Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Cristinel, Sandu"'
Autor:
Sophia Liu, Yuetian Yan, Cody M. Secor, Zachary R. Oberholtzer, Donna J. Skow, Mushhood Sheikh, Youmi Moon, Yue Fu, Cristinel Sandu, Shunhai Wang, Ning Li, Jennifer B. Nguyen, Michael P. Rosconi, Erica A. Pyles
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTCo-formulation of multiple drug products is an efficient and convenient approach to simultaneously deliver multiple biotherapeutics with the potentially added benefit of a synergistic therapeutic effect. However, co-formulation also increases
Externí odkaz:
https://doaj.org/article/1494bc863c804d3eb9523d2ed2f12fcb
Autor:
Popescu, Cristinel – Sandu
Publikováno v:
Management & Marketing - Craiova. (1):119-122
Externí odkaz:
https://www.ceeol.com/search/article-detail?id=180733
Autor:
Cristinel – Sandu POPESCU
Publikováno v:
Management & Marketing, Iss 1, Pp 119-122 (2006)
In this paper we develop the concept of distribution on automobiledistribution. We consider the distribution as a neglected and fragmentedsector of the automobile industries. We also analyzed the distribution fromGreat Britanie, SUA, Japan, France an
Externí odkaz:
https://doaj.org/article/e65d819d71054f77acd81f5c04481b0b
Autor:
Hongbao Ma, Victoria Antonetti, Jason Mighty, Stephen Redenti, Linda Saxe Einbond, Cristinel Sandu, Margaret Ford, Hsan-au Wu
Publikováno v:
Fitoterapia. 109:146-154
Background The cardiac glycoside digitoxin preferentially inhibits the growth of breast cancer cells and targets the Erk pathway. Digitoxin alters the expression of genes that mediate calcium metabolism and IAP genes. Purpose Since the optimal treatm
Autor:
Nagaranjan Chandramouli, Hermann Steller, Alfred L. Goldberg, J.F. Glickman, Nikolay V. Kukushkin, Henrik Molina, Cristinel Sandu, Chueh-Ling Kuo
Publikováno v:
Journal of Cellular and Molecular Medicine
Here, we report a novel mechanism of proteasome inhibition mediated by Thiostrepton (Thsp), which interacts covalently with Rpt subunits of the 19S proteasome and proteasome substrates. We identified Thsp in a cell-based high-throughput screen using
Autor:
Gaku Morisawa, Yu Wei, Paul E. Carrington, Yufeng Wei, Evridipis Gavathiotis, Ted Huang, Milton H. Werner, Justine M. Hill, Cristinel Sandu
Publikováno v:
Molecular Cell. 22:599-610
The structure of FADD has been solved in solution, revealing that the death effector domain (DED) and death domain (DD) are aligned with one another in an orthogonal, tail-to-tail fashion. Mutagenesis of FADD and functional reconstitution with its bi
Autor:
Craig M. Walsh, Cristinel Sandu, Milton H. Werner, T Kim, Adrian F. Arechiga, Justine M. Hill, I Wegorzewska, Gaku Morisawa, Ted Huang
Publikováno v:
Cell Death & Differentiation. 13:2052-2061
Receptor-mediated programmed cell death proceeds through an activated receptor to which the death adaptor FADD and the initiator procaspases 8 and/or 10 are recruited following receptor stimulation. The adaptor FADD is responsible for both receptor b
Publikováno v:
Applied and Environmental Microbiology. 71:8920-8924
The first inducible Arthrobacter overexpression system, based on the promoter/operator and the repressor of the 6- d -hydroxynicotine oxidase gene of Arthrobacter nicotinovorans , is described here. Nicotine-dependent overproduction and affinity puri
Autor:
Cristinel Sandu, Roderich Brandsch
Publikováno v:
Archives of Microbiology. 178:465-470
The function of the MoeA protein in the biosynthesis of the molybdenum cofactor (MoCo) was analyzed in vitro, using purified His(6)-MoeA from Escherichia coli, molybdopterin (MPT) isolated from buttermilk xanthine oxidase and molybdate. The formation
Publikováno v:
Advances in experimental medicine and biology. 806
Thiostrepton is a natural antibiotic produced by bacteria of Streptomyces genus. We identified Thiostrepton as a strong hit in a cell-based small molecule screen for DIAP1 stability modulators. It was shown previously that Thiostrepton induces upregu