Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Cristina Solà-Adell"'
2
Topical administration of DPP-IV inhibitors prevents retinal neurodegeneration in experimental diabetes
Autor: Olga Simó-Servat, Cristina Hernández, Xavier Genís, Joel Sampedro, Patricia Bogdanov, Cristina Solà-Adell, Marta García-Ramírez, Marta Valeri, Rafael Simó
Publikováno v: Diabetologia. 60:2285-2298
The main aims of the present study were: (1) to assess the expression and content of dipeptidyl peptidase IV (DPP-IV) in human and db/db mouse retinas, and in human vitreous fluid; and (2) to determine whether the topical administration of the DPP-IV
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edf5a44e17af7c9903a1d70899027cc
https://doi.org/10.1007/s00125-017-4388-y
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3
SOCS1-derived peptide administered by eye drops prevents retinal neuroinflammation and vascular leakage in experimental diabetes
Autor: Carmen Gomez-Guerrero, Joel Sampedro, Patricia Bogdanov, Carmen Espejo, Jesús Egido, Ignacio Prieto, Cristina Solà-Adell, Marta García-Ramírez, Cristina Hernández, Rafael Simó
Publikováno v: Scientia
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
International Journal of Molecular Sciences, Vol 20, Iss 15, p 3615 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 15
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Current treatments for diabetic retinopathy (DR) target late stages when vision has already been significantly a ected. Accumulating evidence suggests that neuroinflammation plays a major role in the pathogenesis of DR, resulting in the disruption of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7dd23fa2f4d9a7d58166cc4a0510858
https://hdl.handle.net/11351/4586
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4
New insights into the mechanisms of action of topical administration of GLP-1 in an experimental model of diabetic retinopathy
Autor: Olga Simó-Servat, Marta Valeri, Carmen Lagunas, Mireia Turch, Patricia Bogdanov, Hugo Ramos, Cristina Solà-Adell, Rafael Simó, Cristina Hernández, Joel Sampedro
Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Journal of Clinical Medicine
Volume 8
Issue 3
Journal of Clinical Medicine, Vol 8, Iss 3, p 339 (2019)
The main goals of this work were to assess whether the topical administration of glucagon-like peptide-1 (GLP-1) could revert the impairment of the neurovascular unit induced by long-term diabetes (24 weeks) in diabetic mice and to look into the unde
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ea545afcb38e222308b463930ada1c
https://ddd.uab.cat/record/216976
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5
Topical Administration of Bosentan Prevents Retinal Neurodegeneration in Experimental Diabetes
Autor: Olga Simó-Servat, Josep R. Ticó, Bruno Montoro, Marta García-Ramírez, Josep M. Suñé-Negre, Patricia Bogdanov, Cristina Hernández, Rafael Simó, Luis Arias, Hugo Ramos, Joel Sampedro, Cristina Solà-Adell, Vicente Durán, Marta Guerrero
Publikováno v: International Journal of Molecular Sciences
Dipòsit Digital de la UB
Universidad de Barcelona
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3578 (2018)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Experimental evidence suggests that endothelin 1 (ET-1) is involved in the development of retinal microvascular abnormalities induced by diabetes. The effects of ET-1 are mediated by endothelin A- and B-receptors (ETA and ETB). Endothelin B-receptors
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d032925c67f8fda0fbd43023549676f
https://pubmed.ncbi.nlm.nih.gov/30428543
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6
Effects of Liposomal Formulation of Citicoline in Experimental Diabetes-Induced Retinal Neurodegeneration
Autor: Joel Sampedro, Carla Russo, Cristina Solà-Adell, Rafael Simó, Cristina Hernández, Luisa Varela-Sende, Olga Simó-Servat, Patricia Bogdanov
Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 8, p 2458 (2018)
International Journal of Molecular Sciences
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Recercat. Dipósit de la Recerca de Catalunya
instname
Volume 19
Issue 8
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Diabetic retinopathy (DR) has been classically considered a microcirculatory disease of the retina. However, there is growing evidence to suggest that retinal neurodegeneration is also an early event in the pathogenesis of DR. Citicoline has been suc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5369179a44e1c1032891394bec56845
http://www.mdpi.com/1422-0067/19/8/2458
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8
Calcium Dobesilate Prevents Neurodegeneration and Vascular Leakage in Experimental Diabetes
Autor: Cristina Hernández, Rafael Simó, Cristina Solà-Adell, Marta Valeri, Marta García-Ramírez, Joel Sampedro, Patricia Bogdanov, Christian Pasquali
Publikováno v: Current eye research. 42(9)
The mechanisms involved in the reported beneficial effects of Calcium dobesilate monohydrate (CaD) for the treatment of diabetic retinopathy (DR) remain to be elucidated. The main aim of the present study is to examine whether CaD prevents early even
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6323f66b7b45507ea20f266618396c1c
https://pubmed.ncbi.nlm.nih.gov/28574750
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9
Calcium dobesilate prevents the oxidative stress and inflammation induced by diabetes in the retina of db/db mice
Autor: Joel Sampedro, Rafael Simó, Olga Simó-Servat, Cristina Hernández, Marta García-Ramírez, Patricia Bogdanov, Marta Valeri, Christian Pasquali, Cristina Solà-Adell
Publikováno v: Journal of diabetes and its complications. 31(10)
Aim Calcium dobesilate (CaD) is beneficial in early stages of diabetic retinopathy (DR), but its mechanisms of action remains to be elucidated. The aim was to investigate the effect of CaD on proinflammatory cytokines and oxidative stress. Methods db
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddc6d6cb6f236c8bc1f02f59628966f
https://pubmed.ncbi.nlm.nih.gov/28847447
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10
Topical Administration of GLP-1 Receptor Agonists Prevents Retinal Neurodegeneration in Experimental Diabetes
Autor: Ángela M. Valverde, Marta García-Ramírez, José A. Arranz, Lidia Corraliza, Rafael Simó, Ana I. Arroba, Cristina Hernández, Cristina Solà-Adell, Patricia Bogdanov
Publikováno v: Diabetes. 65(1)
Retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy (DR). Since glucagon-like peptide 1 (GLP-1) exerts neuroprotective effects in the central nervous system and the retina is ontogenically a brain-derived tissue, t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ddb2fe1a866d5436c6025f3e76331a
https://pubmed.ncbi.nlm.nih.gov/26384381
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