-x
Nature genetics
Osteoporosis is a common debilitating chronic disease diagnosed primarily using bone mineral density (BMD). We undertook a comprehensive assessment of human genetic determinants of bone density in 426,824 individuals, identifying a total of 518 genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144c7600a65cf0f583134acbcbf5a1ba
http://hdl.handle.net/10044/1/66283
http://hdl.handle.net/10044/1/66283
Autor:
Esapa, CT, Piret, SE, Nesbit, MA, Thomas, GP, Coulton, LA, Gallagher, OM, Simon, MM, Kumar, S, Mallon, AM, Ballantuono, I, Brown, MA, Croucher, PI, Potter, PK, Brown, SDM, Cox, R, Thakker, RV
Kyphosis and scoliosis are common spinal disorders that occur as part of complex syndromes or as non-syndromic, idiopathic diseases. Familial and twin studies implicate genetic involvement, although the causative genes for idiopathic kyphoscoliosis r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::44141c5298adf0d649aae48830dc0e3b
https://ora.ox.ac.uk/objects/uuid:34a26d21-be0d-47e5-803e-8c98e4524c53
https://ora.ox.ac.uk/objects/uuid:34a26d21-be0d-47e5-803e-8c98e4524c53
Autor:
Kemp, JP, Morris, JA, Medina-Gomez, C, Forgetta, V, Warrington, NM, Youlten, SE, Zheng, J, Gregson, CL, Grundberg, E, Trajanoska, K, Logan, JC, Pollard, AS, Sparkes, PC, Ghirardello, EJ, Allen, R, Butterfield, NC, Komla-Ebri, D, Adoum, AT, Curry, KF, White, JK, Kussy, F, Greenlaw, KM, Xu, C, Harvey, NC, Cooper, C, Adams, DJ, Greenwood, CMT, Maurano, MT, Kaptoge, SK, Rivadeneira, F, Tobias, JH, Croucher, PI, Ackert-Bicknell, C, Bassett, JHD, Williams, GR, Richards, JB, Evans, DM
Osteoporosis is a common disease diagnosed primarily by measurement of bone mineral density (BMD). We undertook a genome-wide association study in 142,487 individuals from the UK Biobank to identify loci associated with BMD estimated by quantitative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b00a021d00674188a5f523e4f28f8eb
https://www.repository.cam.ac.uk/handle/1810/267772
https://www.repository.cam.ac.uk/handle/1810/267772
Autor:
Freudenthal, B, Logan, J, Sanger Institute Mouse Pipelines2, Croucher, PI, Williams, GR, Bassett, JHD
Publikováno v:
R46
R31
R31
The genetic determinants of osteoporosis remain poorly understood, and there is a large unmet need for new treatments in our ageing society. Thus, new approaches for gene discovery in skeletal disease are required to complement the current genome-wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::e46cbf5a38cc28d3c7ca208c21f5408e
http://hdl.handle.net/10044/1/39207
http://hdl.handle.net/10044/1/39207
Autor:
Holen, I, Wells, JM, Croucher, PI, Evans, CA, Lippitt, JM, Coleman, RE, Jagdev, SP, Hamdy, FC, Eaton, CL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d388a31eaf7782fa6860889a04ca8c23
https://ora.ox.ac.uk/objects/uuid:ccd7fbec-8277-4080-8b9e-fa4b3a63a8e9
https://ora.ox.ac.uk/objects/uuid:ccd7fbec-8277-4080-8b9e-fa4b3a63a8e9
Autor:
Croucher, PI, Shipman, CM, Perry, M, Lippitt, J, Asosingh, K, van Beek, EJR, Van Camp, B, Russell, RGG, Dunstan, C, Vanderkerken, K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9949ddd392c54cfa1429f0680d5c38b1
https://ora.ox.ac.uk/objects/uuid:c4c04d9f-e02a-4aa6-9df1-fcc52d8449c6
https://ora.ox.ac.uk/objects/uuid:c4c04d9f-e02a-4aa6-9df1-fcc52d8449c6