Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Cristina Purificato"'
Autor:
Daniela Angela Covino, Karolina Elżbieta Kaczor-Urbanowicz, Jing Lu, Maria Vincenza Chiantore, Gianna Fiorucci, Maria Fenicia Vescio, Laura Catapano, Cristina Purificato, Clementina Maria Galluzzo, Roberta Amici, Mauro Andreotti, Maria Cristina Gauzzi, Matteo Pellegrini, Laura Fantuzzi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Macrophages are key targets of human immunodeficiency virus type 1 (HIV-1) infection and main producers of the proinflammatory chemokine CC chemokine ligand 2 (CCL2), whose expression is induced by HIV-1 both in vitro and in vivo. We previously found
Externí odkaz:
https://doaj.org/article/020b0aa2ba574964872b486f143a1608
Autor:
Daniela Latorre, Nadia Pulvirenti, Daniela Angela Covino, Barbara Varano, Cristina Purificato, Gabriella Rainaldi, Maria Cristina Gauzzi, Laura Fantuzzi, Lucia Conti, Gloria Donninelli, Manuela Del Cornò, Michela Sabbatucci, Sandra Gessani, Patrizia Puddu
Publikováno v:
Toxins, Vol 7, Iss 12, Pp 5472-5483 (2015)
Lactoferrin (LF) exhibits a wide range of immunomodulatory activities including modulation of cytokine and chemokine secretion. In this study, we demonstrate that bovine LF (bLF) up-modulates, in a concentration- and time-dependent manner, CCL1 secre
Externí odkaz:
https://doaj.org/article/d173f1c573f647caaccd6c6aa1ee335d
Autor:
Daniela A. Covino, Cristina Purificato, Laura Catapano, Clementina M. Galluzzo, Maria Cristina Gauzzi, Stefano Vella, Eric Lefebvre, Star Seyedkazemi, Mauro Andreotti, Laura Fantuzzi
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3) family members are cytidine deaminases that play crucial roles in innate responses to retrovirus infection. The mechanisms by which some of these enzymes restrict human immun
Externí odkaz:
https://doaj.org/article/1ac93d00312f4001bdce8484eede90de
Autor:
Arturo Ottavio Rinaldi, Isabella Sanseverino, Cristina Purificato, Antonio Cortese, Rosella Mechelli, Silvia Francisci, Marco Salvetti, Enrico Millefiorini, Sandra Gessani, Maria Cristina Gauzzi
Publikováno v:
Toxins, Vol 7, Iss 1, Pp 129-137 (2015)
Vitamin D (vitD) low status is currently considered a main environmental factor in multiple sclerosis (MS) etiology and pathogenesis. VitD and its metabolites are highly hydrophobic and circulate mostly bound to the vitamin D binding protein (DBP) an
Externí odkaz:
https://doaj.org/article/2928ded87b3d40bdade8cc0595f015ca
Autor:
Francesca Spadaro, Serena Cecchetti, Cristina Purificato, Michela Sabbatucci, Franca Podo, Carlo Ramoni, Sandra Gessani, Laura Fantuzzi
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59705 (2013)
HIV-1 envelope glycoprotein gp120 induces, independently of infection, the release of CCL2 from macrophages. In turn, this chemokine acts as an autocrine factor enhancing viral replication. In this study, we show for the first time that phosphoinosit
Externí odkaz:
https://doaj.org/article/beb5d9e6e64144c5918609b08b478601
Autor:
Isabella Sanseverino, Arturo Ottavio Rinaldi, Cristina Purificato, Antonio Cortese, Enrico Millefiorini, Maria Cristina Gauzzi
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6717
Immune mechanisms play an essential role in driving multiple sclerosis (MS) and altered trafficking and/or activation of dendritic cells (DC) were observed in the central nervous system and cerebrospinal fluid of MS patients. Interferon β (IFNβ) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6dc4deda2182d9e3b0d609b991d2ffa
https://doi.org/10.3390/ijms24076717
https://doi.org/10.3390/ijms24076717
Autor:
Gloria Donninelli, Cristina Purificato, Isabella Sanseverino, Maria Cristina Gauzzi, Sandra Gessani
Publikováno v:
Immunobiology. 223:342-347
Dendritic cells (DC) represent an attractive target for therapeutic manipulation of the immune system and enhancement of insufficient immune response in cancer. STAT family members play key roles in the differentiation and activation of DC, a feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9218e431c2e129e28fd6de2edc6239ea
https://doi.org/10.1016/j.imbio.2017.10.049
https://doi.org/10.1016/j.imbio.2017.10.049
Autor:
Sandra Gessani, M. Cristina Gauzzi, Isabella Sanseverino, Lucia Conti, Barbara Varano, Cristina Purificato
Publikováno v:
Immunobiology. 219:503-511
Dendritic cells (DC) are an attractive target for therapeutic manipulation of the immune system to enhance insufficient immune responses, such those occurring in cancer, or to dampen dangerous responses in allergic and autoimmune diseases. Main goal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5ac718b33c370a77327c8f9fd049fc
https://doi.org/10.1016/j.imbio.2014.02.012
https://doi.org/10.1016/j.imbio.2014.02.012
Autor:
Manuela Del Cornò, Gabriella Rainaldi, Barbara Varano, Lucia Conti, Patrizia Puddu, Sandra Gessani, Laura Fantuzzi, Daniela Angela Covino, Daniela Latorre, Nadia Pulvirenti, Gloria Donninelli, Maria Cristina Gauzzi, Michela Sabbatucci, Cristina Purificato
Publikováno v:
Toxins
Volume 7
Issue 12
Pages 5472-5483
Toxins; Volume 7; Issue 12; Pages: 5472-5483
Toxins, Vol 7, Iss 12, Pp 5472-5483 (2015)
Volume 7
Issue 12
Pages 5472-5483
Toxins; Volume 7; Issue 12; Pages: 5472-5483
Toxins, Vol 7, Iss 12, Pp 5472-5483 (2015)
Lactoferrin (LF) exhibits a wide range of immunomodulatory activities including modulation of cytokine and chemokine secretion. In this study, we demonstrate that bovine LF (bLF) up-modulates, in a concentration- and time-dependent manner, CCL1 secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48a9bab1acaaab2a0420559ec477698
Publikováno v:
Immunobiology. 216:1135-1142
Chemokines production in monocytes/macrophages is crucial in modulating immune responses generated through Toll-like receptor (TLR)-mediated recognition of microbes. During microbial onset, multiple pathogen-associated structures can be present at in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683473f40749e4fae90ca016fffa7050
https://doi.org/10.1016/j.imbio.2011.04.005
https://doi.org/10.1016/j.imbio.2011.04.005