Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Cristina Miglis"'
Autor:
Sean N. Avedissian, Michelle Pham, Medha D. Joshi, Marc H. Scheetz, Ashkan Salamatipour, Jeffin M. Panickar, Khrystyna Hlukhenka, Cristina Miglis, Athanasios Chalkias, Theodoros Xanthos
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 539 (2021)
While the antiarrhythmic drug amiodarone is commonly used in clinical practice, it has a narrow therapeutic index that can lead to acute overdose. One proposed method to deal with this toxicity is lipid emulsion therapy, which may potentially quench
Externí odkaz:
https://doaj.org/article/7b5602c0c2e54d4982f432961768f75d
Autor:
Theodoros Xanthos, Ashkan Salamatipour, Medha D. Joshi, Marc H. Scheetz, Khrystyna Hlukhenka, Michelle Pham, Jeffin M. Panickar, Athanasios Chalkias, Cristina Miglis, Sean N. Avedissian
Publikováno v:
Pharmaceutics, Vol 13, Iss 539, p 539 (2021)
Pharmaceutics
Volume 13
Issue 4
Pharmaceutics
Volume 13
Issue 4
While the antiarrhythmic drug amiodarone is commonly used in clinical practice, it has a narrow therapeutic index that can lead to acute overdose. One proposed method to deal with this toxicity is lipid emulsion therapy, which may potentially quench
Autor:
Sean N. Avedissian, Michael T. Yin, Christine J. Kubin, Nathaniel J. Rhodes, Michelle Prickett, Serge Cremers, Cristina Miglis, Marc H. Scheetz
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 38:730-738
Objectives Polymyxin B pharmacokinetics (PK) in adults with cystic fibrosis (CF) are not well described. The goals of this pilot study were to identify a PK model for patients with CF receiving polymyxin B with exploration of covariate relationships
Autor:
Chao Qi, Teresa R. Zembower, J. Nicholas O'Donnell, Christina Silkaitis, Cristina Miglis, Marc H. Scheetz, Sarah H. Sutton, Elise M. Gilbert, Nathaniel J. Rhodes, Page E. Crew
Publikováno v:
American Journal of Infection Control. 46:270-275
Background The purpose of this single-center, ecologic study is to characterize the relationship between facility-wide (FacWide) antibiotic consumption and incident health care facility-onset Clostridium difficile infection (HO-CDI). Methods FacWide
Autor:
Nathaniel J. Rhodes, Anil Gulati, Thomas P. Lodise, Sean N. Avedissian, Medha D. Joshi, J. Nicholas O'Donnell, Gwendolyn M Pais, Walter C. Prozialeck, Brooke Griffin, Cristina Miglis, Marc H. Scheetz, Jiajun Liu, Lejla Catovic, Cameron Cluff
Publikováno v:
International Journal of Antimicrobial Agents. 51:239-243
Background Although the exposure-dependent efficacy thresholds of vancomycin have been probed, less is known about acute kidney injury (AKI) thresholds for this drug. Sensitive urinary biomarkers, such as kidney injury molecule 1 (KIM-1), have shown
Publikováno v:
International Journal of Antimicrobial Agents. 53:95-97
The quantitative importance of active antimicrobial treatment relative to other modifiable and non-modifiable risk factors for mortality has not been well defined in the literature. Here we quantify the impact of active antimicrobial treatment on mor
Autor:
David P. Nicolau, Joseph L. Kuti, Nathaniel J. Rhodes, Cristina Miglis, Marc H. Scheetz, Scott A. Van Wart
Publikováno v:
International Journal of Antimicrobial Agents. 50:487-490
The quantitative impact of severity of illness on pharmacodynamic thresholds is poorly defined. We used a robust cefepime outcomes cohort and previously identified pharmacodynamic breakpoints of 68% [pharmacokinetic (PK) model 1] and 74% (PK model 2)
Autor:
Erik Skoglund, Jamie L. Wagner, Cristina Miglis, Maria R. Advincula, Marc H. Scheetz, Milena M. McLaughlin
Publikováno v:
Journal of Global Antimicrobial Resistance. 13:261-263
Carbapenem minimum inhibitory concentration (MICs) are known to predict outcomes for patients with Gram-negative bacteraemia. However, limited data exist on how MICs influence such outcomes when organisms are classified as carbapenem-resistant. The p
Autor:
Brian Nelson, Cristina Miglis, Serge Cremers, Christine J. Kubin, Sean N. Avedissian, Marc H. Scheetz, Nathaniel J. Rhodes, Michael T. Yin
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
A retrospective study was conducted in hospitalized patients receiving intravenous polymyxin B who underwent therapeutic drug monitoring during treatment. The aim of this study was to assess the population pharmacokinetics (PK) of intravenous polymyx
Autor:
Michael T. Yin, Manjunath P. Pai, Sean N. Avedissian, Cristina Miglis, Christine J. Kubin, Nathaniel J. Rhodes, Marc H. Scheetz, Brian Nelson
Polymyxin B (PB) has reemerged as a common treatment against multidrug-resistant Gram-negative pathogens. However, nephrotoxicity remains a significant dose-limiting side effect, and contemporary pharmacokinetic (PK) data are limited. This study soug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4757a58ddd95f42a012945fdf759fc16
https://europepmc.org/articles/PMC5826159/
https://europepmc.org/articles/PMC5826159/