Zobrazeno 1 - 10
of 1 313
pro vyhledávání: '"Crome P"'
Autor:
Jessica A. Mathews, Dorota T. Borovsky, Kyle T. Reid, Julia M. Murphy, Sarah J. Colpitts, Abel Santos Carreira, Tommy Alfaro Moya, Douglas C. Chung, Igor Novitzky-Basso, Jonas Mattsson, Pamela S. Ohashi, Sarah Q. Crome
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111416- (2024)
Summary: Natural killer (NK) cell activity is influenced by cytokines and microenvironment factors, resulting in remarkably diverse functions, by contributing to inflammatory responses or serving as rheostats of adaptive immunity. Using single cell R
Externí odkaz:
https://doaj.org/article/2baf0f6025ed45cba21fb3b4c09ad125
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Innate lymphoid cells (ILCs) are a family of innate lymphocytes with important roles in immune response coordination and maintenance of tissue homeostasis. The ILC family includes group 1 (ILC1s), group 2 (ILC2s) and group 3 (ILC3s) ‘helper’ ILCs
Externí odkaz:
https://doaj.org/article/048f8e0d5a20456fbab3b5538022ff1e
Autor:
Caitriona M. McEvoy, Julia M. Murphy, Lin Zhang, Sergi Clotet-Freixas, Jessica A. Mathews, James An, Mehran Karimzadeh, Delaram Pouyabahar, Shenghui Su, Olga Zaslaver, Hannes Röst, Rangi Arambewela, Lewis Y. Liu, Sally Zhang, Keith A. Lawson, Antonio Finelli, Bo Wang, Sonya A. MacParland, Gary D. Bader, Ana Konvalinka, Sarah Q. Crome
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Knowledge of the transcriptional programs of human kidney cell populations at homeostasis is limited. Here, the authors show sex-based differences in gene expression of kidney parenchymal cells and examine the complexity of kidney-resident immune cel
Externí odkaz:
https://doaj.org/article/fe8594c88fdd42d5869600c16f1e2141
Akademický článek
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Autor:
Sarah J. Colpitts, Matthew A. Budd, Mahdis Monajemi, Kyle T. Reid, Julia M. Murphy, Sabine Ivison, C. Bruce Verchere, Megan K. Levings, Sarah Q. Crome
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Defining the immunological landscape of human tissue is an important area of research, but challenges include the impact of tissue disaggregation on cell phenotypes and the low abundance of immune cells in many tissues. Here, we describe methods to t
Externí odkaz:
https://doaj.org/article/a3403a527ce5473e87c809b9fafea3b5
Akademický článek
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Akademický článek
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Autor:
David R. W. MacDonald, David W. Neilly, Peter S. E. Davies, Christopher R. Crome, Bilal Jamal, Sarah L. Gill, Arpit C. Jariwala, Iain M. Stevenson, G. Patrick Ashcroft, SCORE authors
Publikováno v:
Bone & Joint Open, Vol 1, Iss 9, Pp 541-548 (2020)
Aims: The UK government declared a national lockdown on 23 March 2020 to reduce transmission of COVID-19. This study aims to identify the effect of lockdown on the rates, types, mechanisms, and mortality of musculoskeletal trauma across Scotland. Met
Externí odkaz:
https://doaj.org/article/7db4d1edd2b3425da841b1dca2cad4e3
Autor:
Elissa G. Currie, Bryan Coburn, Elisa A. Porfilio, Ping Lam, Olga L. Rojas, Jan Novak, Stuart Yang, Raad B. Chowdhury, Lesley A. Ward, Pauline W. Wang, Khashayar Khaleghi, James An, Sarah Q. Crome, Michelle A. Hladunewich, Sean J. Barbour, Daniel C. Cattran, Rulan S. Parekh, Christoph Licht, Rohan John, Rupert Kaul, Kenneth Croitoru, Scott D. Gray-Owen, David S. Guttman, Jennifer L. Gommerman, Heather N. Reich
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
IgA nephropathy (IgAN) is a leading cause of kidney failure, yet little is known about the immunopathogenesis of this disease. IgAN is characterized by deposition of IgA in the kidney glomeruli, but the source and stimulus for IgA production are not
Externí odkaz:
https://doaj.org/article/594e642df71840fcba72985a2ef82850
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tissue-resident immune cells reside in distinct niches across organs, where they contribute to tissue homeostasis and rapidly respond to perturbations in the local microenvironment. Innate lymphoid cells (ILCs) are a family of innate immune cells tha
Externí odkaz:
https://doaj.org/article/07c1489532fa41c8a66280c07195f44b