Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cristina Marculescu"'
Autor:
Cristina, Marculescu, Abirami, Lakshminarayanan, Joseph, Gault, James C, Knight, Lisa K, Folkes, Thomas, Spink, Carol V, Robinson, Katherine, Vallis, Benjamin G, Davis, Bart, Cornelissen
Publikováno v:
Chemical Communications (Cambridge, England)
Precise analyses reveal that, while useful in reducing heterogeneity, the use of TGases in site-selective Ab modification may still create unwanted ‘off-site’ conjugates.
Site-selective labelling of antibodies (Abs) can circumvent problems f
Site-selective labelling of antibodies (Abs) can circumvent problems f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d53b63d87b477dbfe70d92d01efc4044
https://pubmed.ncbi.nlm.nih.gov/31479092
https://pubmed.ncbi.nlm.nih.gov/31479092
Autor:
Stephen J. Paisey, Bart Cornelissen, Christopher Marshall, James C. Knight, Cristina Marculescu, Anwen Sian Williams, Adam M. Dabkowski
Publikováno v:
Dalton Transactions. 45:6343-6347
The most widely cited procedures for radiolabeling antibodies with zirconium-89 for immuno-PET require multi-milligram amounts of antibody which can be cost-prohibitive, particularly during the research and development process. We therefore sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e9024cba37e6f90fc98b9ed375bb08
https://doi.org/10.1039/c5dt04774a
https://doi.org/10.1039/c5dt04774a
Autor:
Cristina, Marculescu, Hanno, Kossen, Rachel E, Morgan, Patrick, Mayer, Sally A, Fletcher, Berend, Tolner, Kerry A, Chester, Lyn H, Jones, James R, Baker
Publikováno v:
Chemical communications (Cambridge, England). 50(54)
Tuning the properties of maleimide reagents holds significant promise in expanding the toolbox of available methods for bioconjugation. Herein we describe aryloxymaleimides which represent 'next generation maleimides' of attenuated reactivity, and de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd65eba53d7642f091defa4037e35088
https://pubmed.ncbi.nlm.nih.gov/24853662
https://pubmed.ncbi.nlm.nih.gov/24853662
Autor:
Lourdes Castañeda, James R. Baker, Vijay Chudasama, Elizabeth A. Hull, Richard J. Fitzmaurice, Antoine Maruani, João P. Nunes, Cristina Marculescu, Mark E. B. Smith, Trang M. Tran, Zoë V. F. Wright, Stephen Caddick, Lyn H. Jones
Publikováno v:
Tetrahedron Letters
Graphical abstract
Bromomaleimides are useful building blocks in synthesis and powerful reagents for the selective chemical modification of proteins. A mild new synthesis of these reagents is described, along with the convenient transferability
Bromomaleimides are useful building blocks in synthesis and powerful reagents for the selective chemical modification of proteins. A mild new synthesis of these reagents is described, along with the convenient transferability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f2f4c810d38c5edaed3bd0ca177f80
https://pubmed.ncbi.nlm.nih.gov/24058217
https://pubmed.ncbi.nlm.nih.gov/24058217