Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Cristina M. Ramírez"'
Autor:
Juan Francisco Aranda, Ana Pérez-García, Marta Torrecilla-Parra, Mario Fernández-de Frutos, Yolanda Martín-Martín, Pedro A. Mateos-Gómez, Virginia Pardo-Marqués, Rebeca Busto, Cristina M. Ramírez
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Hypoxia is a crucial factor contributing to maintenance of atherosclerotic lesions. The ability of ABCA1 to stimulate the efflux of cholesterol from cells in the periphery, particularly foam cells in atherosclerotic plaques, is an important anti-athe
Externí odkaz:
https://doaj.org/article/7e3688707c2447a2b7b085299891ff89
Autor:
Noemi Rotllan, Xinbo Zhang, Alberto Canfrán-Duque, Leigh Goedeke, Raquel Griñán, Cristina M. Ramírez, Yajaira Suárez, Carlos Fernández-Hernando
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113419- (2022)
Objective: miR-148a-3p (miR-148a) is a hepatic and immune-enriched microRNA (miRNA) that regulates macrophage-related lipoprotein metabolism, cholesterol homeostasis, and inflammation. The contribution of miR-148a-3p to the progression of atheroscler
Externí odkaz:
https://doaj.org/article/2ef32137959041b0bd54a61fb1582ef7
Autor:
José María Medina-Gil, Ana Pérez-García, Pedro Saavedra-Santana, Asunción Díaz-Carrasco, Efrén Martínez-Quintana, Fayna Rodríguez-González, Cristina M. Ramírez, Marta Riaño, Paloma Garay-Sánchez, Antonio Tugores
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Monocytes participate in the development of atherosclerosis through the action of cytokines and other inflammatory mediators. Among them, CCR2 and its ligands, CCL2 and CCL7 play an important role, so the main objective of this work was to determine
Externí odkaz:
https://doaj.org/article/c7b07c933f2b40649069f189340042ed
Autor:
Natividad Aguayo, Cristina M. Ramírez
Publikováno v:
Research in Learning Technology, Vol 28, Iss 0, Pp 1-26 (2020)
Given the social impact and the transformation of the teaching–learning process enhanced by new technologies, online language learning has been established as a field of study that has been approached primarily from the perspective of pedagogical t
Externí odkaz:
https://doaj.org/article/bf931bc994c642d18ae58e21debaaeab
Autor:
Yolanda Martín-Martín, Ana Pérez-García, Marta Torrecilla-Parra, Mario Fernández-de Frutos, Virginia Pardo-Marqués, María José Casarejos, Rebeca Busto, Cristina M. Ramírez
Publikováno v:
Cells, Vol 11, Iss 16, p 2538 (2022)
The evident implication of the insulin-degrading enzyme (IDE) in Alzheimer’s disease (AD) and type 2 diabetes mellitus (T2DM), among its capacity to degrade insulin and amyloid-β peptide (Aβ), suggests that IDE could be an essential link in the r
Externí odkaz:
https://doaj.org/article/8181e1a111a94735bbf59ba2e3c66528
Autor:
Cristina M. Ramírez, Marta Torrecilla-Parra, Virginia Pardo-Marqués, Mario Fernández de-Frutos, Ana Pérez-García, Carlos Tabraue, Juan Vladimir de la Rosa, Patricia Martín-Rodriguez, Mercedes Díaz-Sarmiento, Uxue Nuñez, Marta C. Orizaola, Paqui G. Través, Marta Camps, Lisardo Boscá, Antonio Castrillo
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Macrophages are immune cells that play crucial roles in host defense against pathogens by triggering their exceptional phagocytic and inflammatory functions. Macrophages that reside in healthy tissues also accomplish important tasks to preserve organ
Externí odkaz:
https://doaj.org/article/ea4acb3b988442639352fea5ae961d3d
Autor:
Ana Pérez-García, Marta Torrecilla-Parra, Mario Fernández-de Frutos, Yolanda Martín-Martín, Virginia Pardo-Marqués, Cristina M. Ramírez
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 208 (2022)
Insulin resistance defines an impairment in the biologic response to insulin action in target tissues, primarily the liver, muscle, adipose tissue, and brain. Insulin resistance affects physiology in many ways, causing hyperglycemia, hypertension, dy
Externí odkaz:
https://doaj.org/article/6dc4796341864a54ac9906476d1ec349
Autor:
Pedro Reimunde, Alba Pensado-López, Martín Carreira Crende, Vanesa Lombao Iglesias, Laura Sánchez, Marta Torrecilla-Parra, Cristina M. Ramírez, Clément Anfray, Fernando Torres Andón
Publikováno v:
Cancers, Vol 13, Iss 5, p 1087 (2021)
Glioblastoma (GBM) is the most common of all brain malignant tumors; it displays a median survival of 14.6 months with current complete standard treatment. High heterogeneity, aggressive and invasive behavior, the impossibility of completing tumor re
Externí odkaz:
https://doaj.org/article/056a3b868e6b417cb2f2a90f2ef61059
Autor:
Jan R. Kraehling, John H. Chidlow, Chitra Rajagopal, Michael G. Sugiyama, Joseph W. Fowler, Monica Y. Lee, Xinbo Zhang, Cristina M. Ramírez, Eon Joo Park, Bo Tao, Keyang Chen, Leena Kuruvilla, Bruno Larriveé, Ewa Folta-Stogniew, Roxana Ola, Noemi Rotllan, Wenping Zhou, Michael W. Nagle, Joachim Herz, Kevin Jon Williams, Anne Eichmann, Warren L. Lee, Carlos Fernández-Hernando, William C. Sessa
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Atherosclerosis is caused by low-density lipoprotein (LDL) buildup in the vessel wall, a process thought to be mediated by LDL receptor alone. Here, the authors show that the endothelium can uptake LDL via ALK1, a TGFβ signalling receptor, suggestin
Externí odkaz:
https://doaj.org/article/745c383654124c2b97ea3d105429cf8d
Autor:
Asier Benito-Vicente, Kepa B. Uribe, Noemi Rotllan, Cristina M. Ramírez, Shifa Jebari-Benslaiman, Leigh Goedeke, Alberto Canfrán-Duque, Unai Galicia-García, Diego Saenz De Urturi, Patricia Aspichueta, Yajaira Suárez, Carlos Fernández-Hernando, Cesar Martín
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8675 (2020)
Insulin resistance (IR) is one of the key contributing factors in the development of type 2 diabetes mellitus (T2DM). However, the molecular mechanisms leading to IR are still unclear. The implication of microRNAs (miRNAs) in the pathophysiology of m
Externí odkaz:
https://doaj.org/article/0e48fd21c1a34a35bbca77b3cf0f1e9f