Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Cristina Santarossa"'
Autor:
Marc B. Cox, Maulik R. Patel, Pallav D. Patel, Liza Shrestha, Yanlong Kang, Tony Taldone, Erica DaGama Gomes, Monica L. Guzman, Alexander Gozman, Gabriela Chiosis, Ronnie Maharaj, Hediye Erdjument-Bromage, Anna Rodina, Cristina Santarossa, Ronald C. Hendrickson, Pengrong Yan, John Koren, Ari Melnick, Chenghua Yang, Stefan O. Ochiana, Leandro Cerchietti
Publikováno v:
ACS Chemical Biology
Heat shock protein 70 (Hsp70) is a family of proteins with key roles in regulating malignancy. Cancer cells rely on Hsp70 to inhibit apoptosis, regulate senescence and autophagy, and maintain the stability of numerous onco-proteins. Despite these imp