Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Cristobal Dos Remedios"'
Autor:
Ramin Garmany, J. Martijn Bos, Surendra Dasari, Kenneth L. Johnson, David J. Tester, John R. Giudicessi, Cristobal dos Remedios, Joseph J. Maleszewski, Steve R. Ommen, Joseph A. Dearani, Michael J. Ackerman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Hypertrophic cardiomyopathy (HCM) is a genetically heterogenous condition with about half of cases remaining genetically elusive or non-genetic in origin. HCM patients with a positive genetic test (HCMSarc) present earlier and with more seve
Externí odkaz:
https://doaj.org/article/a99b2ac7a21c4d5cb14ce68d4ce59585
Autor:
Kristina Sonnenschein, Jan Fiedler, David de Gonzalo-Calvo, Ke Xiao, Angelika Pfanne, Annette Just, Carolin Zwadlo, Samira Soltani, Udo Bavendiek, Theresia Kraft, Cristobal Dos Remedios, Serghei Cebotari, Johann Bauersachs, Thomas Thum
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Hypertrophic cardiomyopathy (HCM) is one of the most common hereditary heart diseases and can be classified into an obstructive (HOCM) and non-obstructive (HNCM) form. Major characteristics for HCM are the hypertrophy of cardiomyocytes and d
Externí odkaz:
https://doaj.org/article/512e2ec0033c4485af4d7813594d8685
Autor:
Emilie Auxerre-Plantié, Tanja Nielsen, Marcel Grunert, Olga Olejniczak, Andreas Perrot, Cemil Özcelik, Dennis Harries, Faramarz Matinmehr, Cristobal Dos Remedios, Christian Mühlfeld, Theresia Kraft, Rolf Bodmer, Georg Vogler, Silke R. Sperling
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 12 (2020)
The causal genetic underpinnings of congenital heart diseases, which are often complex and multigenic, are still far from understood. Moreover, there are also predominantly monogenic heart defects, such as cardiomyopathies, with known disease genes f
Externí odkaz:
https://doaj.org/article/3ad5653fc6794cb9940a877a8adecd22
Autor:
Matthias Heinig, Michiel E. Adriaens, Sebastian Schafer, Hanneke W. M. van Deutekom, Elisabeth M. Lodder, James S. Ware, Valentin Schneider, Leanne E. Felkin, Esther E. Creemers, Benjamin Meder, Hugo A. Katus, Frank Rühle, Monika Stoll, François Cambien, Eric Villard, Philippe Charron, Andras Varro, Nanette H. Bishopric, Alfred L. George, Cristobal dos Remedios, Aida Moreno-Moral, Francesco Pesce, Anja Bauerfeind, Franz Rüschendorf, Carola Rintisch, Enrico Petretto, Paul J. Barton, Stuart A. Cook, Yigal M. Pinto, Connie R. Bezzina, Norbert Hubner
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-21 (2017)
Abstract Background Genetic variation is an important determinant of RNA transcription and splicing, which in turn contributes to variation in human traits, including cardiovascular diseases. Results Here we report the first in-depth survey of heart
Externí odkaz:
https://doaj.org/article/8e7bacbcd5ca43fa9bd815bc4899b453
Autor:
Steven Marston, Cecile Montgiraud, Alex B Munster, O'Neal Copeland, Onjee Choi, Cristobal Dos Remedios, Andrew E Messer, Elisabeth Ehler, Ralph Knöll
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138568 (2015)
BackgroundStudies of the functional consequences of DCM-causing mutations have been limited to a few cases where patients with known mutations had heart transplants. To increase the number of potential tissue samples for direct investigation we perfo
Externí odkaz:
https://doaj.org/article/21b7a55348dd474487eea475a9a01194
Autor:
Tamara T Koopmann, Michiel E Adriaens, Perry D Moerland, Roos F Marsman, Margriet L Westerveld, Sean Lal, Taifang Zhang, Christine Q Simmons, Istvan Baczko, Cristobal dos Remedios, Nanette H Bishopric, Andras Varro, Alfred L George, Elisabeth M Lodder, Connie R Bezzina
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97380 (2014)
In recent years genome-wide association studies (GWAS) have uncovered numerous chromosomal loci associated with various electrocardiographic traits and cardiac arrhythmia predisposition. A considerable fraction of these loci lie within inter-genic re
Externí odkaz:
https://doaj.org/article/326b3c5dcecf434d8c8e44ecb7c564f8
Autor:
Cristobal dos Remedios
Publikováno v:
Biophysical reviews. 14(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4ebf5892ef48ed0869bfb84448d73c
https://pubmed.ncbi.nlm.nih.gov/36345279
https://pubmed.ncbi.nlm.nih.gov/36345279
Autor:
Amy Li, K. Campbell, S. Lal, Y. Ge, A. Keogh, P. S. Macdonald, P. Lau, John Lai, W. A. Linke, J. Van der Velden, A. Field, B. Martinac, M. Grosser, Cristobal dos Remedios
Publikováno v:
Li, A, Campbell, K, Lal, S, Ge, Y, Keogh, A, Macdonald, P S, Lau, P, Lai, J, Linke, W A, van der Velden, J, Field, A, Martinac, B, Grosser, M & dos Remedios, C 2022, ' Peripartum cardiomyopathy : a global effort to find the cause and cure for the rare and little understood disease ', Biophysical Reviews, vol. 14, no. 1, pp. 369-379 . https://doi.org/10.1007/s12551-022-00930-0
In this review, we present our current understanding of peripartum cardiomyopathy (PPCM) based on reports of the incidence, diagnosis and current treatment options. We summarise opinions on whether PPCM is triggered by vascular and/or hormonal causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af94b5d0b6a1bcce56d9c9c48ba737b8
https://doi.org/10.1007/s12551-022-00930-0
https://doi.org/10.1007/s12551-022-00930-0
Autor:
Ramin Garmany, Johan M. Bos, Surendra Dasari, David Tester, Cristobal dos Remedios, Joseph Maleszewski, Steve Ommen, Joseph A. Dearani, John R. Giudicessi, Michael J. Ackerman
Publikováno v:
Heart Rhythm. 20:S262
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df3502c4b1c4defecf4ce22c8a0f47e2
https://doi.org/10.1016/j.hrthm.2023.03.714
https://doi.org/10.1016/j.hrthm.2023.03.714
Autor:
Zaher Elbeck, Mohammad Bakhtiar Hossain, Humam Siga, Nikolay Oskolkov, Fredrik Karlsson, Julia Lindgren, Anna Walentinsson, Cristobal Dos Remedios, Dominique Koppenhöfer, Rebecca Jarvis, Roland Bürli, Tanguy Jamier, Elske Franssen, Mike Firth, Andrea Degasperi, Claus Bendtsen, Jan Dudek, Michael Kohlhaas, Alexander G. Nickel, Lars H. Lund, Christoph Maack, Ákos Végvári, Christer Betsholtz
Excessive production of reactive oxygen species (ROS) is characteristic of numerous diseases, but most studies in this area have not considered the impact of endogenous antioxidative defenses. Here, utilizing multi-omics, we demonstrate that in cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e153b3159d4e22122f6aa6818cb7d0d3
https://doi.org/10.1101/2022.03.26.485908
https://doi.org/10.1101/2022.03.26.485908
