Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Cristina Oliveras-Ferraros"'
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6251 (2009)
Autophagy has been emerging as a novel cytoprotective mechanism to increase tumor cell survival under conditions of metabolic stress and hypoxia as well as to escape chemotherapy-induced cell death. To elucidate whether autophagy might also protect c
Externí odkaz:
https://doaj.org/article/95faa32ea11143c487f53379f3a1a495
Autor:
Javier A. Menendez, Tomás Alarcón, Bruna Corominas-Faja, Jorge Joven, Eugeni López-Bonet, Alejandro Vazquez-Martin, Elisabet Cuyàs, Sílvia Cufí, Begoña Martin-Castillo, Cristina Oliveras-Ferraros
Publikováno v:
Cell Cycle. 12:1166-1179
When fighting cancer, knowledge on metabolism has always been important. Today, it matters more than ever. The restricted cataloging of cancer genomes is quite unlikely to achieve the task of curing cancer, unless it is integrated into metabolic netw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951a1faeff3b62e82add82c62750f982
https://doi.org/10.4161/cc.24479
https://doi.org/10.4161/cc.24479
Autor:
Antonio Segura-Carretero, Enrique Barrajón-Catalán, Eugeni López-Bonet, Vicente Micol, Fedra Luciano-Mateo, Anna Rull, Almudena Pérez-Sánchez, Gerard Aragonès, Carlos Alonso-Villaverde, Salvador Fernández-Arroyo, Laura Tomás-Menor, Vicente Martín-Paredero, Jordi Camps, Isabel Borrás-Linares, Alejandro Vazquez-Martin, Jesús Lozano-Sánchez, Anna Hernández-Aguilera, Cecilia Jiménez-Sánchez, Esther Rodríguez-Gallego, Bruna Corominas-Faja, Cristina Oliveras-Ferraros, Raúl Beltrán-Debón, Jorge Joven, María Herranz-López, Begoña Martin-Castillo, Sílvia Cufí, Javier A. Menendez, Rosa Quirantes-Piné, Marta Riera-Borrull, Anabel García-Heredia
Publikováno v:
Cell Cycle. 12:555-578
Aging can be viewed as a quasi-programmed phenomenon driven by the overactivation of the nutrient-sensing mTOR gerogene. mTOR-driven aging can be triggered or accelerated by a decline or loss of responsiveness to activation of the energy-sensing prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9748748393885d3ba56de53f7798064
https://doi.org/10.4161/cc.23756
https://doi.org/10.4161/cc.23756
Autor:
Bruna Corominas-Faja, Ruth Lupu, Javier A. Menendez, Sílvia Cufí, Luciano Vellon, Jorge Joven, Cristina Oliveras-Ferraros, Alejandro Vazquez-Martin, Octavio J. Menendez
Publikováno v:
Cell Cycle. 12:207-218
Induced pluripotent stem (iPS) cells share some basic properties, such as self-renewal and pluripotency, with cancer cells, and they also appear to share several metabolic alterations that are commonly observed in human tumors. The cancer cells' glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b5948d85ae50d3c7890e726821b0ba
https://doi.org/10.4161/cc.23352
https://doi.org/10.4161/cc.23352
Autor:
Cristina Oliveras-Ferraros, Tamara Sauri-Nadal, Javier A. Menendez, Eugeni López-Bonet, Alejandro Vazquez-Martin, Octavio J. Menendez, Bruna Corominas-Faja, Sílvia Cufí
Publikováno v:
Cell Cycle. 11:4211-4221
Energy- and nutrient-sensing proteins such as AMPK, mTOR and S6K1 are now recognized as novel regulators of mitotic completion in proliferating cells. We investigated the cellular distribution of the Ser2481 autophosphorylation of mTOR, which directl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821ed86ea9de75f2043a4efec3ea442d
https://doi.org/10.4161/cc.22551
https://doi.org/10.4161/cc.22551
Autor:
Javier A. Menendez, Sílvia Cufí, Cristina Oliveras-Ferraros, Begoña Martin-Castillo, Juan Manuel Iglesias, Angel G. Martin, Bruna Corominas-Faja, Alejandro Vazquez-Martin, Eugeni López-Bonet
Publikováno v:
Cell Cycle. 11:4020-4032
The rate of inherent resistance to single-agent trastuzumab in HER2-overexpressing metastatic breast carcinomas is impressive at above 70%. Unfortunately, little is known regarding the distinctive genetic signatures that could predict trastuzumab ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c8a213dd9fee8f9614a8703ab687c3
https://doi.org/10.4161/cc.22225
https://doi.org/10.4161/cc.22225
Autor:
Sílvia Cufí, Alejandro Vazquez-Martin, Javier A. Menendez, Begoña Martin-Castillo, Bruna Corominas-Faja, Jorge Joven, Cristina Oliveras-Ferraros
Publikováno v:
Cell Cycle. 11:2782-2792
Glucose deprivation is a distinctive feature of the tumor microecosystem caused by the imbalance between poor supply and an extraordinarily high consumption rate. The metabolic reprogramming from mitochondrial respiration to aerobic glycolysis in can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d7d40d3e168bde30c203c361221b0e3
https://doi.org/10.4161/cc.20948
https://doi.org/10.4161/cc.20948
Autor:
Alejandro Vazquez-Martin, Antonio Segura-Carretero, Javier A. Menendez, Bruna Corominas-Faja, Jorge Joven, Begoña Martin-Castillo, Rosa Quirantes-Piné, Sílvia Cufí, Cristina Oliveras-Ferraros, Vicente Micol
Publikováno v:
ResearcherID
Scopus-Elsevier
Aging (Albany NY)
Scopus-Elsevier
Aging (Albany NY)
Metabolomic fingerprint of breast cancer cells treated with the antidiabetic drug metformin revealed a significant accumulation of 5-formimino-tetrahydrofolate, one of the tetrahydrofolate forms carrying activated one-carbon units that are essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecebcc80052de53187ab8da5a3be8df
https://doi.org/10.18632/aging.100472
https://doi.org/10.18632/aging.100472
Autor:
Alegría Carrasco-Pancorbo, Antonio Segura-Carretero, Alberto Fernández-Gutiérrez, Cristina Oliveras-Ferraros, Javier A. Menendez, Rocío García-Villalba
Publikováno v:
Journal of Chromatography B. 898:69-77
Polyphenols from extra virgin olive oil (EVOO), a main component of the Mediterranean diet, have demonstrated repeatedly anti-tumor activity in several in vitro and in vivo studies. However, little is known about the efficiency of the absorption proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671b23ccb684839e24e0e8ec5fa9ab89
https://doi.org/10.1016/j.jchromb.2012.04.021
https://doi.org/10.1016/j.jchromb.2012.04.021
Autor:
Rosa Quirantes, Vicente Micol, Sílvia Cufí, Cristina Oliveras-Ferraros, Jorge Joven, Javier A. Menendez, Joaquim Bosch-Barrera, Alejandro Vazquez-Martin, Antonio Segura-Carretero, Luciano Vellon, Begoña Martin-Castillo, Sonia Del Barco
Publikováno v:
Cell Cycle. 11:1235-1246
We have tested the hypothesis that the antidiabetic biguanide metformin can be used to manipulate the threshold for stress-induced senescence (SIS), thus accelerating the onset of cancer-protective cellular senescence in response to oncogenic stimuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24ec2b5bcc58e4f58838476b5003a18
https://doi.org/10.4161/cc.11.6.19665
https://doi.org/10.4161/cc.11.6.19665