Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Cristina Sau"'
Autor:
Anna Esteve-Garcia, Estefania Cobos, Cristina Sau, Ariadna Padró-Miquel, Jaume Català-Mora, Pilar Barberán-Martínez, José M. Millán, Gema García-García, Cinthia Aguilera
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction:TULP1 exemplifies the remarkable clinical and genetic heterogeneity observed in inherited retinal dystrophies. Our research describes the clinical and molecular characteristics of a patient manifesting an atypical retinal dystrophy patte
Externí odkaz:
https://doaj.org/article/7498f0855a6149f8b650b1741e4a7da2
Autor:
Macarena Román Alonso, Ariadna Grinyó-Escuer, Santiago Duro-Sánchez, Irene Rius-Ruiz, Marta Bort-Brusca, Marta Escorihuela, Susana Maqueda-Marcos, Sandra Pérez-Ramos, Judit Gago, Vanesa Nogales, Martín Espinosa-Bravo, Vicente Peg, Santiago Escrivá-de-Romaní, Laia Foradada, Laura Soucek, Irene Braña, Vladimir Galvao, Silvia Martín-Lluesma, Ekkehard Moessner, Christian Klein, Elena Garralda, Cristina Saura, Joaquín Arribas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The redirection of T lymphocytes against tumor-associated or tumor-specific antigens, using bispecific antibodies or chimeric antigen receptors (CAR), has shown therapeutic success against certain hematological malignancies. However, this st
Externí odkaz:
https://doaj.org/article/b9b02825ad104b89906a58c00d16e417
Autor:
Oriol Mirallas, Berta Martin-Cullell, Víctor Navarro, Kreina Sharela Vega, Jordi Recuero-Borau, Diego Gómez-Puerto, Daniel López-Valbuena, Clara Salva de Torres, Laura Andurell, Anna Pedrola, Roger Berché, Fiorella Palmas, José María Ucha, Guillermo Villacampa, Alejandra Rezqallah, Judit Sanz-Beltran, Rafael Bach, Sergio Bueno, Cristina Viaplana, Gaspar Molina, Alberto Hernando-Calvo, Juan Aguilar-Company, María Roca, Eva Muñoz-Couselo, Alex Martínez-Martí, Ada Alonso, Simeon Eremiev, Teresa Macarulla, Ana Oaknin, Cristina Saura, Elena Élez, Enriqueta Felip, Ángeles Peñuelas, Rosa Burgos, Patricia Gómez Pardo, Elena Garralda, Josep Tabernero, Sònia Serradell, Sònia Servitja, David Paez, Rodrigo Dienstmann, Joan Carles
Publikováno v:
The Lancet Regional Health. Europe, Vol 46, Iss , Pp 101063- (2024)
Summary: Background: Prognostic factors for ambulatory oncology patients have been described, including Eastern Cooperative Oncology Group (ECOG), tumor stage and malnutrition. However, there is no firm evidence on which variables best predict mortal
Externí odkaz:
https://doaj.org/article/510c740dd59f414d89fc0806c8cb60c4
Autor:
Aglaé Velasco Gonzalez, Boris Buerke, Dennis Görlich, Cristina Sauerland, Manfred Fobker, Astrid Jeibmann, Walter Heindel, Andreas Faldum, Werner Paulus, Harald Kugel
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Knowledge of thrombus behavior and visualization on MRI in acute ischemic stroke is less than optimal. However, MRI sequences could be enhanced based on the typical T1 and T2 relaxation times of the target tissues, which mainly determine the
Externí odkaz:
https://doaj.org/article/fd5f608a472c4cebbec6d59acaaad9b8
Autor:
Tomás Pascual, Aranzazu Fernandez-Martinez, Yash Agrawal, Adam D. Pfefferle, Nuria Chic, Fara Brasó-Maristany, Blanca Gonzàlez-Farré, Laia Paré, Guillermo Villacampa, Cristina Saura, Cristina Hernando, Montserrat Muñoz, Patricia Galván, Xavier Gonzàlez-Farré, Mafalda Oliveira, Miguel Gil-Gil, Eva Ciruelos, Patricia Villagrasa, Joaquín Gavilá, Aleix Prat, Charles M. Perou
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract In this study, we performed genomic analyses of cell cycle and tumor microenvironment changes during and after ribociclib and letrozole or chemotherapy in the CORALLEEN trial. 106 women with untreated PAM50-defined Luminal B early breast can
