Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Cristoforo Scavone"'
Autor:
Davi Azevedo Ferreira, Anna Beatriz Araujo Medeiros, Mariana Mendonça Soares, Éssia de Almeida Lima, Gabriela Carolina Santos Lima de Oliveira, Mateus Bernardo da Silva Leite, Matheus Vieira Machado, José Augusto Ferreira Perez Villar, Leandro Augusto Barbosa, Cristoforo Scavone, Marcelo Tigre Moura, Sandra Rodrigues-Mascarenhas
Publikováno v:
Cells, Vol 13, Iss 18, p 1568 (2024)
Cardiotonic steroids are known to bind to Na+/K+-ATPase and regulate several biological processes, including the immune response. The synthetic cardiotonic steroid γ-Benzylidene Digoxin 8 (BD-8) is emerging as a promising immunomodulatory molecule,
Externí odkaz:
https://doaj.org/article/a7ce4a90f6704e5d80aadee548dacc03
Autor:
Ana Maria Orellana, Caio Henrique Mazucanti, Leticia Pavan dos Anjos, Larissa de Sá Lima, Elisa Mitiko Kawamoto, Cristoforo Scavone
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Klotho is an antiaging protein, and its levels decline with age and chronic stress. The exogenous administration of Klotho can enhance cognitive performance in mice and negatively modulate the Insulin/IGF1/PI3K/AKT pathway in terms of metabo
Externí odkaz:
https://doaj.org/article/5740c89bab104784b8902ee6be6d8599
Autor:
Alexandre Chagas Santana, Wellington Andraus, Dan Zimelewicz Oberman, Nícollas Nunes Rabelo, Filipe Miranda Oliveira Silva, Humberto Dellê, Rafael Pepineli, Edvaldo Leal de Moraes, Cristoforo Scavone, Larissa de Sá Lima, Sabrina Degaspari, Sérgio Brasil, Davi Jorge Fontoura Solla, Liliane Moreira Ruiz, Karina Andrighetti de Oliveira-Braga, Natalia Aparecida Nepomuceno, Paulo Manuel Pêgo-Fernandes, Stefan Gunther Tullius, Eberval Gadelha Figueiredo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Liver transplantation has come a long way and is now regarded as the gold standard treatment for end-stage liver failure. The great majority of livers utilized in transplantation come from brain-dead donors. A broad inflammatory response cha
Externí odkaz:
https://doaj.org/article/75148395e7e1446d9d765d116d6e8d60
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/6dc7f7e483684abf82c5da556819f134
Autor:
Martina Ribeiro, Julia Nachbar, Maria Oliveira, Amanda Siena, Isabela Melhado, Victoria Alves, Thiago Lima, Henrique Moriya, Larissa De Sá Lima, Ana Orellana, Ricardo Oliveira-Filho, Wothan Tavares-De-Lima, Cristoforo Scavone
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S288- (2023)
Externí odkaz:
https://doaj.org/article/5ffee398a1a449d59a28c7569e4ec565
Autor:
Amanda Siena Dos Santos, Luiz Felipe Souza E Silva, Vitória Cristina Araújo, Martina Ribeiro, Pedro Ismael Da Silva Júnior, Tatiana Rosado Rosenstock, Cristoforo Scavone
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S140- (2023)
Externí odkaz:
https://doaj.org/article/7befbbf9fd8a4816ae32bb2fe17fb9bb
Autor:
Vinicius Wanatable Nakao, Caio Henrique Yokowama Mazucanti, Larissa de Sá Lima, Paloma Segura de Mello, Natacha Medeiros de Souza Port’s, Paula Fernanda Kinoshita, Jacqueline Alves Leite, Elisa Mitiko Kawamoto, Cristoforo Scavone
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The α-Klotho is an anti-aging protein that, when overexpressed, extends the life span in humans and mice. It has an anti-inflammatory and protective action on renal cells by inhibiting NF-κB activation and production of inflammatory cytoki
Externí odkaz:
https://doaj.org/article/68d440f26bb4423290f31765cc6d931a
Autor:
Marina Minto Cararo-Lopes, Débora Guerini Souza, Marcelo Ganzella, Gisele Hansel, Vanessa Kazlauckas, Paloma Segura De Mello, Larissa De Sá Lima, Elisa Mitiko Kawamoto, Luis Valmor Portela, Diogo Onofre Souza, Cristoforo Scavone, Ana Elisa Böhmer
Publikováno v:
Journal of Affective Disorders Reports, Vol 10, Iss , Pp 100394- (2022)
Background: Chronic immunosuppressive treatment with cyclosporine A (CsA) leads to multiple side effects, including some that occur in the central nervous system (CNS). This study aims to investigate the impact of long-term CsA treatment on anxiety b
Externí odkaz:
https://doaj.org/article/f99023825e4d4fe69ee5ec7611242149
Autor:
Alexandre Chagas Santana, Wellington Andraus, Filipe Miranda Oliveira Silva, Humberto Dellê, Rafael Pepineli, Edvaldo Leal de Moraes, Cristoforo Scavone, Larissa de Sá Lima, Sabrina Degaspari, Sergio Brasil, Davi Jorge Fontoura Solla, Liliane Moreira Ruiz, Karina Andrighetti de Oliveira-Braga, Natalia Aparecida Nepomuceno, Paulo Manuel Pêgo-Fernandes, Stefan Gunther Tullius, Eberval Gadelha Figueiredo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Brain death is characterized by a generalized inflammatory response that results in multiorgan damage. This process is mainly mediated through cytokines, which amplify graft immunogenicity. We investigated the immunological response in a bra
Externí odkaz:
https://doaj.org/article/c377023aeb3c49e0bf911f268d1c356c
Autor:
Jacqueline Alves Leite, Elisa Pôças, Gisele Silva Maia, Leandro Barbosa, Luis Eduardo M. Quintas, Elisa Mitiko Kawamoto, Maria Luiza Correia da Silva, Cristoforo Scavone, Luciana E. Drumond de Carvalho
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The Na+/K+-ATPase is an integral membrane ion pump, essential to maintaining osmotic balance in cells in the presence of cardiotonic steroids; more specifically, ouabain can be an endogenous modulator of the Na+/K+-ATPase. Here, we conducted a system
Externí odkaz:
https://doaj.org/article/7fba19639a3945f4b1658006ac628cea