Circulating Micrornas Predict Survival of Patients with Tumors of Glial Origin

Autor: Drusco A, P. Fadda, Nigita G, Fassan M, Bottoni A, Gardiman MP, D. Sacchi, Calore F, Carosi M, Antenucci A, B. Casini, Kelani H, Pescarmona E, Di Leva G, Zanesi N, Berger MS, Croce CM

Publikováno v: EBioMedicine, Vol 30, Iss , Pp 105-112 (2018)

The World Health Organization has recently introduced molecular prognostic-diagnostic biomarkers in the classification of Central Nervous System (CNS) tumors. In order to characterize subclasses of tumors that cannot find a precise location in the cu

Externí odkaz: https://doaj.org/article/1d94bf293ca3445886ce9ed8b46c5acc

Akt regulates drugs induced cell death through the anti-apoptotic protein Bcl-w

Autor: Garofalo M, Quintavalle C, Zanca C, de Rienzo A., Romano G, Acunzo M, Puca L, Incoronato M, Croce CM, CONDORELLI, GEROLAMA

Akt is a serine threonine kinase with a major role in transducing survival signals and regulating proteins involved in apoptosis. To find new interactors of Akt involved in cell survival, we performed a two-hybrid screening in yeast using human full-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::cc54557095fcd5c54414c16718696dbd
http://hdl.handle.net/11588/343302

Anti-miR-135b in colon cancer treatment: Results from a preclinical study

Autor: Valeri, N, Braconi, C, Gasparini, P, Grivennikow, S, Hart, Jr, Paone, A, Lovat, F, Fabbri, M, Gafa', R, Nuovo, G, Lanza, G, Frankel, W, Vogt, Pk, Groden, J, Karin, M, Croce, Cm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3709::7a20c4ee5364dac9dec4bd47cac2ca89
http://hdl.handle.net/11392/2389256

EGFR and MET induce tumorigenesis and gefitinib resistance in lung cancers by controlling microRNA expression

Autor: Garofalo M1, Romano G, Di Leva G, Nuovo G, Jeon YJ, Ngankeu A, Sun J, Lovat F, Alder H, Condorelli G, Engelman JA, Ono M, Rho JK, Cascione L, Volinia S, Nephew KP, Croce CM.

Publikováno v: Nature medicine
(2011).
info:cnr-pdr/source/autori:Garofalo M1, Romano G, Di Leva G, Nuovo G, Jeon YJ, Ngankeu A, Sun J, Lovat F, Alder H, Condorelli G, Engelman JA, Ono M, Rho JK, Cascione L, Volinia S, Nephew KP, Croce CM./titolo:EGFR and MET induce tumorigenesis and gefitinib resistance in lung cancers by controlling microRNA expression/doi:/rivista:Nature medicine (Print)/anno:2011/pagina_da:/pagina_a:/intervallo_pagine:/volume

The involvement of the MET oncogene in de novo and acquired resistance of non-small cell lung cancers (NSCLCs) to tyrosine kinase inhibitors (TKIs) has previously been reported, but the precise mechanism by which MET overexpression contributes to TKI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::96094bcd487c8711cb718cb788079e81
http://www.cnr.it/prodotto/i/340724

Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic mice

Autor: Costinean, S, Sandhu, SK, Pedersen, IM, Tili, E, Trotta, R, Perrotti, D, Ciarlariello, D, Neviani, P, Harb, J, Kauffman, LR, Shidham, A, Croce, CM

Publikováno v: Costinean, S; Sandhu, SK; Pedersen, IM; Tili, E; Trotta, R; Perrotti, D; et al.(2009). Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic mice.. Blood, 114(7), 1374-1382. doi: 10.1182/blood-2009-05-220814. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6rg1h7k5

We showed that Emicro-MiR-155 transgenic mice develop acute lymphoblastic leukemia/high-grade lymphoma. Most of these leukemias start at approximately 9 months irrespective of the mouse strain. They are preceded by a polyclonal pre-B-cell proliferati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::7808b22d4515d72f1977306b5b24b43b
http://www.escholarship.org/uc/item/6rg1h7k5