Výsledky vyhledávání - "Crocifissa Lo Cunsolo"

1q23.1 homozygous deletion and downregulation of Fc receptor-like family genes confer poor prognosis in chronic lymphocytic leukemia

Autor: Clelia Tiziana Storlazzi, Giulia Daniele, Antonella Turchiano, Crocifissa Lo Cunsolo, María Hernández-Sánchez, Patrizia Leone, P. Iuzzolino, Angelo Lonoce, Carla Minoia, Orazio Palumbo, Massimo Carella, Jesús María Hernández-Rivas, Alberto L'Abbate

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

The identification of chromosome 1 translocations and deletions is a rare and poorly investigated event in chronic lymphocytic leukemia (CLL). Nevertheless, the identification of novel additional molecular alterations is of great interest, opening to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c2e9e12047cbba144e411752e6f4c2
http://hdl.handle.net/10261/202827

Zobrazit plný text záznamu

A rare but recurrent t(8;13)(q24;q14) translocation in B-cell chronic lymphocytic leukaemia causingMYCup-regulation and concomitant loss ofPVT1,miR-15/16andDLEU7

Autor: Santina Venuto, Clelia Tiziana Storlazzi, Gemma Macchia, Angelo Lonoce, Massimo Carella, P. Iuzzolino, María Hernández-Sánchez, Ettore Macrì, Jesús M. Hernández-Rivas, Orazio Palumbo, Crocifissa Lo Cunsolo

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

B-cell chronic lymphocytic leukaemia (B-CLL) is the most common haematological malignancy in Western countries. Trisomy 12 (12%), and deletions of 13q14 (50%), 11q23 (18%) and 17p13 (7%) are the most frequent chromosomal aberrations (Palamarchuk et a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3e680dcde358f0c8009402f8d10361
https://doi.org/10.1111/bjh.13482

Zobrazit plný text záznamu

FOXP1 and TP63 involvement in the progression of myelodysplastic syndrome with 5q- and additional cytogenetic abnormalities

Autor: Claudio Agostinelli, Alberto L'Abbate, Michelina Coco, Lucia Anna Muscarella, Crocifissa Lo Cunsolo, Clelia Tiziana Storlazzi, Nicoletta Testoni, Carla Minoia, Cristina Mecucci, Simona Salati, Ettore Macrì, Enrico Tagliafico, Attilio Guarini, Giacoma De Tullio, P. Iuzzolino, Claudio Doglioni

Publikováno v: BMC Cancer

BACKGROUND: The progression of low-risk del(5q) myelodysplastic syndrome to acute myeloid leukemia is increased when associated with mutations of TP53, or with additional chromosomal abnormalities. However, to date the prognostic impact and molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36306fd8ae7943eca88722fff387aa2e
https://hdl.handle.net/11380/1060248

Zobrazit plný text záznamu

t(15;21) translocations leading to the concurrent downregulation of RUNX1 and its transcription factor partner genes SIN3A and TCF12 in myeloid disorders

Autor: Clelia Tiziana Storlazzi, D. Mühlematter, Doron Tolomeo, Massimo Carella, Achilles Van Hoof, Francesca De Astis, Tommaso Mazza, Peter Vandenberghe, Jacqueline Schoumans, Alberto L'Abbate, Angelo Lonoce, Crocifissa Lo Cunsolo, Orazio Palumbo

Publikováno v: Molecular Cancer, vol. 14, no. 1, pp. 211
Molecular Cancer

Through a combined approach integrating RNA-Seq, SNP-array, FISH and PCR techniques, we identified two novel t(15;21) translocations leading to the inactivation of RUNX1 and its partners SIN3A and TCF12. One is a complex t(15;21)(q24;q22), with both

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff7db2a00c7cb9e45e0ec3501b9e96e
http://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-015-0484-0

Zobrazit plný text záznamu

Characterization of t(6;11)(p21;q12) in a renal-cell carcinoma of an adult patient

Autor: Claudio Doglioni, Ettore Macrì, Crocifissa Lo Cunsolo, Lorenza Pecciarini, Guido Martignoni, Elena Dal Cin, M. Giulia Cangi

Publikováno v: Genes, Chromosomes and Cancer. 46:419-426

Renal-cell carcinoma (RCC) constitutes a heterogeneous group of tumors with specific chromosome aberrations. Recently, a new small group of RCC, occurring in children and young adults, has been described as characterized by t(6;11)(p21;q12). It has b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2042b24ad8d7d340129a9d55040970f2
https://doi.org/10.1002/gcc.20422

Zobrazit plný text záznamu

Stage-independent expression and genetic analysis oftp73 in neuroblastoma

Autor: Gian Paolo Tonini, Claudio Gambini, Massimo Romani, Ida Casciano, Paola Scaruffi, Crocifissa Lo Cunsolo, Bruno De Bernardi, Luca Boni, Andrea Cavazzana, Katia Mazzocco

Publikováno v: International Journal of Cancer. 84:365-369

The tp73 gene, a tp53 homologue, has been sub-regionally mapped at 1p36.3, a chromosomal region frequently deleted in neuroblastoma. Due to its chromosomal localization and to the mono-allelic expression observed in some neuroblastoma cell lines, it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45bf9bebb2bc890b752ff2480c437b26
https://doi.org/10.1002/(sici)1097-0215(19990820)84:4<365::aid-ijc6>3.0.co

Zobrazit plný text záznamu

Neuroblastoma in Two Siblings Supports the Role of 1p36 Deletion in Tumor Development

Autor: Lucia Giordani, Katia Mazzocco, Crocifissa Lo Cunsolo, Luisa M. Massimo, Bruno De Bernardi, Massimo Conte, Achille Iolascon, Roberto Cusano, Andrea Cavazzana, Gian Paolo Tonini, Paolo Strigini

Publikováno v: Cancer Genetics and Cytogenetics. 109:126-130

Familial neuroblastoma occurs rarely. We studied a family with three children; one of them has a disseminated (stage 4) and another has a localized (stage 2) neuroblastoma. We observed subtelomeric locus D1Z2 (1p36) deletion in both tumors by using d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e4ea106b72cc5b7ccf5fefe39aafd5
https://doi.org/10.1016/s0165-4608(98)00154-x

Zobrazit plný text záznamu

Homozygous inactivation of NF1 gene in a patient with familial NF1 and disseminated neuroblastoma

Autor: Katia Mazzocco, Gian Paolo Tonini, Bruno De Bernardi, Crocifissa Lo Cunsolo, Raffaella Defferrari, Paola Origone

Publikováno v: American journal of medical genetics. Part A. (4)

Neurofibromatosis type 1 (NF1) patients are susceptible to tumor development. In the present study we describe a child with NF1 and disseminated neuroblastoma whose death resulted from disease progression. The mother had cafe-au-lait spots suggesting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2fd1dfa81a90c60ac65ac0bf2fb47d3
https://pubmed.ncbi.nlm.nih.gov/12687660

Zobrazit plný text záznamu

Transformation of normal human cells in the absence of telomerase activation

Autor: Claudio Doglioni, Gregory J. Hannon, Sara Piccinin, Roberta Maestro, Yvette R. Seger, Marta García-Cao, Crocifissa Lo Cunsolo, Maria A. Blasco

Our knowledge of the transformation process has emerged largely from studies of primary rodent cells and animal models. However, numerous attempts to transform human cells using oncogene combinations that are effective in rodents have proven unsucces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4fc9024047d3a89e8a49770b518c18b

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání