Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Cristine L Heaps"'
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191418 (2018)
Estrogen exerts protective effects against cardiovascular diseases in premenopausal women, but is associated with an increased risk of both coronary heart disease and stroke in older postmenopausal women. Studies have shown that activation of the G-p
Externí odkaz:
https://doaj.org/article/51ea22c2ddf44cd7bed4bf746dea173f
Autor:
Xuan Yu, Qiao Zhang, Yan Zhao, Benjamin J Schwarz, John N Stallone, Cristine L Heaps, Guichun Han
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173085 (2017)
Previously, we reported that cAMP/PKA signaling is involved in GPER-mediated coronary relaxation by activating MLCP via inhibition of RhoA pathway. In the current study, we tested the hypothesis that activation of GPER induces coronary artery relaxat
Externí odkaz:
https://doaj.org/article/11756d293f60440486cfbc2c56bd0ab5
Autor:
Irshad Ahmad, Shreyan Gupta, Patricia Faulkner, Destiny Mullens, Micah Thomas, Sharanee P. Sytha, Ivan Ivanov, James J. Cai, Cristine L. Heaps, Annie E. Newell-Fugate
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Coronary artery disease (CAD) is a leading cause of death in women. Epicardial adipose tissue (EAT) secretes cytokines to modulate coronary artery function, and the release of fatty acids from EAT serves as a readily available ene
Externí odkaz:
https://doaj.org/article/0519bec3cfbc427582605dde5718e025
Autor:
Fen Li, Xuan Yu, Claudia K Szynkarski, Cong Meng, Beiyan Zhou, Rola Barhoumi, Richard E White, Cristine L Heaps, John N Stallone, Guichun Han
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64771 (2013)
BACKGROUND:Vascular pathology and dysfunction are direct life-threatening outcomes resulting from atherosclerosis or vascular injury, which are primarily attributed to contractile smooth muscle cells (SMCs) dedifferentiation and proliferation by re-e
Externí odkaz:
https://doaj.org/article/b387206dde0b4a6790824194c2f32243
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H637-H653
The current study reveals that coronary arterioles distal to stenosis display attenuated dilation responses to H2O2 that are restored with endurance exercise training. Enhanced H2O2 dilation after exercise is dependent on Kv and BKCa channels and at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::348de2b166663e9331604b33a0b379f7
https://doi.org/10.1152/ajpheart.00710.2022
https://doi.org/10.1152/ajpheart.00710.2022
Autor:
Trevor S. Self, Anne-Marie Ginn-Hedman, Annie E. Newell-Fugate, Brad R. Weeks, Cristine L. Heaps
Publikováno v:
MethodsX, Vol 8, Iss , Pp 101297- (2021)
We sought to develop a reversible staining protocol using micro-computed tomography (micro-CT) paired with a radiopaque contrast agent that allows for three-dimensional in situ visualization and characterization of atherosclerotic plaques. Atheroscle
Externí odkaz:
https://doaj.org/article/9c5c693b6be94077ac0b3c8ab8f54864
Autor:
Reetu Singh, Cristine L. Heaps, Mariappan Muthuchamy, Michael A. Deveau, Randolph H. Stewart, Glen A. Laine, Ranjeet M. Dongaonkar
Publikováno v:
American journal of physiology. Heart and circulatory physiology.
On the one hand, lymphatic dysfunction induces interstitial edema and inflammation. On the other hand, the formation of edema and inflammation induce lymphatic dysfunction. However, informed by the earlier reports of undetected apoptosis of irradiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d3e67a2c0910ee770f481855bf39b9
https://pubmed.ncbi.nlm.nih.gov/36459446
https://pubmed.ncbi.nlm.nih.gov/36459446
Publikováno v:
Current topics in membranes. 90
Ischemic heart disease is the leading cause of death and a major public health and economic burden worldwide with expectations of predicted growth in the foreseeable future. It is now recognized clinically that flow-limiting stenosis of the large cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23a39b1cce92e6ab96f038e955ea0a31
https://pubmed.ncbi.nlm.nih.gov/36368873
https://pubmed.ncbi.nlm.nih.gov/36368873
Autor:
Rebecca C. Harlow, Reetu Singh, Pooneh Bagher, Cristine L. Heaps, Randolph H. Stewart, Ranjeet M. Dongaonkar
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4fc4fce57f388f9b5166b2f2527beed
https://doi.org/10.1096/fasebj.2022.36.s1.r4804
https://doi.org/10.1096/fasebj.2022.36.s1.r4804
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 319:H915-H926
We have previously reported enhanced Ca2+ sensitivity of coronary arteries that is dependent upon collateral circulation for their blood supply. For the current study, we hypothesized that small collateral-dependent arteries would exhibit an enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2e1d31f30347aa3f6c2a9e85981d187
https://doi.org/10.1152/ajpheart.00384.2020
https://doi.org/10.1152/ajpheart.00384.2020