Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Cristina Martínez-Ohárriz"'
Autor:
Cristian Reboredo, Carlos J. González-Navarro, Ana Luisa Martínez-López, Cristina Martínez-Ohárriz, Bruno Sarmento, Juan M. Irache
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 39 (2021)
Zein, the major storage protein from corn, has a GRAS (Generally Regarded as Safe) status and may be easily transformed into nanoparticles, offering significant payloads for protein materials without affecting their stability. In this work, the capab
Externí odkaz:
https://doaj.org/article/2e561eecd9194f5dac43e592a7607fd7
Akademický článek
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Akademický článek
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Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15367
The unexpected dissolution behaviour of amorphous diflunisal-chitosan solid dispersions (kneading method) with respect to the crystalline co-evaporated systems is the starting point of this research. This work is an in-depth study of the diflunisal r
Autor:
Qonita Kurnia, Anjani, Juan, Domínguez-Robles, Emilia, Utomo, María, Font, María Cristina, Martínez-Ohárriz, Andi Dian, Permana, Álvaro, Cárcamo-Martínez, Eneko, Larrañeta, Ryan F, Donnelly
Publikováno v:
Pharmaceuticals
Inclusion complexation of rifampicin (RIF) with several types of cyclodextrins (βCD, hydroxypropyl-βCD, γCD, hydroxypropyl-γCD) in aqueous solutions at different pH values was investigated to assess the interactions between RIF and cyclodextrins
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss, Pp 100104-(2021)
Dadun. Depósito Académico Digital de la Universidad de Navarra
Universitat Oberta de Catalunya (UOC)
International Journal of Pharmaceutics: X
Dadun. Depósito Académico Digital de la Universidad de Navarra
Universitat Oberta de Catalunya (UOC)
International Journal of Pharmaceutics: X
Camptothecin (CPT) exhibits a number of challenges for its oral administration, including a low aqueous solubility, a lactone ring susceptible to hydrolysis, and an affinity to the intestinal P-gp. The aim of this work was to evaluate nanoparticles f
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 16119
Gemfibrozil (GEM) is a hypolipidemic agent, which is effective in reducing serum cholesterol and triglyceride levels. Complexation of GEM with native β-cyclodextrin (β-CD) and with the derivatives hydroxypropyl-β- and randomly methylated β-CD (HP
Akademický článek
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Autor:
Juan M. Irache, José L. Vizmanos, Yiyan He, Zhongwei Gu, María Cristina Martínez-Ohárriz, Paula Aranaz, David Lucio
Publikováno v:
International Journal of Pharmaceutics. 547:97-105
The aim of this work was to prepare and evaluate cyclodextrins-modified poly(anhydride) nanoparticles to enhance the oral administration of glibenclamide. A conjugate polymer was synthesized by incorporating hydroxypropyl-β-cyclodextrin to the backb
Autor:
Egoitz Muñoz, María Cristina Martínez-Ohárriz, Juan M. Irache, Maite Solas, María J. Ramírez, Lina Clara Gayoso e Almendra Ibiapina Moreno, Nereide S. Santos-Magalhães
Publikováno v:
International Journal of Pharmaceutics. 543:245-256
Nimodipine may be of interest to treat behavioral alterations and memory deficits. However, its oral administration is hampered by a low bioavailability. The aim of this work was to develop pegylated nanoparticles as oral carriers of nimodipine and t