Acute Stress Regulates Sex-Related Molecular Responses in the Human Jejunal Mucosa: Implications for Irritable Bowel Syndrome

Autor: Bruno K. Rodiño-Janeiro, Marc Pigrau, Eloísa Salvo-Romero, Adoración Nieto, Elba Expósito, Ana M. González-Castro, Carmen Galán, Inés de Torres, Teodora Pribic, Laura Hernández, Beatriz Lobo, Marina Fortea, Milagros Gallart, Cristina Pardo-Camacho, Danila Guagnozzi, Javier Santos, Carmen Alonso-Cotoner

Publikováno v: Cells, Vol 12, Iss 3, p 423 (2023)

Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder linked to intestinal barrier dysfunction and life stress. We have previously reported that female sex per se determines an increased susceptibility to intestinal barrier dysfunct

Externí odkaz: https://doaj.org/article/fc20ee996c774f7297c7fdf69a8958bf

The intestinal barrier function and its involvement in digestive disease

Autor: Eloísa Salvo-Romero, Carmen Alonso-Cotoner, Cristina Pardo-Camacho, Maite Casado-Bedmar, María Vicario

Publikováno v: Revista Espanola de Enfermedades Digestivas, Vol 107, Iss 11, Pp 686-696 (2015)

The gastrointestinal mucosal surface is lined with epithelial cells representing an effective barrier made up with intercellular junctions that separate the inner and the outer environments, and block the passage of potentially harmful substances. Ho

Externí odkaz: https://doaj.org/article/e18544a9c96a454993e78503faf45ed4

Overexpression of corticotropin-releasing factor in intestinal mucosal eosinophils is associated with clinical severity in Diarrhea-Predominant Irritable Bowel Syndrome

Autor: María Vicario, Bruno K. Rodiño-Janeiro, Eloísa Salvo-Romero, Cristina Pardo-Camacho, Beatriz Lobo, Ricard Farré, Carmen Alonso-Cotoner, Amanda Rodríguez-Urrutia, Adoracion Nieto, Marc Pigrau, Alejandro Sánchez-Chardi, Marina Fortea, Inés de Torres, Elba Expósito, Fernando Azpiroz, Ana M González-Castro, Danila Guagnozzi, Cristina Martínez, Javier Santos

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports

Corticotropin-releasing factor (CRF) has been identified in intestinal mucosal eosinophils and associated with psychological stress and gut dysfunction. Irritable bowel syndrome (IBS) is commonly characterized by altered intestinal motility, immune a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50d9f9c422ef93f243f5cc19d14abb7
https://ddd.uab.cat/record/253129

Mucosal pathobiology and molecular signature of epithelial barrier dysfunction in the small intestine in irritable bowel syndrome

Autor: María Vicario, Teresa Pérez-Berezo, Cristina Martínez, Eloísa Salvo-Romero, Marina Fortea, Ana M González-Castro, Carmen Alonso-Cotoner, Javier Santos, Cristina Pardo-Camacho

Publikováno v: Journal of Gastroenterology and Hepatology. 32:53-63

Irritable bowel syndrome (IBS) is one of the most prevalent gastrointestinal disorders in developed countries. Its etiology remains unknown; however, a common finding, regardless of IBS subtype, is the presence of altered intestinal barrier. In fact,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ccb37632ce2c95c5e2ae8e4433b8408
https://doi.org/10.1111/jgh.13417

On the origin of Robertsonian fusions in nature: evidence of telomere shortening in wild house mice

Autor: Marta Martínez-Plana, Jacint Ventura, Rosa Ana Sánchez-Guillén, Rita Reig-Viader, Marta Andrés-Nieto, Laia Capilla, Aurora Ruiz-Herrera, Cristina Pardo-Camacho

Publikováno v: Journal of Evolutionary Biology. 28:241-249

The role of telomere shortening to explain the occurrence of Robertsonian (Rb) fusions, as well as the importance of the average telomere length vs. the proportion of short telomeres, especially in nature populations, is largely unexplored. In this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e659e498a4b3fa1b563ddf3b6835d50
https://doi.org/10.1111/jeb.12568