Potential Pitfalls of Using Fractional Anisotropy, Axial Diffusivity, and Radial Diffusivity as Biomarkers of Cerebral White Matter Microstructure

Autor: Chase R. Figley, Md Nasir Uddin, Kaihim Wong, Jennifer Kornelsen, Josep Puig, Teresa D. Figley

Publikováno v: Frontiers in Neuroscience, Vol 15 (2022)

Fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) are commonly used as MRI biomarkers of white matter microstructure in diffusion MRI studies of neurodevelopment, brain aging, and neurologic injury/disease. Some of the m

Externí odkaz: https://doaj.org/article/b38a20f6cbcf44c4aa60ce009446f506

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Diffusion-relaxation scattered MR signal representation in a multi-parametric sequence

Autor: Fabian Bogusz, Tomasz Pieciak, Maryam Afzali, Marco Pizzolato

Publikováno v: Magnetic resonance imaging. 91

This work focuses on obtaining a magnetic resonance imaging (MRI) signal representation that accounts for a longitudinal T-1 and transverse T-2* relaxations while at the same time integrating directional diffusion in the context of scattered multi-pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e77dd629903234d0d6e43a4acebb3c
https://pubmed.ncbi.nlm.nih.gov/35561868

Integrated and efficient diffusion-relaxometry using ZEBRA

Autor: Hutter, Jana, Slator, Paddy J, Christiaens, Daan, Teixeira, Rui Pedro AG, Roberts, Thomas, Jackson, Laurence, Price, Anthony N, Malik, Shaihan, Hajnal, Joseph V

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Hutter, J, Slator, P J, Christiaens, D, A. G. Teixeira, R P, Roberts, T, Jackson, L, Price, A N, Malik, S & Hajnal, J V 2018, ' Integrated and efficient diffusion-relaxometry using ZEBRA ', Scientific Reports, vol. 8, 15138 . https://doi.org/10.1038/s41598-018-33463-2

The emergence of multiparametric diffusion models combining diffusion and relaxometry measurements provides powerful new ways to explore tissue microstructure, with the potential to provide new insights into tissue structure and function. However, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4948d132131d2609cf2d0d621ef8b8b0
http://link.springer.com/article/10.1038/s41598-018-33463-2