Ursolic Acid Impairs Cellular Lipid Homeostasis and Lysosomal Membrane Integrity in Breast Carcinoma Cells

Autor: Ditte L. Fogde, Cristina P. R. Xavier, Kristina Balnytė, Lya K. K. Holland, Kamilla Stahl-Meyer, Christoffel Dinant, Elisabeth Corcelle-Termeau, Cristina Pereira-Wilson, Kenji Maeda, Marja Jäättelä

Publikováno v: Cells, Vol 11, Iss 24, p 4079 (2022)

Cancer is one of the leading causes of death worldwide, thus the search for new cancer therapies is of utmost importance. Ursolic acid is a naturally occurring pentacyclic triterpene with a wide range of pharmacological activities including anti-infl

Externí odkaz: https://doaj.org/article/6219ca1657984c6bb018bd1bc35834e0

Sambucus nigra flower and berry extracts for food and therapeutic applications: effect of gastrointestinal digestion on in vitro and in vivo bioactivity and toxicity

Autor: Pedro Ferreira-Santos, António Nogueira, Cristina M. R. Rocha, Cristina Pereira Wilson, José A. Teixeira, Cláudia Botelho

Publikováno v: Food & Function. 13:6762-6776

The digestion of S. nigra extracts influences the stability of its phenolic compounds, although they are able to exert their bioactivity. Non-digested and digested extracts have low toxicity and differentiated activity in normal and cancerous cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76818dae9cf56e80f096f959dbf91e7e
https://doi.org/10.1039/d2fo00335j

In Vitro Modulation of Gut Microbiota and Metabolism by Cooked Cowpea and Black Bean

Autor: Catarina Teixeira-Guedes, Tereza Sánchez-Moya, Cristina Pereira-Wilson, Gaspar Ros-Berruezo, Rubén López-Nicolás

Publikováno v: Foods, Vol 9, Iss 7, p 861 (2020)

Legumes are a rich source of a wide range of compounds that may represent an important tool to overcome gut dysbiosis. In this work, the prebiotic potential of two cooked legumes (cowpea and black bean) was investigated in comparison with potato:beef

Externí odkaz: https://doaj.org/article/6a49a2b66b8444069d8b79e7af42b8a8

Ohmic heating polyphenolic extracts from vine pruning residue with enhanced biological activity

Autor: Zlatina Genisheva, Lina F. Ballesteros, Cristina Pereira-Wilson, Meirielly S. Jesus, Ricardo Nuno Correia Pereira, José A. Teixeira, Lucília Domingues, Ana Sofia Carvalho

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Vine Pruning residue was submitted to conventional heating and ohmic heating (OH) for the extraction of bioactive compounds and analyzed for total phenolic content (TPC), polyphenolic profile, antioxidant activity, antimicrobial activity and anticanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd6743613c15d9cd146752662faf249

Ohmic heating extract of vine pruning residue has anti-colorectal cancer activity and increases sensitivity to the chemotherapeutic drug 5-FU

Autor: Lucília Domingues, José A. Teixeira, Cristina Pereira-Wilson, Ana Carvalho, Meirielly S. Jesus

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Foods, Vol 9, Iss 1102, p 1102 (2020)
Foods
Volume 9
Issue 8

Vine pruning residues are by-products of the wine industry that have not received much attention in the past, in spite of being rich in bioactive compounds. In this study, we aimed to test whether an ohmic extract of vine pruning residue (VPE) has an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34918773f9c64ebf5d5740759e850d2d
https://hdl.handle.net/1822/67262