Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Cristina Puig"'
Autor:
Sameeha Jilani, Justin D. Saco, Edurne Mugarza, Aleida Pujol-Morcillo, Jeffrey Chokry, Clement Ng, Gabriel Abril-Rodriguez, David Berger-Manerio, Ami Pant, Jane Hu, Rubi Gupta, Agustin Vega-Crespo, Ignacio Baselga-Carretero, Jia M. Chen, Daniel Sanghoon Shin, Philip Scumpia, Roxana A. Radu, Yvonne Chen, Antoni Ribas, Cristina Puig-Saus
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract A major limitation to developing chimeric antigen receptor (CAR)-T cell therapies for solid tumors is identifying surface proteins highly expressed in tumors but not in normal tissues. Here, we identify Tyrosinase Related Protein 1 (TYRP1) a
Externí odkaz:
https://doaj.org/article/cd2701d25f8e48e2a9b53f8ebd1a39b3
Autor:
Inmaculada Pitarch-Castellano, David Hervás, Maria Grazia Cattinari, Eugenia Ibáñez Albert, Mercedes López Lobato, Nancy Carolina Ñungo Garzón, Juan Rojas, Cristina Puig-Ram, Marcos Madruga-Garrido
Publikováno v:
Children, Vol 10, Iss 12, p 1880 (2023)
Spinal muscular atrophy (SMA) is a devastating genetic neurodegenerative disease caused by the insufficient production of Survival Motor Neuron (SMN) protein. It presents different phenotypes with frequent contractures and dislocations, scoliosis, an
Externí odkaz:
https://doaj.org/article/1fa68c40e96a4d09b7aa2772b026b2e6
Autor:
Giulia Parisi, Justin D. Saco, Felix B. Salazar, Jennifer Tsoi, Paige Krystofinski, Cristina Puig-Saus, Ruixue Zhang, Jing Zhou, Gardenia C. Cheung-Lau, Alejandro J. Garcia, Catherine S. Grasso, Richard Tavaré, Siwen Hu-Lieskovan, Sean Mackay, Jonathan Zalevsky, Chantale Bernatchez, Adi Diab, Anna M. Wu, Begoña Comin-Anduix, Deborah Charych, Antoni Ribas
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Adoptive cell transfer (ACT) of T cells for tumor treatment often requires IL-2 administration. Here, the authors show that a modified IL-2 cytokine (NKTR-214) can outperform IL-2 in a melanoma mouse model.
Externí odkaz:
https://doaj.org/article/26da1a14c88d4cdbbb1ebbe52eeb9731
Autor:
Cristina Puig-Saus, Antoni Ribas
Publikováno v:
Immuno-Oncology and Technology, Vol 1, Iss , Pp 19-26 (2019)
First-generation adoptive T-cell transfer (ACT) administering tumor-infiltrating lymphocytes (TILs), and second-generation ACT using autologous T cells genetically modified to express tumor-specific T-cell receptors (TCRs) or chimeric antigen recepto
Externí odkaz:
https://doaj.org/article/e4dd6f3ffa91424886a0595844d2d45e
Autor:
Angel Garcia-Diaz, Daniel Sanghoon Shin, Blanca Homet Moreno, Justin Saco, Helena Escuin-Ordinas, Gabriel Abril Rodriguez, Jesse M. Zaretsky, Lu Sun, Willy Hugo, Xiaoyan Wang, Giulia Parisi, Cristina Puig Saus, Davis Y. Torrejon, Thomas G. Graeber, Begonya Comin-Anduix, Siwen Hu-Lieskovan, Robert Damoiseaux, Roger S. Lo, Antoni Ribas
Publikováno v:
Cell Reports, Vol 19, Iss 6, Pp 1189-1201 (2017)
PD-L1 and PD-L2 are ligands for the PD-1 immune inhibiting checkpoint that can be induced in tumors by interferon exposure, leading to immune evasion. This process is important for immunotherapy based on PD-1 blockade. We examined the specific molecu
Externí odkaz:
https://doaj.org/article/e5b58d91cebc41a38766402ee83a9fa5
Publikováno v:
Reproductive Health Matters, 2018 Dec 01. 26(54), 47-50.
Externí odkaz:
https://www.jstor.org/stable/26605086
Autor:
Yang Pan, John W. Phillips, Beatrice D. Zhang, Miyako Noguchi, Eric Kutschera, Jami McLaughlin, Pavlo A. Nesterenko, Zhiyuan Mao, Nathanael J. Bangayan, Robert Wang, Wendy Tran, Harry T. Yang, Yuanyuan Wang, Yang Xu, Matthew B. Obusan, Donghui Cheng, Alex H. Lee, Kathryn E. Kadash-Edmondson, Ameya Champhekar, Cristina Puig-Saus, Antoni Ribas, Robert M. Prins, Christopher S. Seet, Gay M. Crooks, Owen N. Witte, Yi Xing
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 120, iss 21
Alternative splicing (AS) is prevalent in cancer, generating an extensive but largely unexplored repertoire of novel immunotherapy targets. We describe I soform peptides from R NA splicing for I mmunotherapy target S creening (IRIS), a computational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93609197fd5c544787a244456cbfc71
https://doi.org/10.1073/pnas.2221116120
https://doi.org/10.1073/pnas.2221116120
Autor:
Antoni Ribas, Cristina Puig-Saus, Begoña Comin-Anduix, Jas Singh, Ignacio Baselga-Carretero, Ivan Perez-Garcilazo, Ameya S. Champhekar, Mildred Galvez, Justin D. Saco, Egmidio Medina, Katie M. Campbell, Daniel Karin, Davis Y. Torrejon, Gabriel Abril-Rodriguez
Supplemental Table 3: Differential gene expression analysis between B16 KO and WT tumors in vivo at day 6. Showing genes with q < 0.05 and log2FC > 1 or < -1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e80c04f0c12e19698320b399bff3a9
https://doi.org/10.1158/2767-9764.22545384.v1
https://doi.org/10.1158/2767-9764.22545384.v1
Autor:
Antoni Ribas, Cristina Puig-Saus, Begoña Comin-Anduix, Jas Singh, Ignacio Baselga-Carretero, Ivan Perez-Garcilazo, Ameya S. Champhekar, Mildred Galvez, Justin D. Saco, Egmidio Medina, Katie M. Campbell, Daniel Karin, Davis Y. Torrejon, Gabriel Abril-Rodriguez
Supplementary Figure 1: Impact of PAK4 deletion on the expression of chemokines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76402880d9576bbdd20804bc50e255e1
https://doi.org/10.1158/2767-9764.22545420.v1
https://doi.org/10.1158/2767-9764.22545420.v1
Autor:
Antoni Ribas, Cristina Puig-Saus, Begoña Comin-Anduix, Jas Singh, Ignacio Baselga-Carretero, Ivan Perez-Garcilazo, Ameya S. Champhekar, Mildred Galvez, Justin D. Saco, Egmidio Medina, Katie M. Campbell, Daniel Karin, Davis Y. Torrejon, Gabriel Abril-Rodriguez
Supplementary Figure 8: PAK4 KO in human melanoma cells impairs B-catenin/WNT signalling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c3b389b4b7844b3ae857ac44bbd96c
https://doi.org/10.1158/2767-9764.22545396.v1
https://doi.org/10.1158/2767-9764.22545396.v1