Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Cristina Travelli"'
Autor:
Greta Cascetta, Giorgia Colombo, Gianmarco Eremita, Joe G. N. Garcia, Marco Vincenzo Lenti, Antonio Di Sabatino, Cristina Travelli
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Autoimmune gastritis (AIG) is an autoimmune disorder characterized by the destruction of gastric parietal cells and atrophy of the oxyntic mucosa which induces intrinsic factor deficiency and hypo-achlorhydria. AIG predominantly affects the antral mu
Externí odkaz:
https://doaj.org/article/3030a441c3e4473898fb3dc8d64db423
Autor:
Marzia Friuli, Christian Sepe, Elisabetta Panza, Cristina Travelli, Irene Paterniti, Adele Romano
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Unhealthy lifestyle habits including a sedentary life, the lack of physical activity, and wrong dietary habits are the major ones responsible for the constant increase of obesity and metabolic disorders prevalence worldwide; therefore, the scientific
Externí odkaz:
https://doaj.org/article/85ec3a17776647cfa959ddc8c6a6a4d6
Autor:
Mario Paolo Colombo, Cristina Travelli, Giorgia Colombo, Sabina Sangaletti, Armando Genazzani
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/55a29c04e07140b9b211431a73f5aa35
Autor:
Mario Paolo Colombo, Joe G N Garcia, Cristina Travelli, Giorgia Colombo, Martina Aliotta, Francesca Fagiani, Natalia Fava, Rita De Sanctis, Ambra A Grolla, Nausicaa Clemente, Paola Portararo, Massimo Costanza, Fabrizio Condorelli, Sabina Sangaletti, Armando A Genazzani
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Nicotinamide phosphoribosyltransferase (NAMPT) is a key intracellular enzyme that participates in nicotinamide adenine dinucleotide (NAD) homeostasis as well as a released cytokine (eNAMPT) that is elevated in inflammatory conditions and i
Externí odkaz:
https://doaj.org/article/c682ddf856af461abc7e0fc0260b779f
Autor:
Francesca Fagiani, Daniele Di Marino, Alice Romagnoli, Cristina Travelli, Davide Voltan, Lorenzo Di Cesare Mannelli, Marco Racchi, Stefano Govoni, Cristina Lanni
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-20 (2022)
Abstract The term “circadian rhythms” describes endogenous oscillations with ca. 24-h period associated with the earth’s daily rotation and light/dark cycle. Such rhythms reflect the existence of an intrinsic circadian clock that temporally orc
Externí odkaz:
https://doaj.org/article/8d1bd25995a6444e8c9d2364bdcf1d27
Autor:
Giorgia Colombo, Gian Paolo Caviglia, Alberto Ravera, Elisa Tribocco, Simone Frara, Chiara Rosso, Cristina Travelli, Armando A. Genazzani, Davide Giuseppe Ribaldone
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundNicotinamide phosphoribosyltransferase (NAMPT) and nicotinic acid phosphoribosyl transferase (NAPRT) are key intracellular enzymes that participate in the biosynthesis on NAD but have also been shown to be released as proinflammatory cytoki
Externí odkaz:
https://doaj.org/article/78e54e08fd944b0cb5358eefb4c505d5
Autor:
Gantsetseg Tumurkhuu, Nancy G. Casanova, Carrie L. Kempf, Duygu Ercan Laguna, Sara M. Camp, Jargalsaikhan Dagvadorj, Jin H. Song, Vivian Reyes Hernon, Cristina Travelli, Erica N. Montano, Jeong Min Yu, Mariko Ishimori, Daniel J. Wallace, Saad Sammani, Caroline Jefferies, Joe G.N. Garcia
Publikováno v:
Journal of Translational Autoimmunity, Vol 6, Iss , Pp 100181- (2023)
Rationale: Effective therapies to reduce the severity and high mortality of pulmonary vasculitis and diffuse alveolar hemorrhage (DAH) in patients with systemic lupus erythematosus (SLE) is a serious unmet need. We explored whether biologic neutraliz
Externí odkaz:
https://doaj.org/article/8b7438a4b64745b39ec0c97c6e32db85
Autor:
Mirco Masi, Enrico Garattini, Marco Bolis, Daniele Di Marino, Luisa Maraccani, Elena Morelli, Ambra A. Grolla, Francesca Fagiani, Emanuela Corsini, Cristina Travelli, Stefano Govoni, Marco Racchi, Erica Buoso
Publikováno v:
Oncogenesis, Vol 9, Iss 12, Pp 1-15 (2020)
Abstract Recent data indicate that receptor for activated C kinase 1 (RACK1) is a putative prognostic marker and drug target in breast cancer (BC). High RACK1 expression is negatively associated with overall survival, as it seems to promote BC progre
Externí odkaz:
https://doaj.org/article/7445495c5de34d7c932fbb6d820d2238
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104147- (2022)
Summary: Nicotinamide phosphoribosyltransferase (NAMPT), alongside being a crucial enzyme in NAD synthesis, has been shown to be a secreted protein (eNAMPT), whose levels are increased in patients affected by immune-mediated disorders. Accordingly, p
Externí odkaz:
https://doaj.org/article/11567ec457f645d5b2d0de452ada8309
Autor:
Giorgia Colombo, Edoardo Luigi Maria Gelardi, Federica Carolina Balestrero, Marianna Moro, Cristina Travelli, Armando A. Genazzani
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Tumour cells modify their cellular metabolism with the aim to sustain uncontrolled proliferation. Cancer cells necessitate adequate amounts of NAD and NADPH to support several enzymes that are usually overexpressed and/or overactivated. Nicotinamide
Externí odkaz:
https://doaj.org/article/58d731c9ede84435a1cb782dd86f6700