Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cristina M. Sandoval"'
Autor:
Victor Hong, Andres McKenzie, Jianhua Chao, Erin K Harning, Ping Li, Francis Burrows, Jiandong Shi, Rachel Lough, Theodore J. Yun, Marcus F. Boehm, Gerardo Ibanez, Ryan Lamer, Kenneth W Weichert, Christina Boykin, Anthone W. Dunah, Istvan J. Enyedy, Christine Ambrose, Noelito Timple, Ryan Van de Water, Marilyn R. Kehry, Marco A. Biamonte, Joseph Arndt, Jeffrey Thompson, Srinivas Rao Kasibhatla, Cristina M Sandoval, Karen Lundgren, Kevin Hong, Pamela A. Snodgrass-Belt, Sarah A. Bixler
Publikováno v:
Journal of Medicinal Chemistry. 55:7786-7795
Alkyne 40, 5-(2-amino-4-chloro-7-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-methylpent-4-yn-2-ol (EC144), is a second generation inhibitor of heat shock protein 90 (Hsp90) and is substantially more potent in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fc27a2a6949bbbf83404c803f06d5a
https://doi.org/10.1021/jm300810x
https://doi.org/10.1021/jm300810x
Autor:
Katarina Bartoš Jansen, Susan Lynn Baker, Marcelo C. Sousa, Sandra I. Metzner, Cristina M. Sandoval
Publikováno v:
Journal of Molecular Biology. 409:348-357
Folding and insertion of integral β-barrel proteins in the outer membrane (OM) is an essential process for Gram-negative bacteria that requires the β-barrel assembly machinery (BAM). Efficient OM protein (OMP) folding and insertion appears to requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2c474a2b4dbe731452ad8e78b9c759
https://doi.org/10.1016/j.jmb.2011.03.035
https://doi.org/10.1016/j.jmb.2011.03.035
Outer membrane proteins (OMPs) of gram-negative bacteria are synthesized in the cytosol and must cross the periplasm before insertion into the outer membrane. The 17-kDa protein (Skp) is a periplasmic chaperone that assists the folding and insertion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8683b22e8a0cab38a091012f05d2f9
https://europepmc.org/articles/PMC2644113/
https://europepmc.org/articles/PMC2644113/
Structural evaluation of a novel pro-apoptotic peptide coupled to CNGRC tumor homing sequence by NMR
Autor:
Julio De Unamuno, Satoshi Fujimura, Leigh A. Plesniak, Lisa M. Ellerby, Taylor Williams, Patricia A. Jennings, Bernhard H. Geierstanger, H. Michael Ellerby, Jennifer A. Whiles‐Lillig, Calvin Balatbat, Cristina M. Sandoval
Publikováno v:
Chemical biologydrug design. 67(6)
Hunter-killer peptides (HKPs) are synthetic peptides that target specific cell types for apoptosis. These studies report functional and structural characteristics of HKP9, an hunter-killer peptide that specifically targets tumor vasculature with a ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4905082f9b7079618d169f7cd993ebd0
https://pubmed.ncbi.nlm.nih.gov/16882316
https://pubmed.ncbi.nlm.nih.gov/16882316
Autor:
Leigh A. Plesniak, Kristine Reyes, Taylor Williams, Cristina M. Sandoval, Valerie S. Hohman, Bridget Salzameda
Publikováno v:
FEBS Letters. (28):5464-5468
Peptides that target tissue for an apoptotic death have potential as therapeutics in a variety of disease conditions. The class of peptides described herein enters the cell through a specific receptor-mediated interaction. Once inside the cell, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5cf5ddf3e1f8bf7125d3939547a8d5