Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cristina Rodriguez-Rodriguez"'
Autor:
Cristina Rodriguez-Rodriguez, Natalia González-Mancha, Ane Ochoa-Echeverría, Rosa Liébana, Isabel Merida
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Background Sorting Nexin 27 (SNX27)-retromer complex facilitates cargo recycling from endosomes to the plasma membrane. SNX27 downregulation in neurons, as the result of Trisomy 21 (T21), has been linked with cognitive deficits due to impair
Externí odkaz:
https://doaj.org/article/d1f8e807d56f4cc99b1b650ca4ae45cd
Autor:
Benjamin Kogos, Leona Cohen-Gould, Cristina Rodriguez-Rodriguez, Vesna Sossi, Nicholas Sobol, Richard Johnson, Douglas C. Miller, J. David Robertson, Paul H. Pevsner
Publikováno v:
AIP Advances, Vol 11, Iss 4, Pp 045035-045035-8 (2021)
Following murine injection, the ultrastructural loci of nanoparticles (NPs) containing lutetium-177 (Lu-177) conjugated to an anti-thrombomodulin antibody (mAb-201b) were determined. The results confirmed prior work localizing NPs using Single Photon
Externí odkaz:
https://doaj.org/article/aeb720cc14f64a70b7cbb7300570f0ea
Autor:
Helena Koniar, Scott McNeil, Luke Wharton, Aidan Ingham, Michiel Van de Voorde, Maarten Ooms, Sathiya Sekar, Cristina Rodríguez-Rodríguez, Peter Kunz, Valery Radchenko, Arman Rahmim, Carlos Uribe, Hua Yang, Paul Schaffer
Publikováno v:
EJNMMI Physics, Vol 11, Iss 1, Pp 1-18 (2024)
Abstract Background Element-equivalent matched theranostic pairs facilitate quantitative in vivo imaging to establish pharmacokinetics and dosimetry estimates in the development of preclinical radiopharmaceuticals. Terbium radionuclides have signific
Externí odkaz:
https://doaj.org/article/94275ecfb96241b988df7d40866a532c
Autor:
Hua, Yang, Chengcheng, Zhang, Zheliang, Yuan, Cristina, Rodriguez-Rodriguez, Andrew, Robertson, Valery, Radchenko, Randy, Perron, Denise, Gendron, Patrick, Causey, Feng, Gao, François, Bénard, Paul, Schaffer
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 26(50)
Targeted alpha-therapy (TAT) has great potential for treating a broad range of late-stage cancers by delivering a focused and lethal radiation dose to tumors. Actinium-225 (
Autor:
Lennart Bohrmann, Christian B M Poulie, Cristina Rodríguez-Rodríguez, Stoyan Karagiozov, Katayoun Saatchi, Matthias M Herth, Urs O Häfeli
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0300466 (2024)
Pretargeting, which is the separation of target accumulation and the administration of a secondary imaging agent into two sequential steps, offers the potential to improve image contrast and reduce radiation burden for nuclear imaging. In recent year
Externí odkaz:
https://doaj.org/article/7c925dcad4404c7fbe79c357116bf78c
Autor:
Luke Wharton, Scott W. McNeil, Helen Merkens, Zheliang Yuan, Michiel Van de Voorde, Gokce Engudar, Aidan Ingham, Helena Koniar, Cristina Rodríguez-Rodríguez, Valery Radchenko, Maarten Ooms, Peter Kunz, François Bénard, Paul Schaffer, Hua Yang
Publikováno v:
Molecules, Vol 28, Iss 7, p 3155 (2023)
Terbium radioisotopes (149Tb, 152Tb, 155Tb, 161Tb) offer a unique class of radionuclides which encompass all four medicinally relevant nuclear decay modalities (α, β+, γ, β−/e−), and show high potential for the development of element-matched
Externí odkaz:
https://doaj.org/article/826b9ea67ada496da4b8a6e86da4e6ce
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-16 (2020)
Abstract Background The discovery and development of new medicines requires high-throughput screening of possible therapeutics in a specific model of the disease. Infrared thermal imaging (IRT) is a modern assessment method with extensive clinical an
Externí odkaz:
https://doaj.org/article/9a53072ad6cd4cc9b916a4909f61098c
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Sorting nexin 27 (SNX27) association to the retromer complex mediates intracellular trafficking of cargoes containing PSD95/Dlg1/ZO-1 (PDZ)-binding C-terminal sequences from endosomes to the cell surface, preventing their lysosomal degradation. Antig
Externí odkaz:
https://doaj.org/article/98c3fa454242482d9e670ec97b7e20ff
Autor:
Caterina F. Ramogida, Andrew K. H. Robertson, Una Jermilova, Chengcheng Zhang, Hua Yang, Peter Kunz, Jens Lassen, Ivica Bratanovic, Victoria Brown, Lily Southcott, Cristina Rodríguez-Rodríguez, Valery Radchenko, François Bénard, Chris Orvig, Paul Schaffer
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-20 (2019)
Abstract Background Actinium-225 (225Ac, t1/2 = 9.9 d) is a promising candidate radionuclide for use in targeted alpha therapy (TAT), though the currently limited global supply has hindered the development of a suitable Ac-chelating ligand and 225Ac-
Externí odkaz:
https://doaj.org/article/c0bdf4239e5f40f0b278e347743bcfe5
Autor:
Judith Leitner, Peter Steinberger, Javier Arranz-Nicolas, Cristina Rodríguez-Rodríguez, Rosa Liébana, Antonia Ávila-Flores, Isabel Mérida
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/d10fb6350d9b436a8939bf0c9e2e3737