Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Cristina Nazarov"'
Autor:
Jacqueline Surls, Cristina Nazarov-Stoica, Margaret Kehl, Cara Olsen, Sofia Casares, Teodor-D Brumeanu
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38733 (2012)
Cell signaling for T-cell growth, differentiation, and apoptosis is initiated in the cholesterol-rich microdomains of the plasma membrane known as lipid rafts. Herein, we investigated whether enrichment of membrane cholesterol in lipid rafts affects
Externí odkaz:
https://doaj.org/article/77aa4cc9ba23459da0260ca447f65535
Autor:
Beverly Duncan, Cristina Nazarov-Stoica, Jacqueline Surls, Margaret Kehl, Constantin Bona, Sofia Casares, Teodor-D Brumeanu
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11427 (2010)
Double negative CD3(+)4(-)8(-) TCR alphabeta splenic cells (DNCD3) can suppress the immune responses to allo and xenografts, infectious agents, tumors, and some autoimmune disorders. However, little is known about their role in autoimmune diabetes, a
Externí odkaz:
https://doaj.org/article/7abd204a81314af0970b09a662bd6583
Autor:
Jacqueline Surls, Margaret Kehl, Constantin A. Bona, Teodor-D. Brumeanu, Cristina Nazarov-Stoica, Sofia Casares
Publikováno v:
The Open Autoimmunity Journal. 1:64-78
The CD4 + 25 hi Foxp3 + T regulatory (T-reg) cells are naturally-born in thymus and they are critical for maintain- ing the tolerance to self and non-self antigens. Foxp3 is the master-regulatory gene of development and function of this cell subset.
Autor:
Teodor-D. Brumeanu, Sofia Casares, Cristina Nazarov-Stoica, Jacqueline Surls, Constantin A. Bona
Publikováno v:
The Journal of Immunology. 182:102-110
Naturally occurring CD4+25highFoxp3+ T regulatory (T-reg) cells are critical for maintaining tolerance to self and non-self Ags. The Foxp3 master-regulatory gene and CD28 costimulation are both required for thymic development and suppressogenic funct
Publikováno v:
Stem Cell Research & Therapy
Introduction Mesenchymal stem cells (MSCs) have immunosuppressive activity. They do not induce allospecific T cell responses, making them promising tools for reducing the severity of graft versus host disease (GVHD) as well as treating various immune
Publikováno v:
Vaccine. 28(45)
The T-regulatory (T-reg) cells restrict the T-cell functions in various viral infections including influenza infection. However little is known about the effect of T-regs in influenza vaccination. Herein, we found that immunization of BALB/c mice wit
Autor:
Teodor-D. Brumeanu, Beverly Duncan, Jacqueline Surls, Cristina Nazarov–Stoica, Constantin A. Bona, Margaret Kehl, Sofia Casares
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 7, p e11427 (2010)
PLoS ONE, Vol 5, Iss 7, p e11427 (2010)
BACKGROUND Double negative CD3(+)4(-)8(-) TCR alphabeta splenic cells (DNCD3) can suppress the immune responses to allo and xenografts, infectious agents, tumors, and some autoimmune disorders. However, little is known about their role in autoimmune
Autor:
Sofia Casares, Anca Preda-Pais, Cristina Nazarov–Stoica, Constantin A. Bona, Teodor-D. Brumeanu
Publikováno v:
Molecular immunology. 44(4)
The GM gangliosides and cholesterol components of plasma membrane lipid rafts play an important role in the recruitment and signaling of protein receptors in eukaryotic cells. Herein, we have analyzed at the single-cell level the partitioning and int
Publikováno v:
The Journal of Immunology. 186:147.7-147.7
Multipotent stromal cells (MSCs) are known to have immunosuppressive activity. They do not induce allospecific T cell responses, making them promising tools for reducing the severity of graft vs host disease. Although the immunosuppressive effect has