Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cristina Maria Cruciat"'
Autor:
Edoardo Fatti, Alexander Hirth, Andrea Švorinić, Matthias Günther, Gunter Stier, Cristina-Maria Cruciat, Sergio P. Acebrón, Dimitris Papageorgiou, Irmgard Sinning, Jeroen Krijgsveld, Thomas Höfer, Christof Niehrs
Publikováno v:
Science Signaling. 16
DDX RNA helicases promote RNA processing but DDX3X is also known to activate casein kinase 1 ε (CK1ε). Here we show that not only is protein kinase stimulation a latent property of other DDX proteins towards CK1ε, but that this extends to casein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f5bbc6d6f8d954ba3c36bffdf216c9
https://doi.org/10.1126/scisignal.abp8923
https://doi.org/10.1126/scisignal.abp8923
Autor:
Cristina Maria Cruciat, Hendrik C. Korswagen, Bisei Ohkawara, Christine Dolde, Carmen Reinhard, Reinoud E. A. de Groot, Christof Niehrs
Publikováno v:
Science Magazine, 339(6126), 1436-1441. American Association for the Advancement of Science (AAAS)
Casein kinase 1 (CK1) members play key roles in numerous biological processes. They are considered "rogue" kinases, because their enzymatic activity appears unregulated. Contrary to this notion, we have identified the DEAD-box RNA helicase DDX3 as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77febce704d4d1fcc620b146e463d8de
https://doi.org/10.1126/science.1231499
https://doi.org/10.1126/science.1231499
Autor:
Rosemary A. Stuart, Juliana Heidler, Heike Angerer, Valentina Strecker, Cristina-Maria Cruciat, Kathy Pfeiffer, Zibirnisa Kadeer, Heiko Giese, Ilka Wittig
Publikováno v:
Biochimica et biophysica acta. 1863(7 Pt)
Here we identified a hydrophobic 6.4 kDa protein, Cox26, as a novel component of yeast mitochondrial supercomplex comprising respiratory complexes III and IV. Multi-dimensional native and denaturing electrophoretic techniques were used to identify pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa5cb19b9a3d5a331fea367b9aa2fa5
https://pubmed.ncbi.nlm.nih.gov/27091403
https://pubmed.ncbi.nlm.nih.gov/27091403
Autor:
Cristina Maria Cruciat, Sergio P. Acebrón, Dierk Ingelfinger, Christof Niehrs, Bisei Ohkawara, Carmen Reinhard, Michael Boutros, Emil Karaulanov
Publikováno v:
Science. 327:459-463
Of Wnt, Prorenin Receptor, and V-ATPase The Wnt protein binds to receptors at the cell surface and regulates signaling pathways that control a wide range of critical biological processes from stem cell differentiation to generation of cancer. In a sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293bcf2d458130a2dae1eabc08838158
https://doi.org/10.1126/science.1179802
https://doi.org/10.1126/science.1179802
Autor:
Roberto Mayor, Sei Kuriyama, Ya Lin Huang, Christine Hassler, Cristina Maria Cruciat, Christof Niehrs
Publikováno v:
Development. 134:4255-4263
Kremen 1 and 2 (Krm1/2) are transmembrane receptors for Wnt antagonists of the Dickkopf (Dkk) family and function by inhibiting the Wnt co-receptors LRP5/6. Here we show that Krm2 functions independently from Dkks during neural crest (NC) induction i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5d2cf2c028df20ee3fd1eb347c6da0
https://doi.org/10.1242/dev.005942
https://doi.org/10.1242/dev.005942
Publikováno v:
Journal of Biological Chemistry. 281:12986-12993
Kremen1 and 2 (Krm1/2) are coreceptors for Dickkopf1 (Dkk1), an antagonist of Wnt/beta-catenin signaling, and play a role in head induction during early Xenopus development. In a proteomic approach we identified Erlectin, a novel protein that interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b1a40ee5f1d0d30968bec1b6b65ac7
https://doi.org/10.1074/jbc.m511872200
https://doi.org/10.1074/jbc.m511872200
Autor:
Cristina-Maria Cruciat
Publikováno v:
Current opinion in cell biology. 31
Casein kinase 1 (CK1) members play a critical and evolutionary conserved role in Wnt/β-catenin signaling. They phosphorylate several pathway components and exert a dual function, acting as both Wnt activators and Wnt inhibitors. Recent discoveries s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c0134663100f36631b34b93a77fd4c
https://pubmed.ncbi.nlm.nih.gov/25200911
https://pubmed.ncbi.nlm.nih.gov/25200911
Autor:
Michael Boutros, Cristina Maria Cruciat, Andrei Glinka, Christof Niehrs, Christine Dolde, Nadine Kirsch, Ya Lin Huang, Dierk Ingelfinger, Olga Kazanskaya
R-spondins are secreted Wnt signalling agonists, which regulate embryonic patterning and stem cell proliferation, but whose mechanism of action is poorly understood. Here we show that R-spondins bind to the orphan G-protein-coupled receptors LGR4 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f973da4757182fcc9aec9944887df8e9
https://europepmc.org/articles/PMC3185347/
https://europepmc.org/articles/PMC3185347/
Autor:
Christof Niehrs, Michael Boutros, Shunji Jia, Ying Wang, Cristina-Maria Cruciat, Qinghua Tao, Juan Liang, Yu Fu, Dierk Ingelfinger, Zhen Tong, Anming Meng, Wei Wu
Publikováno v:
Molecular and cellular biology. 31(13)
Wnt/β-catenin signaling is fundamental in embryogenesis and tissue homeostasis in metazoans. Upon Wnt stimulation, cognate coreceptors LRP5 and LRP6 ([LRP5/6] low-density lipoprotein receptor-related proteins 5 and 6) are activated via phosphorylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afcf90e7e21a1270c95501badb46288
https://pubmed.ncbi.nlm.nih.gov/21536646
https://pubmed.ncbi.nlm.nih.gov/21536646
Autor:
Angela Bauch, Tatjana Rudi, Bettina Huhse, Heinz Ruffner, Bernhard Kuster, Giulio Superti-Furga, Markus Bösche, Volker Gnau, Richard R. Copley, Bertrand Séraphin, Christina Leutwein, David Dickson, Jörg Schultz, Angela Edelmann, Malgorzata Schelder, Karin Klein, Roland Krause, Vladimir Rybin, Tewis Bouwmeester, Erich Querfurth, Gitte Neubauer, Martina Marzioch, Sonja Bastuck, Miro Brajenovic, Manfred Raida, Marie-Anne Heurtier, Manuela Hudak, Christian Höfert, Jens Rick, Anne-Claude Gavin, Anne-Marie Michon, Marita Remor, Gerard Drewes, Andreas Bauer, Alejandro Merino, Paola Grandi, Peer Bork, Cristina-Maria Cruciat
Publikováno v:
Nature, Vol. 415, No 6868 (2002) pp. 141-147
Most cellular processes are carried out by multiprotein complexes. The identification and analysis of their components provides insight into how the ensemble of expressed proteins (proteome) is organized into functional units. We used tandem-affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02a527148538b6da1761bcfc2a71f47
https://archive-ouverte.unige.ch/unige:157154
https://archive-ouverte.unige.ch/unige:157154