Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Cristobal L. Miranda"'
Autor:
Payel Kundu, Ines L. Paraiso, Jaewoo Choi, Cristobal L. Miranda, Chrissa Kioussi, Claudia S. Maier, Gerd Bobe, Jan F. Stevens, Jacob Raber
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 11 (2022)
Externí odkaz:
https://doaj.org/article/dea6d5ca8f2d46fc87f45c94e18d8c3f
Autor:
Payel Kundu, Sarah Holden, Ines L. Paraiso, Reetesh Sudhakar, Chloe McQuesten, Jaewoo Choi, Cristobal L. Miranda, Claudia S. Maier, Gerd Bobe, Jan F. Stevens, Jacob Raber
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Consumption of a high fat diet (HFD) is linked to metabolic syndrome and cognitive impairments. This is exacerbated in age-related cognitive decline (ACD) and in individuals with a genetic risk for Alzheimer’s disease (AD). Apolipoprotein E (apoE)
Externí odkaz:
https://doaj.org/article/6da310e68f4e4e4aad956e7b1ab81a6f
Autor:
Kevin S. Brown, Paige Jamieson, Wenbin Wu, Ashish Vaswani, Armando Alcazar Magana, Jaewoo Choi, Luce M. Mattio, Paul Ha-Yeon Cheong, Dylan Nelson, Patrick N. Reardon, Cristobal L. Miranda, Claudia S. Maier, Jan F. Stevens
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1400 (2022)
The slow pace of discovery of bioactive natural products can be attributed to the difficulty in rapidly identifying them in complex mixtures such as plant extracts. To overcome these hurdles, we explored the utility of two machine learning techniques
Externí odkaz:
https://doaj.org/article/9399bce4f40b420c9edc91e5af41ea89
Autor:
Isabelle E. Logan, Gerd Bobe, Cristobal L. Miranda, Stephany Vasquez-Perez, Jaewoo Choi, Malcolm B. Lowry, Thomas J. Sharpton, Andrey Morgun, Claudia S. Maier, Jan F. Stevens, Natalia Shulzhenko, Adrian F. Gombart
Publikováno v:
Microorganisms, Vol 8, Iss 4, p 520 (2020)
A calorie-dense diet is a well-established risk factor for obesity and metabolic syndrome (MetS), whereas the role of the intestinal microbiota (IMB) in the development of diet-induced obesity (DIO) is not completely understood. To test the hypothesi
Externí odkaz:
https://doaj.org/article/178af5bf71a84aa290ad54d28a43a9f7
Autor:
Armando Alcazar Magana, Ralph L. Reed, Rony Koluda, Cristobal L. Miranda, Claudia S. Maier, Jan F. Stevens
Publikováno v:
Antioxidants, Vol 9, Iss 3, p 217 (2020)
Vitamin C (L-ascorbic acid, AA) is an essential cellular antioxidant and cofactor for several α-ketoglutarate-dependent dioxygenases. As an antioxidant, AA interacts with vitamin E to control oxidative stress. While several reports suggest an intera
Externí odkaz:
https://doaj.org/article/a4ab73c686ec4495808396cae7043401
Autor:
Elizabeth Rose Axton, Eleonso Cristobal, Jaewoo Choi, Cristobal L. Miranda, Jan Frederik Stevens
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Glyceryl trinitrate (GTN) has found widespread use for the treatment of angina pectoris, a pathological condition manifested by chest pain resulting from insufficient blood supply to the heart. Metabolic conversion of GTN, a nitric oxide (NO) pro-dru
Externí odkaz:
https://doaj.org/article/ea651f4c3b2549ba86af780e97832e42
Autor:
Evan L. Carpenter, Mai N. Le, Cristobal L. Miranda, Ralph L. Reed, Jan F. Stevens, Arup K. Indra, Gitali Ganguli-Indra
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Exposure to ultraviolet B (UVB) irradiation of the skin leads to numerous dermatological concerns including skin cancer and accelerated aging. Natural product glucosinolate derivatives, like sulforaphane, have been shown to exhibit chemopreventive an
Externí odkaz:
https://doaj.org/article/1a1002b1e5844daab387547eb09a8eac
Autor:
Claudia S. Maier, Liping Yang, Zifeng Song, Shay Bracha, Milan Milovancev, Siva Kumar Kolluri, Cristobal L. Miranda, Martin C. Pearce, Yuan Jiang, Cheri P. Goodall
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Osteosarcoma (OS) is the most common bone cancer in children and young adults. Solid tumors are characterized by intratumoral hypoxia, and hypoxic cells are associated with the transformation to aggressive phenotype and metastasis. The proteome neede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64038f2d0b74e208c8331d3d7e2b18de
http://link.springer.com/article/10.1038/s41598-019-56878-x
http://link.springer.com/article/10.1038/s41598-019-56878-x
Autor:
Yang Zhang, Claudia S. Maier, Christiane V. Löhr, Donald B. Jump, Carmen P. Wong, Cristobal L. Miranda, Jan F. Stevens, Gerd Bobe, Malcolm B. Lowry, Matthew M. Robinson, Adrian F. Gombart, Victor L. Hsu, Thomas J. Sharpton
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
We previously reported xanthohumol (XN), and its synthetic derivative tetrahydro-XN (TXN), attenuates high-fat diet (HFD)-induced obesity and metabolic syndrome in C57Bl/6J mice. The objective of the current study was to determine the effect of XN an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4632291738ce2d21a7f5039f27b8c0
http://europepmc.org/articles/PMC8205491
http://europepmc.org/articles/PMC8205491
Publikováno v:
Natural Product Communications. 17:1934578X2211094
Phytochemicals from the genus, Fagonia, have been attracting increasing attention due to their potential beneficial effects on human health. Fagonia species contain various types of phytochemicals such as flavonoids, alkaloids, saponins, terpenoids,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04f7e4200de78746fb2a79ea32af0519
https://doi.org/10.1177/1934578x221109426
https://doi.org/10.1177/1934578x221109426