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pro vyhledávání: '"Cronin, Leroy"'
Evolution is often understood through genetic mutations driving changes in an organism's fitness, but there is potential to extend this understanding beyond the genetic code. We propose that natural products - complex molecules central to Earth's bio
Externí odkaz:
http://arxiv.org/abs/2409.05993
Crystallisation is an important phenomenon which facilitates the purification as well as structural and bulk phase material characterisation using crystallographic methods. However, different conditions can lead to a vast set of different crystal str
Externí odkaz:
http://arxiv.org/abs/2409.05196
Autor:
Kahana, Amit, MacLeod, Alasdair, Mehr, Hessam, Sharma, Abhishek, Carrick, Emma, Jirasek, Michael, Walker, Sara, Cronin, Leroy
Here we demonstrate the first biochemistry-agnostic approach to map evolutionary relationships at the molecular scale, allowing the construction of phylogenetic models using mass spectrometry (MS) and Assembly Theory (AT) without elucidating molecula
Externí odkaz:
http://arxiv.org/abs/2408.09305
Autor:
Cronin, Leroy
This work establishes a rigorous proof for the universality of the chemputer as a chemical synthesis machine, capable of constructing any stable and isolable molecule through a finite, expressible process. This process is governed by three key parame
Externí odkaz:
http://arxiv.org/abs/2408.09171
Assembly theory (AT) quantifies selection using the assembly equation and identifies complex objects that occur in abundance based on two measurements, assembly index and copy number. The assembly index is determined by the minimal number of recursiv
Externí odkaz:
http://arxiv.org/abs/2406.12176
Assembly Theory (AT) was developed to help distinguish living from non-living systems. The theory is simple as it posits that the amount of selection or Assembly is a function of the number of complex objects where their complexity can be objectively
Externí odkaz:
http://arxiv.org/abs/2406.06826
Autor:
Cronin, Leroy
Assembly Theory (AT) is a theory that explains how to determine if a complex object is the product of evolution. Here we explain why attempts to compare AT to compression algorithms, ref 1, does not help identify if the object is the product of selec
Externí odkaz:
http://arxiv.org/abs/2403.12452
Autor:
Turyshev, Slava G., Garber, Darren, Friedman, Louis D., Hein, Andreas M., Barnes, Nathan, Batygin, Konstantin, Brin, G. David, Brown, Michael E., Cronin, Leroy, Davoyan, Artur, Dubill, Amber, Eubanks, T. Marshall, Gibson, Sarah, Hassler, Donald M., Izenberg, Noam R., Kervella, Pierre, Mauskopf, Philip D., Murphy, Neil, Nutter, Andrew, Porco, Carolyn, Riccobono, Dario, Schalkwyk, James, Stevenson, Kevin B., Sykes, Mark V., Sultana, Mahmooda, Toth, Viktor T., Velli, Marco, Worden, S. Pete
Publikováno v:
Planetary and Space Science 235 (2023) 105744
Recently, we witnessed how the synergy of small satellite technology and solar sailing propulsion enables new missions. Together, small satellites with lightweight instruments and solar sails offer affordable access to deep regions of the solar syste
Externí odkaz:
http://arxiv.org/abs/2303.14917
Autor:
Jirasek, Michael, Sharma, Abhishek, Bame, Jessica R., Mehr, S. Hessam M., Bell, Nicola, Marshall, Stuart M., Mathis, Cole, Macleod, Alasdair, Cooper, Geoffrey J. T., Swart, Marcel, Mollfulleda, Rosa, Cronin, Leroy
Determining the complexity of molecules has important applications from molecular design to understanding the history of the process that led to the formation of the molecule. Currently, it is not possible to experimentally determine, without full st
Externí odkaz:
http://arxiv.org/abs/2302.13753
Autor:
Sharma, Abhishek, Czégel, Dániel, Lachmann, Michael, Kempes, Christopher P., Walker, Sara I., Cronin, Leroy
Since the time of Darwin, scientists have struggled to reconcile the evolution of biological forms in a universe determined by fixed laws. These laws underpin the origin of life, evolution, human culture and technology, as set by the boundary conditi
Externí odkaz:
http://arxiv.org/abs/2206.02279