Zobrazeno 1 - 10 of 36 pro vyhledávání: '"Cristina Northfleet de Albuquerque"'
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Akademický článek
Genotoxicity Revaluation of Three Commercial Nitroheterocyclic Drugs: Nifurtimox, Benznidazole, and Metronidazole
Autor: Annamaria Buschini, Lisa Ferrarini, Susanna Franzoni, Serena Galati, Mirca Lazzaretti, Francesca Mussi, Cristina Northfleet de Albuquerque, Tânia Maria Araújo Domingues Zucchi, Paola Poli
Publikováno v: Journal of Parasitology Research, Vol 2009 (2009)
Nitroheterocyclic compounds are widely used as therapeutic agents against a variety of protozoan and bacterial infections. However, the literature on these compounds, suspected of being carcinogens, is widely controversial. In this study, cytotoxic a
Externí odkaz: https://doaj.org/article/402fb07236374fe98421e96be2cc5d9e
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2
CHEMICAL RISK CRIAÇÃO DE UM JOGO DIDÁTICO PARA O ENSINO DE BIOSSEGURANÇA / CHEMICAL RISK CREATION OF A DIDACTIC GAME FOR TEACHING BIOSAFETY
Autor: Gledson Kleiton da Silva, Cristina Northfleet de Albuquerque, Wilker Alves de Moura, Luiz Fernando de Souza, Alvaro Gabriele Rodrigues, Daniel Martins da Silva Oliveira
Publikováno v: Brazilian Journal of Development. 7:23764-23772
O jogo Chemical Risk e um projeto didatico que visa demonstrar a utilizacao de jogos na educacao atraves do desenvolvimento de um jogo digital, cujo principal objetivo e a fixacao dos principais conceitos de biosseguranca. Refere-se a uma reflexao so
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b43aebf2e2854ae7b69b57339277670d
https://doi.org/10.34117/bjdv7n3-200
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3
Synthesis and evaluation trypanosomicidal activity of new derivatives of megazol
Autor: Flávia Silva Damasceno, Helena Braga Leites, Ronaldo Zucatelli Mendonça, Ariel Mariano Silber, Cristina Northfleet de Albuquerque
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Objective : This work aims at the synthesis of megazol analogs with antitrypanosomicidal activity. Chagas’disease is caused by Trypanosoma cruzi and is a debilitating disease that has both acute and chronic forms. Many South Americans suffer from t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229e374ed0fbd907dd43386a5446321c
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4
Genotoxicity Revaluation of Three Commercial Nitroheterocyclic Drugs: Nifurtimox, Benznidazole, and Metronidazole
Autor: Paola Poli, Mirca Lazzaretti, Cristina Northfleet de Albuquerque, Susanna Franzoni, Lisa Ferrarini, Annamaria Buschini, Serena Galati, Tânia Maria Araújo Domingues Zucchi, Francesca Mussi
Publikováno v: Journal of Parasitology Research, Vol 2009 (2009)
Journal of Parasitology Research
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nitroheterocyclic compounds are widely used as therapeutic agents against a variety of protozoan and bacterial infections. However, the literature on these compounds, suspected of being carcinogens, is widely controversial. In this study, cytotoxic a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3844898b74fdd4e81c1b1351773ff9f
https://doi.org/10.1155/2009/463575
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5
Trypanocidal nitroimidazole derivatives: Relationships among chemical structure and genotoxic activity
Autor: Giorgio Pelosi, Carlo Rossi, Tânia Maria Araújo Domingues Zucchi, Cristina Northfleet de Albuquerque, Federica Giordani, Claudia Pellacani, Annamaria Buschini, Paola Poli
Publikováno v: Biochemical Pharmacology. 73:1537-1547
Human American trypanosomiasis is resurgent in Latin Americans, and new drugs are urgently required as current medications suffer from a number of drawbacks. Some nitroheterocycles have been demonstrated to exert a potent activity against trypanosome
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4791d2f8d888362a6558c7186ad6fe
https://doi.org/10.1016/j.bcp.2007.01.024
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7
Cytotoxic and genotoxic effects of megazol, an anti-Chagas’ disease drug, assessed by different short-term tests
Autor: Annamaria Buschini, Paola Poli, Renato A. Mortara, Carlo Rossi, Michele A. de Mello, Cristina Northfleet de Albuquerque, Solange da Silva, Tânia Maria Araújo Domingues Zucchi
Publikováno v: Biochemical Pharmacology. 64:1617-1627
Cyto- and genotoxicity induced by drugs can limit the dose and duration of treatment, can adversely affect patient quality of life, and may be life-threatening. Two drugs are currently being used for treatment of the acute phase of Chagas' disease an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60864a7a0a638c6d32123ba83f6ddfc5
https://doi.org/10.1016/s0006-2952(02)01390-4
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8
Affinity partitioning of glucose-6-phosphate dehydrogenase and hexokinase in aqueous two-phase systems with free triazine dye ligands
Autor: Yan Xu, Adalberto Pessoa, Cristina Northfleet de Albuquerque, Michele Vitolo
Publikováno v: Journal of Chromatography B. 780:53-60
The partitioning of glucose-6-phosphate dehydrogenase (G6PDH) (E.C. 1.1.1.49) and hexokinase (E.C. 2.7.1.1) in polyethylene glycol (PEG)-hydroxypropyl starch (PES) and PEG-phosphate aqueous two-phase systems was investigated with free triazine dyes,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b967151301c9ab6106b4b71d518ea7
https://doi.org/10.1016/s1570-0232(02)00409-9
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9
Chemical Risk: Criação de um Jogo Didático para o Ensino de Biossegurança
Autor: Cristina Northfleet de Albuquerque, Gledson Kleiton da Silva, Wilker Alves de Moura, Luiz Fernando de Souza, Alvaro Gabriele Rodrigues, Daniel Martins da Silva Oliveira
Publikováno v: Revista de Graduação USP. 1:69
O Chemical Risk é um projeto didático que visa a demonstrar a utilização de jogos na educação por meio do desenvolvimento de um jogo digital, cujo objetivo primeiro é a fixação dos principais conceitos de Biossegurança. Tal proposta promove
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57f41b5bb7985c4035795d7529562c8e
https://doi.org/10.11606/issn.2525-376x.v1i2p69-74
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10
Purification of glucose-6-phosphate dehydrogenase from baker's yeast in aqueous two-phase systems with free triazine dyes as affinity ligands
Autor: Yan, Xu, Michele, Vitolo, Cristina Northfleet, de Albuquerque, Adalberto, Pessoa
Publikováno v: Applied biochemistry and biotechnology.
To improve the selectivity of glucose-6-phosphate dehydrogenase (G6PDH) extraction by an aqueous two-phase system, a simple and inexpensive affinity aqueous two-phase system using unbound reactive triazine dyes as ligands was introduced. In a polyeth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9582cceed40216555ab786d27c737144
https://pubmed.ncbi.nlm.nih.gov/12721423
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