Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cristina de Castro Spadari"'
Autor:
Fernanda Walt Mendes da Silva de Bastiani, Cristina de Castro Spadari, Jenyffer Kelly Rocha de Matos, Giovanna Cassone Salata, Luciana Biagini Lopes, Kelly Ishida
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
Topical drug administration is frequently used for the treatment of vaginal candidiasis; however, most formulations using this route do not provide prolonged drug release. Our aim was to evaluate the antifungal efficacy of amphotericin B (AMB) and mi
Externí odkaz:
https://doaj.org/article/9ad07abe1de743a98bafb863c59eb9ef
Publikováno v:
Microorganisms, Vol 8, Iss 4, p 613 (2020)
Cryptococcosis is an important opportunistic infection and a leading cause of meningitis in patients with HIV infection. The antifungal pharmacological treatment is limited to amphotericin B, fluconazole and 5- flucytosine. In addition to the limited
Externí odkaz:
https://doaj.org/article/4b8ac33286544148adfa224747e5fcc4
Autor:
Daniel Felipe Freitas De Jesus, Aline Luiza Duarte De Freitas, Isadora Maria De Oliveira, Larissa Costa De Almeida, Rafael Wesley Bastos, Cristina de Castro Spadari, Analy Sales de Azevedo Melo, Daniel de Assis Santos, Letícia Veras Costa-Lotufo, Flavia C. G. Reis, Marcio L. Rodrigues, Hélio Alexandre Stefani, Kelly Ishida
Publikováno v:
Antimicrobial Agents and Chemotherapy.
Cryptococcosis therapy is often limited by toxicity problems, antifungal tolerance, and high costs. Studies approaching chalcogen compounds, especially those containing selenium, have shown promising antifungal activity against pathogenic species.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a93b733ff484bc8df91a646ce2e894c
https://doi.org/10.1128/aac.00759-22
https://doi.org/10.1128/aac.00759-22
Autor:
Kelly Ishida, Cristina de Castro Spadari, Luciana B. Lopes, Fernanda Walt Mendes da Silva de Bastiani
Publikováno v:
International Journal of Nanomedicine. 14:5187-5199
Introduction and objective Previous studies indicate that miltefosine (MFS) may be an alternative as an antifungal agent; however, it presents several adverse effects. Thus, the aim of this study was to produce miltefosine-loaded alginate nanoparticl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e57b77314a8b4ad076b3a4296c6d82e
https://doi.org/10.2147/ijn.s205350
https://doi.org/10.2147/ijn.s205350
Fungal infections cause high morbidity and mortality rates. The current therapeutic arsenal is limited by problems of selectivity, high toxicity, and fungal resistance profiles. Thus, new alternatives for the treatment of fungal diseases are extremel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7b5aef9d8b0ee78139fc593594a09f4
https://doi.org/10.1016/b978-0-12-809633-8.21026-1
https://doi.org/10.1016/b978-0-12-809633-8.21026-1
Autor:
Cristina de Castro Spadari, Thayná Lopes Barreto, Vagner Tebaldi de Queiroz, Walysson Ferreira de Paiva, Sergio Antonio Fernandes, Ângelo de Fátima, Kelly Ishida
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Ketoconazole (KTZ) is an antifungal agent; however, its bioavailability and therapeutic efficacy are reduced by the low aqueous solubility of the drug. Aiming at providing to improve the biopharmaceutical properties of KTZ, we studied the water-solub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbcfadecfa39c60419681538887baad
https://doi.org/10.1016/j.mycmed.2022.101254
https://doi.org/10.1016/j.mycmed.2022.101254
Autor:
Cristina de Castro Spadari, Luciana B. Lopes, Kelly Ishida, Fernanda Walt Mendes da Silva de Bastiani, Giovanna Cassone Salata, Jenyffer Kelly Rocha De Matos
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
Frontiers in Microbiology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Microbiology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Topical drug administration is frequently used for the treatment of vaginal candidiasis; however, most formulations using this route do not provide prolonged drug release. Our aim was to evaluate the antifungal efficacy of amphotericin B (AMB) and mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda35efb4e40b6f3aab3cd68e6eb7db4
Autor:
Gabriel Lima Barros de Araujo, Mirla Anali Bazán Henostroza, Megumi Nishitani Yukuyama, Cristina de Castro Spadari, Nadia Araci Bou-Chacra, Isabela Fernandes de Oliveira, Raimar Löbenberg, Mariana Miyagi, Aline de Souza, Beatriz Rabelo Folchini, Camilla Midori Peroni, Maria Christina Camasmie Peters, Kelly Ishida
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Cryptococcal meningitis is caused by Cryptococcus spp. and predominantly affects patients with acquired immunodeficiency syndrome. However, an increase in the number of nonHIV patients diagnosed with cryptococcosis raises concerns worldwide. The curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a7716a4195cefdc418a6d44fa6728b
https://doi.org/10.1016/j.colsurfa.2021.127631
https://doi.org/10.1016/j.colsurfa.2021.127631
Autor:
Cristina de Castro Spadari, Kelly Ishida, Pietro Bruno Bautista Pisani, Fernanda Walt Mendes da Silva de Bastiani, Analy Salles de Azevedo Melo
Publikováno v:
Archives of microbiology. 202(4)
Cryptococcosis is a common opportunistic infection in patients with advanced HIV infection and may also affect immunocompetent patients. The available antifungal agents are few and other options are needed for the cryptococcosis treatment. In this wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324a3c9d484ae48c4eda60930703d098
https://pubmed.ncbi.nlm.nih.gov/31832690
https://pubmed.ncbi.nlm.nih.gov/31832690