Externí odkaz:
https://doaj.org/article/3f189cf1ef8a4f74a950d11ff22079b9
Autor:
Pierfranco Conte, Eva Ciruelos, Giuseppe Curigliano, Michelino De Laurentiis, Lucia Del Mastro, Alessandra Gennari, Antonio Llombart, Miguel Martìn, Francesca Poggio, Aleix Prat, Fabio Puglisi, Cristina Saura
Publikováno v:
Breast, Vol 76, Iss , Pp 103742- (2024)
Introduction: Advancements in monoclonal antibodies, tyrosine kinase inhibitors, and antibody drug conjugates (ADCs) have notably enhanced outcomes for metastatic HER2-positive breast cancer patients. Despite the expanding treatment options and clini
Externí odkaz:
https://doaj.org/article/3fd5c1f752464c7f896a88384ff626ee
Autor:
Antonio Llombart-Cussac, José Manuel Pérez-Garcia, Manuel Ruiz Borrego, Pablo Tolosa, Salvador Blanch, Adela Fernández-Ortega, Ander Urruticoechea, Isabel Blancas, Cristina Saura, Beatriz Rojas, Begoña Bermejo, José Ponce Lorenzo, María Gion, Patricia Cortez-Castedo, Elisenda Llabres, Elena Galve, Juan Fernando Cueva, Ana López, José Luis Alonso-Romero, Santiago González-Santiago, Eduardo Martínez de Dueñas, Eva Ciruelos, Griselda Martrat, Petra Gener, Daniel Alcalá-López, Miguel Sampayo-Cordero, Fernando Gómez-Peralta, Javier Cortés
Publikováno v:
EClinicalMedicine, Vol 71, Iss , Pp 102520- (2024)
Summary: Background: Hyperglycaemia is an early and frequent adverse event during alpelisib treatment. METALLICA aimed to evaluate prophylactic metformin to prevent or reduce hyperglycaemia occurrence in patients with HR+/HER2−/PIK3CA-mutated advan
Externí odkaz:
https://doaj.org/article/c5ba8bd9a6864624b463e00529accd71
Autor:
Maria-Josep Carreras, Elena Tomás-Guillén, Anna Farriols, Berta Renedo-Miró, Carolina Valdivia, Jana Vidal, Cristina Saura, Joan Carles, Enriqueta Felip, Maria-Queralt Gorgas, Josep Tabernero, Josep Monterde
Publikováno v:
Current Oncology, Vol 30, Iss 9, Pp 7984-8004 (2023)
Background: Cancer is one of the leading causes of morbidity and mortality in the world. Its growing incidence and prevalence, as well as the advances in diagnostic and treatment tools, motivate an open debate about the economic burden it may place o
Externí odkaz:
https://doaj.org/article/693da0fcbdaa4f0cad78276db01bf51c
Autor:
Guy Jerusalem, Aleix Prat, Roberto Salgado, Mattea Reinisch, Cristina Saura, Manuel Ruiz-Borrego, Petros Nikolinakos, Felipe Ades, Jeiry Filian, Ning Huang, Antonella Mazzei-Abba, Sara M. Tolaney
Publikováno v:
Breast, Vol 72, Iss , Pp 103580- (2023)
Background: Preclinical data suggest synergistic activity with the combination of programmed death-1 and cyclin-dependent kinase 4/6 blockade in oestrogen receptor-positive/human epidermal growth factor 2-negative (ER+/HER2–) breast cancer. The non
Externí odkaz:
https://doaj.org/article/0fa5c73c7ab04a5990f87bbac59a8a3e
Autor:
Jan-Niklas Eckardt, Christoph Röllig, Klaus Metzeler, Peter Heisig, Sebastian Stasik, Julia-Annabell Georgi, Frank Kroschinsky, Friedrich Stölzel, Uwe Platzbecker, Karsten Spiekermann, Utz Krug, Jan Braess, Dennis Görlich, Cristina Sauerland, Bernhard Woermann, Tobias Herold, Wolfgang Hiddemann, Carsten Müller-Tidow, Hubert Serve, Claudia D. Baldus, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan W. Krause, Mathias Hänel, Wolfgang E. Berdel, Christoph Schliemann, Jiri Mayer, Maher Hanoun, Johannes Schetelig, Karsten Wendt, Martin Bornhäuser, Christian Thiede, Jan Moritz Middeke
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-13 (2023)
Abstract Background Increasingly large and complex biomedical data sets challenge conventional hypothesis-driven analytical approaches, however, data-driven unsupervised learning can detect inherent patterns in such data sets. Methods While unsupervi
Externí odkaz:
https://doaj.org/article/c4960d518e3d43029bd21cdce38e327f