Development of bioluminescent reporter Trypanosoma cruzi and bioassay for compound screening

Autor: Cristina Quiroga, Marcelo Incerti, Diego Benitez, Eduardo Manta, Andrea Medeiros, Marcelo A. Comini

Publikováno v: Frontiers in Chemical Biology, Vol 3 (2024)

Trypanosoma cruzi is the etiologic agent of Chagas’ disease, a debilitating and mortal zoonotic illness that threatens the lives of several millions of people in the American continent. The acute phase is underdiagnosed and there is no curative tre

Externí odkaz: https://doaj.org/article/53e87e20ac534bea9c4c565a318587a7

The Detection of Early Reading Performance and Its Relationship with Biopsychosocial Risk Factors in the Study of Learning Difficulties

Autor: Cristina Quiroga Bernardos, Santiago López Gómez, Patricia María Iglesias Souto, Rosa María Rivas Torres, Eva María Taboada Ares

Publikováno v: European Journal of Investigation in Health, Psychology and Education, Vol 12, Iss 8, Pp 1205-1219 (2022)

The study of the multiple processes involved in learning how to read can contribute towards the early detection of good and bad readers. However, it is necessary to take into consideration different biopsychosocial risk factors (pre- and perigestatio

Externí odkaz: https://doaj.org/article/f181c852820947afbeae9d1d69beb8b4

Evaluation of the Anti-Leishmania mexicana and -Trypanosoma brucei Activity and Mode of Action of 4,4′-(Arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)

Autor: Olalla Barreiro-Costa, Cristina Quiroga Lozano, Erika Muñoz, Patricio Rojas-Silva, Andrea Medeiros, Marcelo A. Comini, Jorge Heredia-Moya

Publikováno v: Biomedicines, Vol 10, Iss 8, p 1913 (2022)

Trypanosomiasis and leishmaniasis are neglected infections caused by trypanosomatid parasites. The first-line treatments have many adverse effects, high costs, and are prone to resistance development, hence the necessity for new chemotherapeutic opti

Externí odkaz: https://doaj.org/article/64574da4e3bc4b7791f1ac40d481e673

Mode of action of p-quinone derivatives with trypanocidal activity studied by experimental and in silico models

Autor: Andres Ballesteros-Casallas, Cristina Quiroga, Cecilia Ortiz, Diego Benítez, Pablo A. Denis, David Figueroa, Cristian O. Salas, Jeanluc Bertrand, Ricardo A. Tapia, Patricio Sánchez, Gian Pietro Miscione, Marcelo A. Comini, Margot Paulino

Publikováno v: European journal of medicinal chemistry. 246

Quinones are attractive pharmacological scaffolds for developing new agents for the treatment of different transmissible and non-transmissible human diseases due to their capacity to alter the cell redox homeostasis. The bioactivity and potential mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528fac6051c2088e0b862d680c4925df
https://pubmed.ncbi.nlm.nih.gov/36508970

Diretriz Brasileira de Cardio-oncologia – 2020

Autor: Carlos M. Campos, Paulo M. Hoff, Anelisa Coutinho, Silvia Moulin Ribeiro Fonseca, Vanderson Rocha, Maria Del Pilar Estevez Diz, Diego Ribeiro Garcia, Stephanie Itala Rizk, Ricardo Pavanello, Cesar Higa Nomura, Bruna Morhy Borges Leal Assunção, Cristina Salvadori Bittar, Wilson Mathias Junior, Gustavo Spadaccia dos Santos Fernandes, Marcelo Westerlund Montera, Clarissa Maria de Cerqueira Mathias, Maria Veronica Camara dos Santos, Cecilia Cruz, Marcelo Antônio Cartaxo Queiroga Lopes, Thiago Liguori Feliciano da Silva, Juliana Barbosa Sobral Alves, Manuel Maria Ramos Valente Neto, Carlos Eduardo Negrão, Ana O. Hoff, Roberto Kalil Filho, Maria Carolina Feres de Almeida Soeiro, Marcus Vinícius Bolívar Malachias, Patricia Tavares Felipe Marcatti, Carlos E. Rochitte, Dirceu R. Almeida, Fernando Meton de Alencar Camara Vieira, José Antonio Franchini Ramires, Ariane Vieira Scarlatelli Macedo, Isabela Bispo Santos da Silva Costa, Marianna Deway Andrade Dracoulakis, Laura Testa, Ludhmila Abrahão Hajjar, Aristóteles Comte de Alencar Filho, Yana Novis, Andre Deeke Sasse, Helano Freitas, Luís Beck-da-Silva, Marilia Harumi Higuchi dos Santos Rehder, Silvia Moreira Ayub Ferreira, Ibraim Pinto, Silvia Marinho Martins Alves, Evanius Garcia Wiermann, Maria da Consolação Vieira Moreira, Renata do Val, Juliana Pereira, Antonio Felipe Simão, Carolina Maria Pinto Domingues Carvalho Silva, Veronica Cristina Quiroga Fonseca, João C.N. Sbano, Julia Tizue Fukushima

Publikováno v: Arquivos Brasileiros de Cardiologia, Vol 115, Iss 5, Pp 1006-1043 (2020)
Arquivos Brasileiros de Cardiologia, Volume: 115, Issue: 5, Pages: 1006-1043, Published: 07 DEC 2020
Arquivos Brasileiros de Cardiologia v.115 n.5 2020
Arquivos Brasileiros de Cardiologia
Sociedade Brasileira de Cardiologia (SBC)
instacron:SBC

1. Introduction Cardiovascular disease (CVD) and cancer are currently the leading causes of mortality worldwide and in Brazil.– The recent demographic and epidemiological transitions in Brazil have determined an increase in the population’s life

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af38e6838b151f6905a986391a89036d
http://www.scielo.br/pdf/abc/v115n5/en_1678-4170-abc-115-05-1006.pdf