Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cristina Vargiu"'
Autor:
Antonio Toninello, Sebastiano Colombatto, Giulio Clari, Maria Angelica Grillo, Luciana Bordin, Anna Maria Brunati, Mauro Salvi, Cristina Vargiu
Publikováno v:
Biochemical and Biophysical Research Communications. 290:463-468
Cytosolic spermidine/spermine acetyltransferase (SSAT) catalyzes the acetylation of the N 1 -propylamino groups of spermine and spermidine. The enzyme has a very short half-life and is rapidly induced by various stimuli. Once acetylated, these polyam
Autor:
Carlo Cravanzola, Claudia Cabella, Sebastiano Colombatto, Cristina Vargiu, Sabina Belliardo, Maria Angelica Grillo
Publikováno v:
European Journal of Biochemistry. 259:933-938
Agmatine has been proposed as the physiological ligand for the imidazoline receptors. It is not known whether it is also involved in the homoeostasis of intracellular polyamine content. To show whether this is the case, we have studied the effect of
Autor:
Davide Corpillo, Bedino S, Giulia Gardini, Sebastiano Colombatto, Giovanni Testore, Carlo Cravanzola, S.P. Solinas, Maria Angelica Grillo, Claudia Cabella, Cristina Vargiu
Publikováno v:
European Journal of Biochemistry. 268:940-947
Rat hepatocytes in culture take up [14C]-agmatine by both a high-affinity transport system [KM = 0.03 mM; Vmax = 30 pmol x min x (mg protein)-1] and a low-affinity system. The high-affinity system also transports putrescine, but not cationic amino ac
Autor:
Giulio Clari, Giovanni Testore, Maria Angelica Grillo, Sebastiano Colombatto, Cristina Vargiu, Luciana Bordin, Antonio Toninello
Publikováno v:
Biochemical and Biophysical Research Communications. 229:845-851
Casein kinase 2 purified from human erythrocyte cytosol has been found to phosphorylate human spermidine/spermine N 1 -acetyltransferase (SSAT) expressed as a fusion protein in E. coli and purified to homogeneity with a specific activity similar to t
Autor:
Claudia Cabella, Carlo Cravanzola, Giulia Gardini, S.P. Solinas, Giovanni Testore, Sabina Belliardo, Maria Angelica Grillo, Sebastiano Colombatto, Cristina Vargiu, Antonio Toninello
Publikováno v:
Journal of hepatology. 35(4)
Background/Aims : Agmatine, the compound formed by decarboxylation of arginine, is believed to be an endogenous neurotransmitter through interaction with the imidazoline receptors. However, it also appears to regulate rat hepatocyte polyamines by mod
Publikováno v:
The Biochemical journal. 356(Pt 2)
Translational regulation of ornithine decarboxylase (ODC), which catalyses the first step in the biosynthesis of polyamines, appears to be an important mechanism in the strong feedback control as well as in the hypotonic induction of the enzyme. Howe
Autor:
Carlo Cravanzola, Sebastiano Colombatto, Sabina Belliardo, Maria Angelica Grillo, Cristina Vargiu
Publikováno v:
Journal of hepatology. 32(4)
Background/Aims: The human iNOS promoter contains a consensus sequence for binding the hypoxia inducible factor. The aim of this study was to see whether iNOS gene expression is triggered by oxygen tension in rat hepatocytes exposed in vivo to high (
To understand the mechanism involved in the liver zonation of polyamines, we have studied the possible role of oxygen tension. When hepatocytes were cultured at 21% and at 5% oxygen in atmosphere to mimic periportal and perivenous conditions, polyami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8336fbfd4a6f1eaf3d0242ff98511a71
http://hdl.handle.net/2318/6141
http://hdl.handle.net/2318/6141
Publikováno v:
Biochimica et biophysica acta. 1224(3)
In hepatocytes in culture, ornithine aminotransferase activity remained higher when the cells were cultured at low oxygen tension (5%) than at high tension (21%), that is, it was higher in hepatovenous conditions. Northern blot analysis showed that t
Autor:
Lo Persson, Cristina Vargiu
Publikováno v:
FEBS letters. 355(2)
Mammalian spermidine/spermine N1-acetyltransferase (SSAT) was transiently expressed in COS cells. As compared to COS cells transfected with control vector alone, cells transfected with the expression vector containing SSAT cDNA contained lower concen