Potential PET tracers for imaging of tumor-associated macrophages

Autor: Bruna Fernandes, Paula Kopschina Feltes, Carolina Luft, Luiza Reali Nazario, Cristina Maria Moriguchi Jeckel, Ines F. Antunes, Philip H. Elsinga, Erik F. J. de Vries

Publikováno v: EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-19 (2022)

Abstract The increasing incidence of cancer over the years is one of the most challenging problems in healthcare. As cancer progresses, the recruitment of several immune cells is triggered. Infiltration of tumor-associated macrophages (TAMs) is corre

Externí odkaz: https://doaj.org/article/0535ef0dd6234ee3920f7be35c2ca8d1

Pharmacokinetic analysis of 11C-PBR28 in the rat model of herpes encephalitis (HSE): comparison with (R)-11C-PK11195

Autor: Erik F. J. de Vries, Paula Kopschina Feltes, David Vállez García, Cristina Maria Moriguchi Jeckel, Andrea Parente, Rudi Dierckx, Janine Doorduin, Jurgen W. A. Sijbesma

Publikováno v: Journal of Nuclear Medicine, 57(5), 785-791. Society of Nuclear Medicine Inc.
Parente, A, Feltes, P K, Vállez García, D, Sijbesma, J W A, Jeckel, C M M, Dierckx, R A J O, De Vries, E F J & Doorduin, J 2016, ' Pharmacokinetic analysis of 11 C-PBR28 in the rat model of herpes encephalitis : Comparison with (R)-11 C-PK11195 ', Journal of Nuclear Medicine, vol. 57, no. 5, pp. 785-791 . https://doi.org/10.2967/jnumed.115.165019
Journal of Nuclear Medicine, 57(5), 785-791. SOC NUCLEAR MEDICINE INC

11C-PBR28 is a second-generation translocator protein (TSPO) tracer with characteristics supposedly superior to the most commonly used tracer for neuroinflammation, (R)-11C-PK11195. Despite its use in clinical research, no studies on the imaging prop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8dd569fee2a21f8984d799dbe95a1cc
https://doi.org/10.2967/jnumed.115.165019

O uso da Tomografia por Emissão de Pósitrons (pet) no diagnóstico das doenças neurodegenerativas do idoso

Autor: Cristina Maria Moriguchi Jeckel

Publikováno v: PAJAR-Pan American Journal of Aging Research; Vol. 5 No. 1 (2017); 1-3
PAJAR-Pan-American Journal of Aging Research; Vol. 5 Núm. 1 (2017); 1-3
PAJAR-Pan-American Journal of Aging Research; v. 5 n. 1 (2017); 1-3
PAJAR-Pan American Journal of Aging Research
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUCRS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff196d58e5343b900c4e805854c8ccca
https://doi.org/10.15448/2357-9641.2017.1.28022

Antidepressant Effects of Ketamine Are Not Related to ¹⁸F-FDG Metabolism or Tyrosine Hydroxylase Immunoreactivity in the Ventral Tegmental Area of Wistar Rats

Autor: Pedro Porto Alegre, Baptista, Lisiani, Saur, Pamela Bambrilla, Bagatini, Samuel, Greggio, Gianina Teribele, Venturin, Sabrina Pereira, Vaz, Kelly Dos Reis, Ferreira, Juliana Silva, Junqueira, Diogo Rizzato, Lara, Jaderson Costa, DaCosta, Cristina Maria Moriguchi, Jeckel, Régis Gemerasca, Mestriner, Léder Leal, Xavier

Publikováno v: Neurochemical research. 40(6)

Major depressive disorder (MDD) is an important health problem that is often associated to stress. One of the main brain regions related to MDD is the ventral tegmental area (VTA), a dopaminergic center, part of the reward and motivation circuitry. R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cdd29b794897e89629058432849f6586
https://pubmed.ncbi.nlm.nih.gov/25894683

Glucocorticoids and DHEA: Do They Have a Role in Immunosenescence?

Autor: Moisés Evandro Bauer, Clarice Luz, Flávia Ribeiro, Cristina Maria Moriguchi Jeckel, Cristina Bonorino

Publikováno v: Handbook on Immunosenescence ISBN: 9781402090622

This chapter summarizes recent work suggesting that human immunosenescence may be closely related to both psychological distress and stress hormones. The age-related immunological changes are also similarly found during chronic stress or glucocortico

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66983ec0e2aa46f3945f73d0562c68c7
https://doi.org/10.1007/978-1-4020-9063-9_43