Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Cristina Nastasă"'
Autor:
Daniel Ungureanu, Brîndușa Tiperciuc, Cristina Nastasă, Ioana Ionuț, Gabriel Marc, Ilioara Oniga, Ovidiu Oniga
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 89 (2024)
Antimicrobial resistance is an increasing problem for global public health. One of the strategies to combat this issue is the synthesis of novel antimicrobials through rational drug design based on extensive structure–activity relationship studies.
Externí odkaz:
https://doaj.org/article/22a1bdf21a754f7191e4cba73c5d0191
Autor:
Raluca Pele, Gabriel Marc, Ioana Ionuț, Cristina Nastasă, Ionel Fizeșan, Adrian Pîrnău, Laurian Vlase, Mariana Palage, Smaranda Oniga, Ovidiu Oniga
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 136 (2022)
The development of hybrid molecules with significant human therapeutic properties is one of the main approaches of pharmaceutical research. One of the most important pharmacophores is the quinazolin-4(3H)-one heterocycle moiety, due to its wide range
Externí odkaz:
https://doaj.org/article/ae25de6798294003950861cf13338914
Autor:
Raluca Pele, Gabriel Marc, Anca Stana, Ioana Ionuț, Cristina Nastasă, Brîndușa Tiperciuc, Ilioara Oniga, Adrian Pîrnău, Laurian Vlase, Ovidiu Oniga
Publikováno v:
Molecules, Vol 27, Iss 8, p 2599 (2022)
Considering the important damage caused by the reactive oxygen (ROS) and nitrogen (RNS) species in the human organism, the need for new therapeutic agents, with superior efficacy to the known natural and synthetic antioxidants, is crucial. Quinazolin
Externí odkaz:
https://doaj.org/article/785b1318758949fda61991cc4c0219df
Autor:
Dominique Serge Ngono Bikobo, Dan C. Vodnar, Anca Stana, Brînduşa Tiperciuc, Cristina Nastasă, Maxime Douchet, Ovidiu Oniga
Publikováno v:
Journal of Saudi Chemical Society, Vol 21, Iss 7, Pp 861-868 (2017)
A series of 10 new N-phenyl-4-(4-(thiazol-2-yl)-phenyl)-thiazol-2-amine derivatives (3a–j) and 4 new 5-(2-(phenylamino)-thiazol-4-yl)-benzamide ethers (3′a–d) were synthesized from 4-(2-phenylamino)-thiazol-4-yl)-benzothioamide and 2-hydroxy-5-
Externí odkaz:
https://doaj.org/article/8badf483ba8c49c29452718ab6bc9264
Autor:
Radu Tamaian, Augustin Moţ, Radu Silaghi-Dumitrescu, Ioana Ionuţ, Anca Stana, Ovidiu Oniga, Cristina Nastasă, Daniela Benedec, Brînduşa Tiperciuc
Publikováno v:
Molecules, Vol 20, Iss 12, Pp 22188-22201 (2015)
Lipophilicity, as one of the most important physicochemical parameters of bioactive molecules, was investigated for twenty-two thiazolyl-carbonyl-thiosemicarbazides and thiazolyl-azoles. The determination was carried out by reversed-phase thin-layer
Externí odkaz:
https://doaj.org/article/59b05757bedf4c8aa209aecad033bf21
Publikováno v:
Molecules, Vol 20, Iss 9, Pp 17325-17338 (2015)
New series of hydrazones 5–18 were synthesized, in good yields, by reacting 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbohydrazide with differently substituted benzaldehyde. The resulting compounds were characterized via elemental analysis
Externí odkaz:
https://doaj.org/article/53cdafb5d5e9490d961ceec89726e776
Publikováno v:
Medicina, Vol 55, Iss 4, p 85 (2019)
Background and objectives: Cancer represents the miscommunication between and within the body cells. The mutations of the oncogenes encoding the MAPK pathways play an important role in the development of tumoral diseases. The mutations of KRAS and BR
Externí odkaz:
https://doaj.org/article/0af6fbf03fa34314b65576a3bc7060fd
Publikováno v:
Bangladesh Journal of Pharmacology, Vol 10, Iss 3, Pp 716-717 (2015)
No abstract is available
Externí odkaz:
https://doaj.org/article/49d8adde7c144c8e9bd7db3ca91291b3
Autor:
Anca Stana, Alexandra Enache, Dan Cristian Vodnar, Cristina Nastasă, Daniela Benedec, Ioana Ionuț, Cezar Login, Gabriel Marc, Ovidiu Oniga, Brîndușa Tiperciuc
Publikováno v:
Molecules, Vol 21, Iss 11, p 1595 (2016)
In the context of the dangerous phenomenon of fungal resistance to the available therapies, we present here the chemical synthesis of a new series of thiazolyl-triazole Schiff bases B1–B15, which were in vitro assessed for their anti-Candida potent
Externí odkaz:
https://doaj.org/article/fb2e8e165e904c89bbd942b9703458cb
Autor:
Remus Moldovan, Viorica Leordean Lazar, Ovidiu Oniga, Cristina Nastasă, Simona Clichici, Andra Clichici, Ramona Simedrea, Pharmacy, Victor Babeş street, Ro , Cluj-Napoca, Romania\\', Irina C. Irina C. Chiș
Publikováno v:
Studia Universitatis Babeș-Bolyai Chemia. 63:103-112